Marcel Trefny

So excited to see our research published in @NatureComms today 🤩 rdcu.be/c4HIx Tweetorial below🧵Thanks to all the great people involved, including on Twitter: @AlfredZippelius @NKirchhammer @priska_adm @natoli_marina @LImmunotherapy @HessLab @maryam_akrami 1/10

Happy to present our 'Expert Opinion' on "CAR T cells for solid tumors – developments to watch in 2023" tandfonline.com/doi/full/10.10… @KlinPharm

Thrilled to share my Perspective on how #TissueImmunity selectively restrains the growth of metastases - an exciting avenue for developing #Immunotherapies for long-lasting control of #Metastasis Thanks Lucy Bird and @NatRevImmunol for the opportunity! 👉rdcu.be/c4539

Very excited to share our review on "Metabolites as agents and targets for cancer immunotherapy" in @NatRevDrugDisc! read it here: rdcu.be/etAMD @SpringerNature @KlinPharm

Congratulations Simon!

Huge congratulations to Prof. Sebastian Kobold for receiving an @ERC_Research consolidator grant for his project: CATACLIS - Cancer tailored next generation cellular therapies💐@LMU_Muenchen #ERC

#OnlineFirst: Read the In the Spotlight commentary— Unraveling #Tcell exhaustion: genetic screening meets in vitro modeling, by @AlfredZippelius, @MarcelTrefny, @priska_adm, and Schmid describing a recent @SciImmunology paper from the @EJohnWherry group. bit.ly/49iKo2s

We’re excited to present our most recent preprint on bioRxiv “Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer ” biorxiv.org/content/10.110…

Great collaboration with Hutter lab. Philip Schmassmann identifies Sig9 as new target in GBM. #glycotime Targeting the Siglec–sialic acid axis promotes antitumor immune responses in preclinical models of glioblastoma | Science Translational Medicine science.org/doi/10.1126/sc…

The Bassermann lab @TumTransla has several open #positions in #Munich #postdoc tinyurl.com/ywvwyc22 #PhD tinyurl.com/mpxpukt2 and a technical assistant tinyurl.com/2dmm22d8 Are you a science enthusiast, interested in cancer biology and protein turnover grab a seat🍻

We are excited that our latest study on cDC1-mediated coordination of anti-cancer responses by tumor-infiltrating TCF1+stem-like CD8+ T cells, led by @PhilippaMeiser is now published OPEN ACCESS in @Cancer_Cell! cell.com/cancer-cell/fu… 🧵👇1/n

We are thrilled that our recent study lead by @BayerlFelix is out in @ImmunityCP today. We addressed the question how cDC1 dysfunction is regulated in tumors and to which extent this contributes to cancer immune evasion. It is Open Access!👇 cell.com/immunity/fullt… A short 🧵:

Delighted to share our latest research following T cell receptor (TCR) by 3D TEM and showing ectocytosis makes TCR signalling self limiting at the immune synapse. Many thanks to everyone involved. @griffiths_lab science.org/doi/10.1126/sc…

#Koboldlab news: Big congrats to Florian Märkl and @BenmebarekMr and everyone involved @SophiaStock_ @cadilhabl @philippjie @MarrCarsten @BergweltMichael 🍸🍸

New #JITC article: Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity bit.ly/3MJeEuk @NKirchhammer @KarenODixon @AlfredZippelius @MikaelPittet

👇We have a #Postdoc position funded by @EMBO @EMBO_YIP to study tissue-specific immune regulation of metastasis. Come join us in #Lisbon @Neuro_CF @ChampalimaudF 👉Apply: correialab.com/join-the-team/

Very excited to share our work on #resistance to PI3Kα inhibition in #BreastCancer published online today in @CellRepMed 🤩 #OpenAccess 📰 cell.com/cell-reports-m… Summary 🧵👇 1/10

Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia go.nature.com/3Tg3gHY

Eine Forschungsgruppe der @UniBasel hat ein Gen identifiziert, welches T-Lymphozyten in die Erschöpfung treibt. Dies schafft neue Ansatzpunkte für wirksamere Immuntherapien. @DepBiomedicine @snf_ch unibas.ch/de/Aktuell/New…

Targeting SNX9 to prevent CD8 T cell exhaustion and enhance anti-tumor immunity. nature.com/articles/s4146… @MarcelTrefny @AlfredZippelius @DepBiomedicine @NKirchhammer @priska_adm #CancerResearch @natrescancer

Will exhausted immune cells soon no longer be an issue? A research group funded by the SNSF has discovered that inactivation of a gene improves the endurance of #immunecells that tackle #cancer. sohub.io/pq18