Matthew Watt

@MattWattUnimelb

Researcher in metabolism, NAFLD and type 2 diabetes at the University of Melbourne. Associate Dean Research, Faculty of Medicine Dentistry & Health Sciences

Joined November 2018

119Following

2KFollowers

Matthew Watt@MattWattUnimelb · Apr 21

Incredibly proud of this work. We detail the evolution of liver-secreted and plasma proteins with MASLD progression, providing a rich resource defining human hepatokines and a predictive model that stratifies MASH. @will_denardo @UniMelbMDHS cell.com/cell-reports-m…

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Matthew Watt@MattWattUnimelb · Mar 30

Pleased to share our recent work showing the protein HEXA improves #muscle insulin sensitivity in mice with type 2 #diabetes. Superbly led by Magda Montgomery @UniMelbMDHS rdcu.be/efJo0

MattWattUnimelb's tweet image. Pleased to share our recent work showing the protein HEXA improves #muscle insulin sensitivity in mice with type 2 #diabetes. Superbly led by Magda Montgomery @UniMelbMDHS

rdcu.be/efJo0

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Matthew Watt@MattWattUnimelb · Mar 25

AFL football alive and well with FIVE teams training at Lysterfield Junior Football Club. Keep those kids active!

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Matthew Watt@MattWattUnimelb · Mar 3

Pleased to share our newest paper describing a new mechanism for fatty acid transfer between lipid droplets and mitochondria, which is important for regulating fatty acid oxidation. A wonderful team effort and work that I’m extremely proud of. nature.com/articles/s4146…

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Matthew Watt@MattWattUnimelb · Mar 1

Pleased to share our new review with @DrGregSteinberg outlining the role of the gut-adipose tissue-liver axis in MASLD. Integrative Metabolism in MASLD and MASH: Pathophysiology and Emerging... sciencedirect.com/science/articl…

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Matthew Watt@MattWattUnimelb · Dec 25

Great post doc opportunity in Melbourne

AA/Prof Garron Dodd@garrondodd · Dec 24

🚨 Join Our Team! 🚨 We’re on the hunt for a brilliant postdoctoral researcher with a passion for neuroscience or metabolic disease. This is your chance to work at the intersection of academia & industry, driving innovation in obesity & T2D research. 🌟 jobs.unimelb.edu.au/caw/en/job/919…

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Matthew Watt@MattWattUnimelb · Dec 21

Interesting read. Metabolic dysfunction-associated steatotic liver disease: heterogeneous pathomechanisms and effectiveness of metabolism-based treatment - The Lancet Diabetes & Endocrinology thelancet.com/journals/landi…

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Matthew Watt@MattWattUnimelb · Dec 19

Thrilled that the metabolism theme in Dept of Anatomy & Physiology were awarded NHMRC and ARC grants in #obesity #MASLD, #fibrosis and #aging. Go ⁦@garrondodd⁩ ⁦@Ben_Leo_Parker⁩ ⁦@MagdaMontg64866⁩ ⁦⁦@MattWattUnimelb⁩ 🎉💯🙂 ⁦@UniMelbMDHS⁩

MattWattUnimelb's tweet image. Thrilled that the metabolism theme in Dept of Anatomy &amp; Physiology were awarded NHMRC and ARC grants in #obesity #MASLD, #fibrosis and #aging. Go ⁦@garrondodd⁩ ⁦@Ben_Leo_Parker⁩ ⁦@MagdaMontg64866⁩ ⁦⁦@MattWattUnimelb⁩ 🎉💯🙂 ⁦@UniMelbMDHS⁩

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Matthew Watt@MattWattUnimelb · Dec 15

It was a pleasure to be part of the graduation ceremony for our Bachelor of Biomedicine students. All the more special because my niece was one of our newest graduates! @UniMelbMDHS

MattWattUnimelb's tweet image. It was a pleasure to be part of the graduation ceremony for our Bachelor of Biomedicine students. All the more special because my niece was one of our newest graduates!
@UniMelbMDHS

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Matthew Watt@MattWattUnimelb · Dec 12

Thrilled to share our latest work using Lipidome profiling in advanced metabolic liver disease which identified phosphatidylserine synthase 1 as a regulator of hepatic lipoprotein metabolism: Cell Reports cell.com/cell-reports/f… #MASH #liver @UniMelbMDHS

MattWattUnimelb's tweet card. Anari et al. show that hepatic accumulation of phosphatidylserine (PS) is associated with hypertriglyceridemia in metabolic dysfunction-associated steatohepatitis (MASH). Increasing expression of PS...

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Matthew Watt@MattWattUnimelb · Nov 28

Looking forward to learning about new therapeutic opportunities at the mRNA Vic symposium today (and presenting our new project for a MASH therapy). #MASLD #liver

MattWattUnimelb's tweet image. Looking forward to learning about new therapeutic opportunities at the mRNA Vic symposium today (and presenting our new project for a MASH therapy). #MASLD #liver

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Matthew Watt@MattWattUnimelb · Nov 26

Just spent two days at the Department of Anatomy and Physiology retreat. Inspired by the collegiality, openness and our future together. @UniMelbMDHS #nogolf!

MattWattUnimelb's tweet image. Just spent two days at the Department of Anatomy and Physiology retreat. Inspired by the collegiality, openness and our future together. @UniMelbMDHS #nogolf!

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Matthew Watt@MattWattUnimelb · Nov 21

Department of Anatomy and Physiology Research Day- kicked off with new tech session and now the ECRs are giving a 1 min teaser of their posters. Innovation and enthusiasm!! @UniMelbMDHS

MattWattUnimelb's tweet image. Department of Anatomy and Physiology Research Day- kicked off with new tech session and now the ECRs are giving a 1 min teaser of their posters. Innovation and enthusiasm!! @UniMelbMDHS

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Matthew Watt@MattWattUnimelb · Nov 20

New work showing lipolysis is essential for brown adipose thermogenesis (requires deletion of both ATGL and HSL).

DDominique Langin@DominiqueLangin · Nov 19

The research led by Prof. @Dominique Langin and Dr. @EMouiselsheds light on the importance of fat degradation in brown fat to generate heat. Exciting findings published in @Cell_Metabolism. @I2mcT @CHUdeToulouse @UT3PaulSabatier @Inserm 1/5 dlvr.it/TGGbFJ

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Matthew Watt@MattWattUnimelb · Nov 13

Our pleasure to host @jimmytrevaskis from Eli Lilly at the Department of Anatomy and Physiology at @UniMelbMDHS. Here sharing his experience in pharma with our early career fellows #obesity #therapy

MattWattUnimelb's tweet image. Our pleasure to host @jimmytrevaskis from Eli Lilly at the Department of Anatomy and Physiology at @UniMelbMDHS. Here sharing his experience in pharma with our early career fellows #obesity #therapy

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Matthew Watt@MattWattUnimelb · Nov 4

Some important reminders for those presenting their metabolomics data. | The EMBO Journal embopress.org/doi/full/10.10…

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Matthew Watt Retweeted

Mazen Noureddin, MD, MHSc@NoureddinMD · Nov 1

Breaking news. Sema hits both points for MASH resolution and Fibrosis improvement in the Ph 3 study! 62.9% vs 34.1% and 37% vs 22.5% respectively . Waiting to see F3, F2, titration and tolerance and drop out at #TLM24 #livertwitter @schattenbergJ @AlkhouriNaim @DrLoomba @EASLedu…

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Matthew Watt@MattWattUnimelb · Oct 30

Kit Ng presenting his final PhD oration on exercise phosphoproteomics and skeletal muscle at Dept of Anatomy and Physiology. Awesome to see the journey. @BenParkerLab @UniMelbMDHS

MattWattUnimelb's tweet image. Kit Ng presenting his final PhD oration on exercise phosphoproteomics and skeletal muscle at Dept of Anatomy and Physiology. Awesome to see the journey. @BenParkerLab @UniMelbMDHS

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Matthew Watt@MattWattUnimelb · Oct 29

New method to automate the interpretation of isotope tracing data for assessing metabolic flux- look useful but any consideration of assessing lipid flux?

JJason Locasale, PhD@LocasaleLab · Oct 29

Our study now @NatMetabolism. Analysis and expansion of machine learning approaches to automate the interpretation of isotope tracing data for assessing metabolic flux. Congrats Shiyu 🎉. rdcu.be/dX4Rp

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Matthew Watt@MattWattUnimelb · Oct 27

The search for the ‘best’ murine model of human fatty liver disease #MASLD. Most are useful but they all have limitations.

NNature Reviews Endocrinology@NatureRevEndo · Oct 24

New content online: Modelling human liver disease: from steatotic liver disease to MASH-HCC go.nature.com/4hkLCyo

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