Rob Manguso
@MangusoLab
Official twitter of the Manguso Lab @MGHCancerCenter @BroadInstitute @harvardmed, studying cancer immunology using functional genomics and systems immunology
Our latest paper with the Bardeesy lab @MGHCancerCenter out recently in Science. We describe a novel immune MOA for inhibitors of mutant IDH1 involving the upregulation of transposable elements that are sensed by the cGAS-STING pathway. science.org/doi/10.1126/sc… Explainer🧵
Really exciting that @MJWu_TW is opening his own lab close by at @UMassChan ! Amazing science and a great training opportunity for students and postdocs!
Join us! My lab @UMassChan is seeking postdocs and research associates who are passionate about how changes in metabolism and epigenetics contribute to cancer development and immune system evasion. DM me for a chat and apply at ummsjobs.com/job/10593/ (postdoc position)