Luca Naef
@NaefLuca
Co-Founder & CTO, @vant_ai Forbes 30u30 but won't go to jail | prev. ETH Zurich Stanford McKinsey AI x Bio/Chem. vi/vim
Extremely excited to give a glimpse of what we've been working on over the past 2 years: unifying structure-prediction and de-novo generation. Neo-1 is an all-atom, fully generative model
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)
Apply for the AITHYRA-CeMM International PhD Program! 15-20 fully funded PhD fellowships available in Vienna in AI/ML and Life Sciences Deadline for applications: 10 September 2025 apply.cemm.at
Aithyra Opening Symposium "AI for Life Science" with Nobel Laureate Frances Arnold as keynote speaker in addition to an outstanding line up of speakers on a variety of topics across biological scales and data modalities. Registration is now open at lnkd.in/dkJJCmqx
Thank you so much for your close partnership! Not possible with you and the incredible community behind these foundational technologies!
Neo just got much faster!💥 Working closely with @NVIDIAHealth , VantAI adopted #cuEquivariance, leading to massive speedups. Today's announcement is a big advancement for the field!
Second expansion and couldn't be more excited - it's been a privilege to be working with such a talented team at Blueprint!
Excited to announce our second expansion in three years with @BlueprintMeds. Together, we will prioritize novel target-effector pairs for molecular glue development, aiming at previously undruggable targets, using our proximity modulator discovery platform powered by our Neo-1…
last night's @airstreet nyc ai meetup hosted at @awscloud showcased sota coding agents, workflow agents, generative user interfaces and protein and molecular design tools. some seriously impressive demos from: - @ashedwardst of @Fern_Labs with long-running computer agents -…
🗽 @airstreet nyc ai meetup 4/15 lineup complete, welcoming: - @NaefLuca, cto/co-founder of @vant_ai (fresh off neo-1 model launch!) - @Albertorizzoli, ceo/co-founder of @V7Labs 150 members of the research, product, eng ai community in new york! rsvp: airstreet(dot)com/nycai
our first 2 speakers @airstreet nyc ai meetup on 4/15 - @tylerangert of @patinasystems, spontaneous software, formerly of @replit - @ashedwardst of @fern_labs, multi-agent systems to write software, formerly of @palantirtech +2 more coming soon! rsvp: airstreet(dot)com/nycai
Congratulations to the entire VantAI team on an incredible step forward for generative molecular design. And proud that @NVIDIAHealth was able to play a small part to ensure Neo-1 goes brrrrrrrrrrrr....
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)
The @vant_ai team is breaking my X feed 🤣. Congrats on Neo-1 _everywhere_ @NaefLuca @zwcarpenter @mmbronstein and many more!
Combining prediction, generation, and modalities (sequence, structure, nucleic acids, small molecules, proteins) is the future. Congrats to the authors! Looking forward to the technical report.
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)
Really cool to see Neo-1 released. Latent diffusion to combine structure prediction and molecular generation across modalities. #ai #drugdiscovery #genai
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)
this wouldn’t have been possible without the help amazing folks at @NVIDIAHealth, GPU-mmseqs2 MSA was a critical piece for both inference and data gen
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)
The heroes of this story of course is the absolutely cracked group of people that made this possible. And you can join them! [email protected]
This would’ve not been possible without the team behind it: @clemensisert, Michael Pun, @emaros96, Thomas Castiglione, Douglas Tischer, @AkdelMehmet, @dannykovtun, @MPegoraro42, Thomas Duignan, @a1zhang, @OleinikovasV, Graham Holt, @ShinaYusuf_, Patrick Kunzmann, Arjun Ramesh,…
Big news from @vant_ai: Neo-1 integrates SOTA structure prediction and all-atom molecular generation into a single unified model -- an industry first to the best of my knowledge: vant.ai/neo-1
The era of rewiring protein interactions to treat disease is emerging all around us. AI will play a critical role in this unfolding story and we are thrilled to announce Neo-1, the first foundation model designed specifically with this incredible new modality in mind. Congrats to…
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)
Was a pleasure to give @AndrewE_Dunn an early peak who did a great job summarizing what this will enable, go read more about it below!
“It tackles the big next step after AlphaFold 3,” Luca Naef, VantAI’s chief technology officer, told me. I talked with @zwcarpenter, @NaefLuca, and @mmbronstein on VantAI's most substantive update since its 2019 start My exclusive for @endpts on Neo-1: endpts.com/exclusive-vant…
Announcing Neo-1: the world’s most advanced atomistic foundation model, unifying structure prediction and all-atom de novo generation for the first time - to decode and design the structure of life 🧵(1/10)