MAST Research Program

We're working to build more solutions for conditions of the microbiome - from #IBS and ##SIBO to PCOS and #Diabetes. How can you help? support.cedars-sinai.edu/give/f2127909/…

📰 ICYMI: Our #ENDO2025 abstract is making headlines! We’re excited to see our oral featured in @Medscape, which did an excellent job highlighting our key findings on how hypothyroidism may impact the small bowel #microbiome. The article also includes insights directly from our…

It now seems obvious but a great deal of work went into understanding the role of #methane and #contipation now called #IMO, setting up new drug therapy. Here we present the cause and effect evidence for methane causing constipation from @MASTprogram @CedarsSinai #theMAST5years

MAST’s @MarkPimentelMD is featured in a recent @WebMD article exploring the long-term effects of traveler’s diarrhea & its potential link to #IBS The article highlights his work on how the immune system may mistakenly produce antibodies against vinculin, a human protein, after…

More news from #ENDO2025! 🧠🦠📢 Our research on the link between hypothyroidism and #SIBO was featured in a @TheEndoSociety @EndoMedia press release👏 “These findings open the door to new screening and prevention strategies. For example, doctors may begin to monitor thyroid…

Scenes from #ENDO2025! @CedarsSinai researchers showed up strong this year! Presenting work on the microbiome, hormones, and more. From insightful sessions to a well-deserved visit to the Bark Park 🐶, our team balanced science and smiles @TheEndoSociety @EndoMedia

Kicking off Day 1 of #ENDO2025 with a strong presentation from @CedarsSinai fellow Dr. Margaret Wei! She shared new insights on the link between #SIBO and #hypothyroidism, highlighting the connection between the small bowel #microbiome and endocrine system👩‍⚕️🧠🦠 @TheEndoSociety

Excited to see our research highlighted by @CedarsSinai Newsroom ahead of #ENDO2025! 🎉 @TheEndoSociety Dr. Margaret Wei, Cedars Sinai fellow and collaborator w/ MAST, will be presenting an oral tomorrow on our latest findings linking hypothyroidism & SIBO- a compelling step…

📣 The MAST Program is proud to be presenting 3 posters & 1 oral at #ENDO2025 this weekend! @TheEndoSociety From SIBO and hypothyroidism to metabolic impacts of gut microbes, our team is exploring how GI health and the endocrine system are deeply connected through the…

💭Newest MAST paper! Our latest research shows that breath gas profiles are influenced, at least in part, by small bowel microbial composition 😮‍💨 🤝🦠 📈Higher breath H₂S is linked to H₂S-producing bacteria & is associated with looser stools 💨 Elevated CH₄ is associated with…

What does #WorldMicrobiomeDay mean to those of us at MAST? Let’s find out! 👇 Overall, today is a great chance to spread awareness on the small bowel microbiome & how it impacts different aspects of health and disease Visit our website to catch up on the latest!…

Paper out! Methane and Hydrogen sulfide on three-gas breath test correlate with methanogens and H2S producers in the SMALL INTESTINE! M. smithii for methane and Proteus and Desulfovibrio for H2S, among others. Methane=constipation, H2S the opposite. doi.org/10.1007/s10620…

Most #IBS drug studies focus on what works. But what about harm? We analyzed 54 clinical trials to calculate number needed to harm (NNH) for common IBS meds 🔍 Key: - Rifaximin=safest - Tricyclics, alosetron, tenapanor=highest risk - NNH + NNT=better patient-centered decisions…

Some Wednesday Wisdom from #DDW2025! Throwing it back to MAST's @MarkPimentelMD closing out his ‘SIBO: Hype or Hip?’ presentation with a powerful reminder: #SIBO is real and there is ✨HOPE✨ in the progress being made through research to understand, diagnose, and treat it…

Artificial sweeteners aren’t just in your snacks anymore… they’re in your vape A @nourishbywebmd article investigates neotame, a next-gen sweetener found in many disposable e-cigarettes & ultra-processed foods. MAST physician-scientist @RuchiMathurMD weighs in on the growing…

Today we celebrated an emotional (and fun!) farewell as we sent off Mo, Sepideh, and Dilara on their next big adventures- residency and medical school! Wishing you all the success in this next chapter of your careers. Once a MASTer, always a MASTer! 🫶

In this study, we examine the safety of drugs for #IBS. It turns out that tricyclic antidepressants are among the drugs patients are most likely to stop due to adverse events. journals.lww.com/ajg/abstract/9…

Now in press‼️🚨📢 Adding to the dialogue, the newest evidence-based consensus on perioperative management for patients taking GLP-1 RAs informed by a systematic review of clinical outcomes and gastric emptying data Proud to share that MAST endocrinologist @RuchiMathurMD was a…