Martino V. Franchi
@MVFranchi
-Asst Prof (TT) in Human Physiology @UniPadova -Muscle Plasticity in Exercise/Disuse/Aging -EB @jphysiol & @MSSEonline -member SC @E_C_S_S #HumanBeforeScientist
🚨New article from our lab!🚨 -Previous short-term disuse dictates muscle gene expression and physiological adaptations to subsequent resistance exercise- A true collaborative effort! (see the thread below for more) Now out in @JPhysiol physoc.onlinelibrary.wiley.com/doi/full/10.11…
A book chapter we ( @hinksave.bsky.social ) wrote on Sarcomerogenesis and Function. books.google.ca/books?hl=en&lr…
Interested in a pretty cool postdoc project with Dr @HenningLanger and I? 🔥
Hey Muscle And Metabolism Folks on Twitter, @LykkeSylow and I are looking for a Postdoc who is interested in applying for a prestigious @DDEA_Denmark fellowship with us. More details in the picture attached. Please share widely! @MYOTWlTTER
Heather L. Petrick (@UofG_HHNS @NMS_UM) et al. found that #dietary nitrate preserves mitochondrial #bioenergetics and mitochondrial protein synthesis rates during short-term immobilization in mice 🔎 💉 📜 Read the #Research here: buff.ly/KOPkFzU
The Trajectories of Neuromuscular Aging (TRAJECTOR‐AGE Clinical Trial): Study Rationale and Methodological Protocol - Lauretani - Journal of the American Geriatrics Society - Wiley Online Library agsjournals.onlinelibrary.wiley.com/doi/full/10.11…
Mark R. Viggars & Karyn A. Esser (@UFMedicine) present this #TranslationalPerspective on the work of Franchi et al. (2025) into reprogramming metabolic #gene expression during active #recovery following disuse 🧬 🔗 buff.ly/KqOKMs3
Martino V. Franchi (@UniPD_Research) et al. observed that previous short-term disuse dictates muscle #geneexpression and #physiological adaptations to subsequent resistance exercise 🧬 🚴♂️ 📜 Read the #Research here: buff.ly/XHULHXa
Finally out! The first of many on the Trajectories of Aging. agsjournals.onlinelibrary.wiley.com/doi/10.1111/jg… Great team work @HIPE_lab @PorcelliSimone @MVFranchi @re_re84 @marconabacino @c_brusco @MarcoCarbonaro2 @MassimilianoAnsaldo @CaterinaAmendola
Great presentation by @andreapil8 at the ACSM meeting starting from his work on @JPhysiol and then showing some new data. Well done, I am really proud of you 👏💪
Applying lessons from limb muscle disuse and ageing to better understand ventilator-induced diaphragm dysfunction | #Myotwitter | @phc_mesquita et al. @AM_OMRF pubmed.ncbi.nlm.nih.gov/40638619/
Sarcomerogenesis: "sarcomere division is triggered by tension and local sarcomere damage... and muscle contractions. Sarcomere divisions repair damaged sarcomeres, ensure their mechanical integrity, and synchronize sarcomere addition..." @SchnorrerL science.org/doi/10.1126/sc…
🚨 Interested in muscle mechanics? Here you can see our last article about: 👉Regional Heterogeneity in Vastus Lateralis Architecture Influences Fascicle Behavior During In Vivo Contractions @Michele_Trinchi @BizetB_Biomech onlinelibrary.wiley.com/doi/10.1111/sm…
…and I’ll post this by Geoff. I think both tweets by Tony and Geoff are informative for everyone in the field. I know where I stand and I (and some colleagues) have been writing a topical review for quite some time now. I hope to have it ready soon.
It's safe to say my lab is the only active one measuring serial sarcomere number following interventions in rodents CONTEXT MATTERS! if you do not consider the nuanced approach of knee angle/age and dump it all into a metanalysis of course ES is small... Here is what we find:
I’ll post this by Tony and - (see next tweet)
Increasing serial sarcomere number (SSN) and thus fascicle length is highly sought after. Eccentric exercise (ECC) is often thought to be the best stimulus. But is this true? In our review, we pore over 150+ years of data to find out if we’re right tinyurl.com/yc5cjvef 🧵1/14
What an incredible week at @E_C_S_S in Rimini 🇮🇹! Excellent presentations, engaging discussions, and great connections with colleagues and friends. Thanks to @unipd, @unibo, and all the volunteers for making it unforgettable! #ECSS2025 #wearesportscience