maurizio molinari
@MolinariLab
Cell biologist, Mechanistic dissection of protein folding, quality control, degradation, UPR, and ER-phagy pathways. Non sono direttore di giornale. My opinions
ATZ polymers elicit intervention of the CNX:FAM134B-LC3II segregation complex and formation of VAPA-ORP1L-RAB7 membrane contact sites that facilitate Syntaxin18/VAMP8-driven fusion of ER and endolysosomal membrane: ER-to-Lysosome-Associated Degradation. biorxiv.org/content/10.110…
I would like to warmly thank the ALPHA-1 Foundation for the important support allocated to our research project “Understanding the Molecular Mechanisms of Lysosomal Clearance of ATZ Polymers". A1F recognizes 2025 Grant Award Recipients during ATS alpha1.org/a1f-recognizes…
![MolinariLab's tweet card. On Monday, May 19th, 2025, the Alpha-1 Foundation (A1F) hosted its annual A1F Grants Award Reception at the San Francisco [...]Read More... from A1F recognizes 2025 Grant Award Recipients during ATS](https://pbs.twimg.com/card_img/1948079170321268736/wCtnZBze?format=jpg&name=orig)
New Online! Key challenges and recommendations for defining organelle membrane contact sites bit.ly/4lnIBP1
🚨 New review out in Nature Reviews Molecular Cell Biology! Expert recommendations for studying organelle contact sites and introduce the concept of organelle contactome 🧬nature.com/articles/s4158… Huge thanks to editor Lisa Heinke for the support and guidance! 🙏@NatRevMCB
📼 ⏮️ 𝑯𝒆'𝒔 𝑩𝒂𝒄𝒌! Bentornato a casa Gjanni! 🤍🖤 #noibianconeri #fclugano #lugano
Early morning discussion about see turtles with Jeff Brodsky. FASEB Endoplasmic Reticulum meeting, Melbourne, Florida. @FASEBorg
Dan, a friend for many of us, passed at the end of last year. Before leaving, with his students and colleagues, he prepared this gift. Amazing. N-glycan-dependent protein maturation and quality control in the ER | Nature Reviews Molecular Cell Biology nature.com/articles/s4158…
Two structurally targeted allosteric regulators of GCase folding promote lysosomal transport of disease-causing variants, reduce ER stress and rescue lysosomal functions. Therapeutic potential for GD, PD, and Dementia with LB. mdpi.com/3299382 #mdpiijms via @IJMS_MDPI
Uncovering ERLAD: the ER-to-Lysosome Associated Degradation of large, aggregated, disease-causing, nasty misfolded proteins that fail to enter proteasomal-driven ERAD pathways. sciencedirect.com/science/articl…
We’re proud to share that the Alpha-1 Foundation has been named one of the 2025 Best Nonprofits to Work For by @NonProfitTimes ! This recognition reflects our ongoing commitment to fostering a mission-driven culture that values collaboration, innovation, and impact. Read more:…
We wish you and your loved ones a happy and meaningful Easter. 💐
Alpha-1 doesn’t just affect the lungs, it can impact the liver, too. On #WorldLiverDay, we’re shining a light on Alpha-1 liver disease and the importance of early diagnosis and support. To learn more about Alpha-1 and the liver, visit: alpha1.org/liver-disease/ #Alpha1Awareness
For those new to scientific research, please remember that the only thing that matters is the REPRODUCIBILITY of your study, not the impact factor or journal name. Thank you.
for those new to scientific research, plz remember that “nature” is most definitely not the same thing than “nature communications” 5x gap in impact factor - nature papers make careers, nat comms make blog posts
Look at the table if you wish to become a healthy old man/woman/…. It’s from today’s Nature Medicine by A.-J. Tessier et al. Optimal dietary patterns for healthy aging. Hopefully somebody will soon publish conflicting results proving that desserts are not that bad, after all.
Interested in advanced light #microscopy and #biophysics? Join Francisco Balzarotti’s group through the Vienna BioCenter #PhD Program (@TrainingVbc)! ⏳ Deadline: April 15. Apply now: training.vbc.ac.at/phd-program 📷Watch Francisco's 'Scientist Snapshot': youtube.com/watch?v=xAjosh…
This is shameful! @ETH_en or @EPFL is ok with supporting #predatory_journals ???
22 Swiss universities and research institutions have agreed to extend their partnership with MDPI for 2025. The agreement negotiated by CSAL is valid until the end of this year. Learn more: brnw.ch/21wRk0d #MDPI #OpenAccess #GoldOA
