Murthy Lab
@MurthyLab
We are a neuroscience laboratory interested in neural mechanisms of social communication.
Excited to announce the completion of the first adult brain connectome - FlyWire is the neuronal wiring diagram of a Drosophila melanogaster brain with >130K neurons and >32M synapses. Explore at codex.flywire.ai. Check out the preprints:
We are releasing a whole-brain connectome of the fruit fly, including ~130k annotated neurons and tens of millions of typed synapses! Explore the connectome: codex.flywire.ai Reconstruction paper: biorxiv.org/content/10.110… Annotation paper: biorxiv.org/content/10.110… 1/6
We've updated our preprint on finding one-to-one mappings of DNN neurons and real visual neurons of fruit fly. --> 2x silenced data with new LC31 neuron type --> more LC neural recordings --> FlyWire connectome --> knockout training simulations Enjoy! tinyurl.com/5n7t6tpv
Excited to share a new manuscript! Deep nets are great at predicting visual neurons. Yet, they are unable to tell us which artificial neuron directly corresponds to a biological neuron… until now! biorxiv.org/content/10.110… (yes, that is indeed a fictive female fly, good guess!)
Don’t miss out on the Neural Mechanisms of Acoustic Communication GRC - this May in Maine!
1) Time to submit abstracts! The 2024 Neural Mechanisms of Acoustic Communication GRC is drawing closer. There's an awesome line-up of speakers working with birds, flies, monkeys, fish, snakes and more. Additional speakers will be selected from abstracts. Please spread the word!
How are neurons activated by sensory stimuli? For the past century, the only method for addressing this question has been neurophysiology.
We are excited to announce that registration is open for the 2024 Neural Mechanisms of Acoustic Communication Gordon Research Conference. The preliminary program is now live: grc.org/neural-mechani… We invite everyone to apply! See you @ Sunday River, Maine, May 19-24, 2024.
This might make you think twice next time you reach for the fly swatter. The whole brain wiring diagram of the fly! All 140,000 neurons and their 50M synapses are available to explore in Codex, the Connectome Data Explorer: codex.flywire.ai #sfn23
Flies are highly visual animals. That’s obvious to anyone who has ever tried to swat one. So it should be no surprise that eyes are so prominent on the fly head.
Excited to announce that I'm starting my group @ucl with @wellcometrust funding in 2023. We'll investigate audiovisual integration with the latest electrophysiology and optogenetic tools. DM me if you'd like to join as a postdoc, student, or tech. Or say hello at 329.23. #SfN2022
The fly central brain synthesizes sensory stimuli into decisions and actions. For the first time, ALL 46,944 branched and far-reaching neurons of both hemispheres of the central brain have been reconstructed and are available via FlyWire. join.flywire.ai
Officially out today @CurrentBiology! Check out @MurthyLab collaborative effort to map and record from fly auditory neurons to build the first auditory wiring diagram in any system. cell.com/current-biolog…
yessss it's #BINW22 !! I'm Sama Ahmed, finishing my postdoc in the @MurthyLab at @PrincetonNeuro and starting my lab at @UWPsychology in 5 weeks ! We test how circuit interactions constrain behavior by studying how flies multitask ! @BlackInNeuro #BlackInNeuroRollCall
Take a look at the first auditory connectome! New paper utilizing FlyWire from @Christa_A_Baker et al in @CurrentBiology: cell.com/current-biolog… Shoutout to @Drexel_Pretzel who created the drosophila serenade illustration in our graphical abstract. @MurthyLab
Also excited to announce that @BenjoCowley is starting his own lab @CSHL in the Fall. If you want to work on neural network models of the brain, this is the lab to join!
Update of potential interest: I'll be starting a comp neuro group at Cold Spring Harbor Laboratory @CSHL in Sept 2022! Our group will build closed-loop machine learning techniques and interpretable, data-driven models to understand the step-by-step computations of the brain.
So proud of @Christa_A_Baker - get in touch to do a postdoc in the Baker lab @NCState - Christa is a fabulous mentor, scientist and role model and her lab will be a trailblazer in solving the neural mechanisms underlying acoustic communication in flies.
Excited to share that the Baker Lab will open in Biological Sciences @NCState Jan 2023! We will dissect the neural mechanisms underlying hearing in flies, and how those mechanisms are shaped by evolution. Will be recruiting at all levels so please reach out if interested.