Marius Lange
@MariusLange8
Postdoc between the @TreutleinLab @ETH_en and @dana_peer labs, developing ML tools for #singlecell genomics.
CellRank 2 is a comprehensive framework for cell fate analysis using large-scale multiview single-cell data. @PhilippWeiler7 @MariusLange8 @dana_peer @fabian_theis nature.com/articles/s4159…
I am really happy and excited to see CellRank 2 out in Nature Methods (nature.com/articles/s4159…)! @naturemethods @HelmholtzMunich @CompHealthMuc @TU_Muenchen @MariusLange8 @fabian_theis @dana_peer (1/16)
A great read for everyone interested in brain organoids! Congrats!
An integrated neural organoid atlas helps us all stand on the shoulders of great scientists! We explore coverage and fidelity, provide tools to assess new protocols, and use the diverse cohort to assess disease models. nature.com/articles/s4158…
Need to design your next Xenium/CosMx/Merfish experiment? Spapros, now out @naturemethods, allows for probe set selection for target spatial tx. Led by @KuemmerleLouis, it optimizes both cell type ID & within-cell type variation. nature.com/articles/s4159… github.com/theislab/spapr…
Amazing tool by @KuemmerleLouis, highly recommended.
Spapros developed by @fabian_theis and colleagues is a probe set selection and design pipeline for targeted spatial transcriptomics. nature.com/articles/s4159…
moslin combines lineage with state information to uncover cellular trajectories.
New Computational Tool Improves Understanding of Development and Healing 👉t1p.de/oogn0 💡The new computational tool "Moslin" empowers scientists to gain deeper insights into how cells make pivotal decisions during essential biological processes like development,…
I'll be in New York City until mid November, working in the amazing @dana_peer lab. Let me know if you're around and want to meet up / chat 🙂
Congrats @MariusLange8 @PhilippWeiler7 and team @fabian_theis @dana_peer !!! It’s a fantastic tool!
🥳Proud to be part of the team that developed CellRank 2, which just won the first Helmholtz software award: hifis.net/news/2024/07/1… @PhilippWeiler7 Michal Klein @fabian_theis @dana_peer ⌨️Learn more about the software and how you can use it here: cellrank.org
Proud to be part of the team behind this powerful, efficient and versatile tool, simply said a best way to do any type of pseudo-time analysis. Standing ovation to the exceptionally talented first authors @PhilippWeiler7 and @MariusLange8.
Advancing Single-Cell Analysis! 🚀 Prof. @fabian_theis & team at #HelmholtzMunich & @TU_Muenchen introduce #CellRank2! 👉t1p.de/z0t0c📝 💡This cutting-edge tool predicts #CellFates with unprecedented accuracy, revealing hidden pathways & potential therapeutic…
Excited that CellRank has just won the first @helmholtz_en software award, see hifis.net/news/2024/07/1… - congrats @PhilippWeiler7, @MariusLange8 & @dana_peer! - read about CellRank2 here nature.com/articles/s4159…
🥳Proud to be part of the team that developed CellRank 2, which just won the first Helmholtz software award: hifis.net/news/2024/07/1… @PhilippWeiler7 Michal Klein @fabian_theis @dana_peer ⌨️Learn more about the software and how you can use it here: cellrank.org
Advancing Single-Cell Analysis! 🚀 Prof. @fabian_theis & team at #HelmholtzMunich & @TU_Muenchen introduce #CellRank2! 👉t1p.de/z0t0c📝 💡This cutting-edge tool predicts #CellFates with unprecedented accuracy, revealing hidden pathways & potential therapeutic…
Nice application of CellRank 2 to uncover differentiation trajectories in a shared mRNA/protein latent space.
The gradual transitions of cell states led us to a trajectory analysis using CellRank. We found that the joint latent space is the superior input compared to CITE-seq or scp-MS data alone, indicating that the two modalities provide complementary information.
The gradual transitions of cell states led us to a trajectory analysis using CellRank. We found that the joint latent space is the superior input compared to CITE-seq or scp-MS data alone, indicating that the two modalities provide complementary information.
Very exciting to see our single-cell epigenomic atlas of human neural organoids published in @NatureNeuro !!! Fantastic work, Fides Zenk @EpiGN_lab, Jonas Fleck @josch_f and the whole team !!! @ETH_BSSE @IHB_Research
🚀Super happy that our latest research has finally been published in @NatureNeuro! We delve into the world of human neural development. Our findings shed light on the dynamic epigenetic changes that guide cell fate from pluripotency to fully differentiated neural cells.🧠🔬🧵
Congratulations Philipp! Great to see you gave a nice talk on this work at the conference!