Senthil Selvaraj, MD, MS, MA (@senthil_selv)

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Oct 25

Outstanding session @jordy_bc! So much interest in this intersection and more to learn. Kudos to planning committee for fantastic talks. @HeerspinkHiddo @RupalMehtaMD #KidneyWk @ASNKidney

JJordy Cohen, MD, MSCE@jordy_bc · Oct 24

Standing room only at the Kidney Connection to HFpEF session at #KidneyWk!! Extremely high rates of HFpEF in our patients, but as @RupalMehtaMD points out, we have limited data & aren’t looking for this enough @senthil_selv @HeerspinkHiddo

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Jordy Cohen, MD, MSCE@jordy_bc · Oct 24

Standing room only at the Kidney Connection to HFpEF session at #KidneyWk!! Extremely high rates of HFpEF in our patients, but as @RupalMehtaMD points out, we have limited data & aren’t looking for this enough @senthil_selv @HeerspinkHiddo

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Henry Han@HanCardiomd · Oct 18

Towards #Metabolomic-Based Precision Approaches for Classifying and Treating #HeartFailure Personalized approach to metabolomic phenotyping in HF jacc.org/doi/10.1016/j.… @JACCJournals @SvatiShah @KSharmaMD

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Senthil Selvaraj, MD, MS, MA@senthil_selv · May 20

Excellent study linking acoramidis, TTR levels, & mortality in ATTRIBUTE-CM now in @JACCJournals Congrats @jregan2012 on leading our accompanying editorial (bit.ly/436F0i0) & 🙏 outstanding collaborators @MKIttlesonMD @MGKhouri_md @frederickruberg @DukeHeartCenter

senthil_selv's tweet image. Excellent study linking acoramidis, TTR levels, &amp; mortality in ATTRIBUTE-CM now in @JACCJournals

Congrats @jregan2012 on leading our accompanying editorial (bit.ly/436F0i0) &amp; 🙏 outstanding collaborators @MKIttlesonMD @MGKhouri_md @frederickruberg

@DukeHeartCenter

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Circ: Heart Failure@CircHF · May 18

#CircHF Simultaneous Publication with #HeartFailure2025 from @senthil_selv & @VishalNRao et al: Late-Life Echocardiographic Effects of the Amyloidogenic p.V142I Transthyretin Variant Read more➡️ahajournals.org/doi/10.1161/CI… #AHAJournals @MGKhouri_md @AHAScience

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Senthil Selvaraj, MD, MS, MA@senthil_selv · May 18

Led by @VishalNRao, we examined late-life (age 80) echo features of V142I carriers/non-carriers ⬇️ diastolic & LA fxn, progressing over 7 years LA fxn markers uniquely a/w NT-proBNP for carriers Simpub #HFA2025 @CircHF bit.ly/3GZkWWd @DukeHeartCenter @scottdsolomon

CCirc: Heart Failure@CircHF · May 18

#CircHF Simultaneous Publication with #HeartFailure2025 from @senthil_selv & @VishalNRao et al: Late-Life Echocardiographic Effects of the Amyloidogenic p.V142I Transthyretin Variant Read more➡️ahajournals.org/doi/10.1161/CI… #AHAJournals @MGKhouri_md @AHAScience

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JACC Journals@JACCJournals · Mar 29

In KETO-HFpEF, despite robust ketosis, shifting substrate utilization away from carbohydrates, & 📉 estimated LV filling pressures, acute KE supplementation did not improve peak VO2 or constant-intensity exercise in #HFpEF jacc.org/doi/10.1016/j.… #ACC25 #JACCHF @senthil_selv

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Nishant Shah, MD@Nishant_ShahMD · Feb 24

Outstanding @DukeHeartCenter grand rounds with Dr. Sanjiv Shah from @NMCardioVasc on HFpEF management in the age of precision medicine! @HFpEF @manesh_patelMD @jennifer_rymer @texhern @DCRINews @robmentz @DukeHFDoc @senthil_selv @vkittipibul @FudimMarat @SJGreene_md

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Journal of Nuclear Cardiology@JNCjournal · Nov 29

Learn about the most effective interventions to achieve adequate suppression of physiologic myocardial FDG uptake before inflammation/inflammatory imaging. @senthil_selv @dukeheartcenter @pacoebravo @PennCardiology Read now👉bit.ly/3OwKOsM #CVNuc

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Circ: Heart Failure@CircHF · Nov 21

#Editorial - SGLT2 Inhibitors and Their Effect on Metabolism in Patients With Heart Failure ahajournals.org/doi/full/10.11…

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Nov 17

✒️Congratulations to @senthil_selv and @SvatiShah! Dr. Shah directs the Duke Center for Precision Health, and Dr. Selvaraj is a member of the center's leadership team. The center is a partnership with #DukeCTSI and @DukeGenomics.

SSenthil Selvaraj, MD, MS, MA@senthil_selv · Nov 17

Our phase I study of 2 doses of exogenous ketones detailing PK and metabolic profiling in HFrEF by background SGLT2i Simpub #AHA24 & @JACCJournals #JACCBTS jacc.org/doi/10.1016/j.… 🙏 @SvatiShah @MarguliesLab @robmentz @FudimMarat and outstanding team @DukeHeartCenter @DukeMPI

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Ahmed Bennis MD 🫀@drbennisahmed · Nov 17

Metabolic and Pharmacokinetic Profiling of an Exogenous Ketone Ester by Background SGLT2 Inhibitor Therapy in HFREF Hemodynamic effects were transient and irrespective of KE dose or background SGLT2i use, though acidosis was dose-dependent jacc.org/doi/10.1016/j.…

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Nov 17

Our phase I study of 2 doses of exogenous ketones detailing PK and metabolic profiling in HFrEF by background SGLT2i Simpub #AHA24 & @JACCJournals #JACCBTS jacc.org/doi/10.1016/j.… 🙏 @SvatiShah @MarguliesLab @robmentz @FudimMarat and outstanding team @DukeHeartCenter @DukeMPI

senthil_selv's tweet image. Our phase I study of 2 doses of exogenous ketones detailing PK and metabolic profiling in HFrEF by background SGLT2i

Simpub #AHA24 &amp; @JACCJournals #JACCBTS
jacc.org/doi/10.1016/j.…

🙏 @SvatiShah @MarguliesLab @robmentz @FudimMarat and outstanding team

@DukeHeartCenter @DukeMPI

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Ahmed Bennis MD 🫀@drbennisahmed · Nov 10

Metabolic dysfunction: An important driver of incident heart failure with preserved and reduced ejection fraction onlinelibrary.wiley.com/doi/abs/10.100…

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Oct 17

Tremendous job @jregan2012 in leading this piece! 🙏 @SvatiShah for terrific insights on framework, as well as stellar guidance from other dream team co-authors @MGKhouri_md @OpeyemiOlabisi8 @KMAlexanderMD @HeartDocSadiya @JCardFail @Duke_CTSI @DukeCardFellows @DukeHeartCenter

JJessica Regan@jregan2012 · Oct 16

Grateful for the mentorship from this outstanding group of co-authors for our Perspectives piece in @JCardFail Discussing systematic screening for V142I ATTR-CM 🫀 @MGKhouri_md @OpeyemiOlabisi8 @KMAlexanderMD @HeartDocSadiya @SvatiShah @senthil_selv kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Oct 17

We need to consider more systematic genetic screening for risk of hereditary cardiac amyloid & need more data to determine best approach. This has to be done collaboratively w/the community! Read fantastic perspective piece from @senthil_selv @jregan2012 & illustrious co-authors

JJessica Regan@jregan2012 · Oct 16

Grateful for the mentorship from this outstanding group of co-authors for our Perspectives piece in @JCardFail Discussing systematic screening for V142I ATTR-CM 🫀 @MGKhouri_md @OpeyemiOlabisi8 @KMAlexanderMD @HeartDocSadiya @SvatiShah @senthil_selv kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

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Robert Mentz, MD@robmentz · Oct 10

Fun night gathering with the @DukeCardiology HF crew! Can’t beat a beautiful October evening in Durham. Great colleagues - amazing people @DCRINews @DukeHeartCenter @manesh_patelMD

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Senthil Selvaraj, MD, MS, MA@senthil_selv · Sep 25

Thanks @Cornerstone_CME for the opportunity as well as chairs @MasriAhmadMD & team! Big 🙏 to fantastic collaborators @scottdsolomon @SvatiShah @robmentz @MGKhouri_md @HeartDocSadiya @ParagGoyalMD @dr_m_fontana @Richardkcheng2 @DukeHeartCenter @manesh_patelMD @DukeHrtFailure

CCornerstone Medical Education@Cornerstone_CME · Sep 25

#ATTR Young Investigator #Research Award Winner! Dr @senthil_selv from @DukeCardiology will receive $100,000 to further his #amyloid research on the #V142I #transthyretin variant and will speak at our @HFSA symposium in 2025. Many congrats, Dr. Selvaraj!

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