Liling Wan
@LilingWanLab
Assistant Professor @UPenn | Study epigenetics, gene regulation and cancer | views my own
(1/n) excited to share that our study on how condensate-promoting ENL mutations drive tumorigenesis is out at @CD_AACR! aacrjournals.org/cancerdiscover…
Impact of #epigenetic regulator ENL – mutated in childhood #kidney #cancer #Wilmstumour – on developing kidney's gene regulatory landscape before & after birth. Image & research by Lele Song & Qinglan Li et al @LilingWanLab @UPenn in @NatureComms. On bpod.org.uk/archive/2024/7…
bittersweet moment as we send off our absolutely amazing technician, Sylvia, to MD/PhD #WashU and high school student, Samantha, to college @Cornell I chose the book by @kkariko hoping it inspires them to continue breaking through the next chapter of life #proudPI #womeninstem
Mechanisms Underlying Childhood Cancer: Charles Roberts, Mariella Filbin, and Liling Wan will address this topic in a plenary at the AACR Conference on Pediatric Cancer (Sept 25-28; Boston). brnw.ch/21wTSTZ #AACRpediatric25 @TheRobertsLab1 @FilbinMariella @LilingWanLab
Looking forward to sharing our latest work this coming week at Social DNAing!
Are you ready the 2nd half of 2025? Social DNAing is! Checkout who is coming to Social DNAing! Sign up at cancer.columbia.edu/research/progr…. Please re-twitte
Thanks very much @psscra for supporting our work on dissecting how aberrant protein condensates disrupt 3D genome regulation in cancer. Grateful to my team at @LilingWanLab @PennMedicine @PennEpiInst and collaborators who make this research possible. Congrats to all awardees!
The @LilingWanLab is investigating how cancer cells hijack transcriptional condensates to reorganize the 3D genome, aiming to uncover new vulnerabilities in tumor development. Congratulations, Dr. Liling Wan at @PennMedicine! vimeo.com/1085105143
Thrilled to receive the Tony Hunter Award (Junior Investigator) from the Association of Chinese Americans in Cancer Research and to present our work alongside senior awardee Dr. Chuan He. Proud to be part of this amazing community! #immigrant #CancerResearch @PennMedCSO
Attending the #AACR25 Major Symposium on Biomolecular Condensates in Cancer? Read recent work by session chair @LilingWanLab showing that condensate-promoting mutations are drivers of tumorigenesis brnw.ch/21wSk2M
If you are at #aacr25 and interested in Bimolecular condensates and their roles in nuclear compartment, gene regulation, and cancer, come join our symposium on 4/30 focusing on the latest research and concepts on this topic!
Going to #AACR25 this April? I am excited to chair a Major Symposium on biomolecular condensates in cancer-from tools to mechanisms to therapeutics, with talks by Rick Young, Xiaokun Shu @shulab2010, and me. Don't miss it if you are around and interested! abstractsonline.com/pp8/#!/20273/s…
looking forward to sharing our latest work this weekend in Chicago at this exciting symposium chaired by @Ckadoch & Greg Wang, featuring #chromatin #epigenetics in cancer @ASBMB #ASBMB25
Thank you, @ASBMB #ASBMB25 for the opportunity to co-Chair this session with Greg Wang- this symposium will feature an exciting collection of talks and is not one to miss!! 🧬🧫🔬
Going to #AACR25 this April? I am excited to chair a Major Symposium on biomolecular condensates in cancer-from tools to mechanisms to therapeutics, with talks by Rick Young, Xiaokun Shu @shulab2010, and me. Don't miss it if you are around and interested! abstractsonline.com/pp8/#!/20273/s…
Had a great time visiting Dana-Farber Cancer Institute and sharing our work on chromatin mechanisms in cancer! Huge thanks to @JunQiLab for the invitation and generous hosting. So much fun reconnecting with mentor & old friends, making new ones, & a full day of amazing science!
Please Repost- Excited to be recruiting @CeiFccc @FoxChaseCancer #epigenetic #faculty to continue building our energetic, interactive, supportive #collegial environment Our goal- Basic Discovery & help translate to positively impact patients Apply here- jobs.sciencecareers.org/job/665030/fac…
On job market for Assistant Professor position? Check this great opportunity at Penn!
Job Alert!! The UPenn Center for Women's Health and Reproductive Medicine is hiring tenure track Assistant Professors, with a special interest in endometrial biology, gyn cancers, pregnancy and reproductive processes. Apply soon: apply.interfolio.com/153614
Excited to see our paper officially out in the August issue of @CD_AACR !
Condensate-Promoting ENL Mutation Drives Tumorigenesis in vivo through Dynamic Regulation of Histone Modifications and Gene Expression, Yiman Liu, Qinglan Li, @LilingWanLab, and colleagues. @PennMedicine @PennCancer @PennEpiInst @Penn_CBIO bit.ly/4cTwIvw
Having a wonderful time at #acetylation #epigenetics FASEB conference! It started with a tribute to the pioneer of the field, David Allis, followed by diverse topics, great science, and lots of fun interactions in the historic city #Rome #BAHSRC
our preprint is now out @NatureComms! Using genetic mouse models, single cell multiomics, and chemical approach, this study reveals new epigenetic mechanisms linking disrupted embryonic kidney development and pediatric renal tumor (Wilms). full-text access rdcu.be/dNPbC
(1/n) preprint on how Wilms tumor mutations perturb kidney development and how to target this by small molecule! led by Lele Song and Qinglan Li and wonderful collaborators @KSusztak @hao_wu_7 @sasaki_kotaro with input from @KaiTanLab1 @DengYanxiang biorxiv.org/content/10.110…
annual departmental @Penn_CBIO retreat at #skytop beautiful place, great science, and lots of interactions and fun! And, our amazing sophomore Michele found out her acceptance into Flexmed program @MountSinaiNYC medical school!
Congrats @MichaelVOrtiz @oleg8r on a successful meeting that brings patient advocates, physicians, and basic scientists together to advance #pediatric #renaltumors. Such an amazing community! And thrilled to share our work on #epigenetics in kidney development/tumor! #mskkids
The full program for the #Pediatric #RenalTumors Symposium is out! Join global experts @MSKCancerCenter as we explore the latest in biology & clinical research. Plus, exciting networking opportunities. Free registration: bit.ly/PedsRenal #MSKPedsRenalCME @KentsisResearch
Interested in transcriptional condensates and their dysregulation in diseases? Check out our mini-review on recent advances in mechanisms, biological functions, and open questions in this area, led by @kaeli_mathias and Yiman Liu. free access authors.elsevier.com/a/1j8Sx,LqAZbc…
A great pleasure hosting @ChrisVakoc for distinguished cancer series at @PennMedicine . Thank you for sharing exciting discoveries on #transcription #signaling vulnerabilities in human #cancer stemming from elegant CRISPR screens! @ChrisVakoc Gerd Blobel @junwei_s @AsanganiLab
