Sammy
@NeuroSGS
PhD student in Neuroscience. Research interests include sex differences in the brain, sexual orientation, and gender dysphoria.
My pinned thread of threads, primarily containing citations and explanations about neurological/ psychological sex differences, sexuality, gender dysphoria, and other academic research interests of mine:
What we know in general is that male brains are larger than female brains, on average (typically a 9-13% difference). This includes overall grey matter volume (cortical and sub-cortical), white matter volume, and cerebrospinal fluid volume (also enlarged ventricles). When natal…
Nonsense from Miller here. 🙄 As cells and tissues age, they can shed chromosomes. The most obvious time point is during division, and the older you are, the more cells you’ve divided, the higher the chances some of them have lost a chromosome or two. This happens to both…
Are there sex differences in the human brain? “While the Paradox Institute, including myself, rejects the notion of a strict male-female brain dichotomy, we firmly assert that, despite the observed variation, biological sex remains a significant variable impacting the brain”
Who wrote this, and what article is it from!? I want to have words with the author! 😂
Ask him what he views as the biggest challenges in accurately reporting neurological sex differences? Additionally, what he believe is the most appropriate way to control for brain size (if it should be controlled for at all) and why?
I’m hosting a guest on Huberman lab podcast who is the world expert on sex differences in the brain- how differences not only in hormones, but in gene expression make males and females think and feel and act very differently to the same thing. What would you like me to ask them?
𝐓𝐡𝐫𝐞𝐞-𝐏𝐚𝐫𝐭 𝐐𝐮𝐞𝐬𝐭𝐢𝐨𝐧 𝐨𝐧 𝐍𝐞𝐮𝐫𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐒𝐞𝐱 𝐃𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐜𝐞𝐬: 1) What are the key criteria that define a well-designed scientific study in the context of investigating sex differences in the human brain? 2) Are there existing studies that…
You cannot scan a transgender individuals brain, identify a difference, and claim you’ve discovered “gender identity”. Some activists will claim it’s one region, while others suggest a different one. Once again, no consistency in their arguments
This seems oddly specific 🤔 What are these 64 sexually dimorphic nuclei? Where did you get this number from, and how reproducible is each of these in the literature. As for the BSTc, we literally have data showing sex-specific changes way into adulthood.
2. There are 64 sex dimorphic (ie different in each sex) nuclei; groups of cells, in human brains What SDNs do, is not yet known Limited research into 1 SDN: the BST, has shown cells do not change - post-birth - w/ hormone therapy But a BST in TW resembles that in non-T women
Sex hormones influence nearly every organ, system, and biological process in the human body, including the immune system, cardiovascular function, gut microbiome, mitochondrial activity, and skeletal muscle. There is no biological rationale to assume the brain would be exempt…
Ask yourself, why? Are there any variables in these studies that may produce the same outcome? 🤔 It’s not a settled fact…
It HAS been observed that trans women brain structure is closer to the ones of cis women than of cis men tho. Like that IS a fact
First, what is the hypothesis you’re testing? If you’re proposing that a specific brain structure or set of structures is responsible for “gender distress,” then start by clearly stating your a priori hypothesis. Which regions do you predict will differ, and on what basis? What…
Uh science does confirm the existence of transgenderism, like it is heavily scientifically supported-
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