Luis Lopes

@LuisRLopes77

Consultant Cardiologist and Associate Professor - Inherited Cardiac Disease and Cardiac MRI- Barts Heart Centre/University College London

London

Joined July 2019

911Following

914Followers

Luis Lopes@LuisRLopes77 · Jul 1

ESC Cardio Genomics 2025, Lisbon 5–6 December. Focus on precision and genetic therapy in inherited cardiovascular diseases. Workshops, lectures and debates. Register now to secure your spot / submit your abstract by 9 September. ow.ly/YWoQ50VzNs5

LuisRLopes77's tweet image. ESC Cardio Genomics 2025, Lisbon 5–6 December. Focus on precision and genetic therapy in inherited cardiovascular diseases. Workshops, lectures and debates. Register now to secure your spot / submit your abstract by 9 September. ow.ly/YWoQ50VzNs5

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Luis Lopes@LuisRLopes77 · Jun 16

Analysis of cardiomyopathy genes in septic cardiomyopathy: tested but did't find the association with rare variants in cardiomyopathy genes present in other "acquired" cardiomyopathies. @RevEspCardiol. would be nice to see data from other groups sciencedirect.com/science/articl…

LuisRLopes77's tweet image. Analysis of cardiomyopathy genes in septic cardiomyopathy: tested but did't find the association with rare variants in cardiomyopathy genes present in other "acquired" cardiomyopathies. @RevEspCardiol. would be nice to see data from other groups sciencedirect.com/science/articl…

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Echo Research and Practice@EchoResPract · Feb 27

🚨NEW ARTICLE🚨 Assessment of myocardial work in sarcomere gene mutation carriers, healthy controls and overt nonobstructive hypertrophic cardiomyopathy: doi.org/10.1186/s44156… @carlammpr @drgeorgejoy @miltosmd @Ksavvatis

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Hunain Shiwani@HunainShiwani · Feb 13

🚀 Excited to share a new tool based on our @JACCJournals study! doi.org/10.1016/j.jacc… 🔍 hcmcalculator.com provides left ventricular hypertrophy (LVH) MWT threshold values and Z-scores based on age, sex, & BSA.

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European Society of Cardiology Journals@ESC_Journals · Feb 11

Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease 💔. A clinical consensus statement of the ESC Council on Cardiovascular Genomics, the ESC Cardiovascular Risk Collaboration, and the European Association of Preventive Cardiology 👉…

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Luis Lopes@LuisRLopes77 · Jan 8

A novel demographic-adjusted personalised approach to measure wall thickness is an important step towards a more accurate / less biased diagnosis of hypertrophic cardiomyopathy. Very glad to be part of this important study led by @HunainShiwani (congratulations!) & @JccmoonMoon

HHunain Shiwani@HunainShiwani · Jan 8

🔬New in @JACCJournals: HCM diagnosis criteria show unexpected demographic bias. Study of 50,000+ hearts reveals current thresholds create 8:1 male-female ratio Proposing demographic-adjusted thresholds to improve diagnosis🫀 authors.elsevier.com/a/1kPE52d9GH~T… @UCL_ICS @NHSBartsHealth

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Luis Lopes@LuisRLopes77 · Dec 18

Reassessment and reclassification of variants of unknown significance in patients with cardiomyopathy jmg.bmj.com/content/early/… - how (and how often) should an ICC department approach VUSes? Work led by our @NHSBartsHealth ICVD genetic counsellors

LuisRLopes77's tweet card. Background The utility of diagnostic genetic testing in cardiomyopathy has grown significantly, due to the discovery of novel genes and greater awareness among healthcare professionals. However, a...

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Luis Lopes@LuisRLopes77 · Dec 9

We analysed mitochondrial variation in cardiomyopathy patients from 100K genomes project and found the HCM causing m.4300A>G in 0.6% of (previously) genotype-"negative" HCM patients humgenomics.biomedcentral.com/articles/10.11… - shall we include it in the testing panels? @RobPitceathly @w_macken

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Luis Lopes@LuisRLopes77 · Nov 25

Promises and challenges of gene therapy in heart failure and cardiomyopathies in a scientific statement of the ESC @escardio HFA, WGMPD and Council on Cardiovascular Genomics onlinelibrary.wiley.com/doi/10.1002/ej…. Pleased to have contributed to this document on an exciting and important topic

EEJHF Editor-in-Chief@EJHFEiC · Nov 25

🗞️ Gene therapy in #HeartFailure : #HFA , @escardio Council on #CV genomics & WG Myocardial & Pericardial Diseases Scientific Statement @ESC_Journals @GiuseppeGalati_ @AmrAbdin10 @HanCardiomd @HFA_President bit.ly/3V9zgzv

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Luis Lopes@LuisRLopes77 · Nov 14

Glad to contribute to this study by @RichardB_KCL @munroe_patsy et al, going beyond imaging of volumes and mass : genetics of biventricular shape. 43 loci, 14 unreported for cardiac. Principal components of shape associate with cardiometabolic disease. doi.org/10.1038/s41467…

JJulia Ramírez@Ju_Ra_Ga · Nov 14

📢Hot off the press! Out latest study investigating the genetics of biventricular shape and their association with cardiovascular disease is just out @NatureComms 👇👇👇 doi.org/10.1038/s41467… @munroe_patsy @alyoung62 @RichardB_KCL

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Luis Lopes@LuisRLopes77 · Nov 2

Arrhythmic risk stratification in ring-like scar (gene negative and positive) academic.oup.com/eurjpc/article… led by Elena Biagini Bologna’s group with interesting results showing primacy of the ECG. Includes London cohort and other collaborators @IacopoOlivotto @AnaRitaMoura5

LuisRLopes77's tweet card. AbstractAims. Left ventricular (LV) ring-like scar on cardiac magnetic resonance (CMR) has been linked to malignant arrhythmias in patients with non-ischae

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Luis Lopes@LuisRLopes77 · Oct 7

Cardio Genomics Conference 2024 December 6-7 in Antwerp, Belgium. Join us for the latest on cardiovascular genomics ! @rbarvil @BondueAntoine @fdefrutossemi @KristinaHaugaa @jpkaski @DAntonakaki @fernidom

EEuropean Society of Cardiology@escardio · Oct 7

Only two days left to save on registration for the Cardio Genomics Conference 2024 happening on December 6-7 in Antwerp, Belgium. Don't miss out on this opportunity to expand your expertise in the field of cardiovascular genomic medicine and connect with peers from around the…

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European Society of Cardiology@escardio · Sep 6

Share your scientific expertise in the field of cardiovascular genomic medicine. The deadline to submit your abstract has been extended to 11 September. Submit today and register to join us in Antwerp on 6-7 December! bit.ly/4d8lyDw #CVD #CardioGenomics…

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Aug 29

Great study on TTR variants in #UKB @LuisRLopesDr jamanetwork.com/journals/jamac… Congrats @DukeCardFellows 🌟@jregan2012 on leading excellent editorial in @JAMACardio & 🙏 @MariannaFonta11 for collaboration! jamanetwork.com/journals/jamac… @DukeHeartCenter @DukeHrtFailure @DukeMPI @Duke_CTSI

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JAMA Cardiology@JAMACardio · Aug 29

Listen to an interview with JAMA Cardiology authors @LuisRLopesDr and @senthil_selv on their recent articles hosted by @sday_hcm. Find the episode on @AMAEdHub. ja.ma/3yXFlai

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UCL News@uclnews · Aug 29

More people in the UK are at risk of a hereditary form of cardiac amyloidosis, a potentially fatal heart condition, than previously thought, finds a new study led by @LuisRLopesDr @UCL_ICS with @QMUL analysing the genes of nearly half a million people ucl.ac.uk/news/2024/aug/…

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Eric Topol@EricTopol · Aug 28

The prevalence of heart amyloidosis related to transthyretin gene variants is higher than expected, Carrier status ~1/1000 overall and ~4% in those with African ancestry. This is an important under-diagnosed and under-treated condition. jamanetwork.com/journals/jamac… from @uk_biobank…

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