MetaStem

Follow MetaStem, The Centre of Excellence in Stem Cell Metabolism on Bluesky 🦋 Seuraa meitä Blueskyssa bsky.app/profile/metast…

News from our CoE by @HTyynismaa group characterize the role of mitochondrial intermembrane space protein CHCHD10 in metabolism and spinal muscular atrophy Jokela type (SMAJ) actaneurocomms.biomedcentral.com/articles/10.11… Congratulations Sandra Harjuhaahto! @SuomenAkatemia @helsinkiuni @STEMMProgram

Tomorrow, welcome!

Excited to have @HKilpinen and special guest @ChristianGoritz opening the Stem Cell Seminars of 2025 with focus on neurodevelopment, regeneration and fibrotic scarring in the CNS. Jan 23rd 9 am, welcome! @MIBS_Helsinki @BIOTECH_UH @LifeSciHelsinki @HelsinkiUniMed

Proudly presenting Simon’s paper on asymmetric apportioning of old mitochondria biasing intestinal stem cells for the Paneth cell linage through aKG-dependent metabolism @NatMetabolism nature.com/articles/s4225… @helsinkiuni @HiLIFE_helsinki @SuomenAkatemia @MetaStem_Center

New from our CoE by @KatajistoLab show how tissue stem cells can metabolically regulate tissue renewal and differentiation by providing daughter cells with peroxisomes of different age and metabolic properties nature.com/articles/s4146… @SuomenAkatemia @helsinkiuni @HiLIFE_helsinki

A new study from our CoE finds that stem cells can control whether they self-renew or differentiate by localizing certain metabolic reactions differently helsinki.fi/en/faculty-bio… @SuomenAkatemia @helsinkiuni @KatajistoLab @BIOTECH_UH @MIBS_Helsinki @_HienBui @PekkaKatajisto

Happy to present Hien’s paper on age-selective apportioning of peroxisomes as a fate determinant in adult stem cells nature.com/articles/s4146… @MetaStem_Center @helsinkiuni @karolinskainst @BIOTECH_UH @MIBS_Helsinki @SuomenAkatemia out now in @NatureComms Congrats @_HienBui et al!

Next Stem Cell Seminar April 23rd, welcome! bsky.app/profile/metast… @HelsinkiUniMed @HiLIFE_helsinki @STEMMProgram @BIOTECH_UH @FIMM_UH

The @KatajistoLab modeled #epithelial regeneration using small intestinal scaffolds and identified #asporin is a mediator of fetal-like reprogramming. Read the @CellStemCell article: bit.ly/41LJbhn Listen to the conversation: bit.ly/3FBkNHR

Welcome to the next Metabolism seminar, March 18th at 9-11 am in Meilahti. Excellent speaker lineup with and @DrPietilainen and Robin Cristofari groups presenting about #obesity #adiposetissue #diet #aging in humans and penguins @STEMMProgram @BIOTECH_UH @HelsinkiUniMed

Online Now! Fetal-like reversion in the regenerating intestine is regulated by mesenchymal asporin dlvr.it/TJMj7h #stemcells

Proudly presenting Sharif’s paper on the role of Asporin in intestinal regeneration through TGF-B-dependent fetal-like reversion sciencedirect.com/science/articl… out now in @CellStemCell @helsinkiuni @SuomenAkatemia @BIOTECH_UH @MIBS_Helsinki @PekkaKatajisto Read our thread on Bluesky🦋

Welcome @ChristianGoritz on Jan 23rd. Excited to hear about your research on perivascular fibroblasts, scarring and regeneration of the central nervous system. The seminar is part of the Stem Cell Seminar series and open to all @LifeSciHelsinki @HelsinkiUniMed @HiLIFE_helsinki

New collaborative study of @HannesLohi lab together with @HTyynismaa lab @julius_ronkko from our CoE. Surprising findings in Lancashire Heeler dogs shed light on CMT disease mechanisms journals.plos.org/plosgenetics/a… Congratulations to all authors! @helsinkiuni @SuomenAkatemia

💥Postdoc position open for highly motivated enthusiast of hematopoietic stem cells at Karolinska Institutet @karolinskainst in Sweden 🇸🇪Link here: ki.varbi.com/what:job/jobID… Please RT We are excited for your application!😃