Biomedical Picture of the Day BPoD

🌪️ Tiny cyclones in a mouse’s eye? In today's @BPoD_s researchers uncovered vortex-like stem cell flows in mouse corneas that sustain ocular surface health. Their models predict these patterns, helping understand corneal renewal ➡️ fcld.ly/5t14fbk made w/ @LeicaMicro

Functional connectivity developing between the cerebellum & cerebrum brain regions mapped in children from birth to aged five 📷 Wenjiao Lyu, Kim-Han Thung & Khoi Minh Huynh et al @UNC in @NatureComms ➡️ bpod.org.uk/archive/2025/7…

#FluorescenceFriday! Thanks BPoD!

Comeback Kidney: Mapping the nerves in the developing kidney 📹 @P_NGUETTA et al @l_obrien_lab @UNC @CellReports ➡️ bpod.org.uk/archive/2025/7… with @DrJohnAnkers

3D-imaging of the mouse skull reveals the effects of ageing on the architecture of nerves & vessels 📷 @AHorenberg et al @GraysonLab @JHUBME in @NaturePortfolio Bone Research ➡️ bpod.org.uk/archive/2025/7…

Stereo Balance: Properly functioning sterocilia – hair-like structures of the inner ear vital for hearing – rely on a precise balance of taperin protein 📷 Inna A. Belyantseva & Chang Liu et al @NIH_NIDCD in @JCellBiol ➡️ bpod.org.uk/archive/2025/7… with @DrJohnAnkers

Analysis of strength, skin temperature & muscle activation in the training of Paralympic powerlifting athletes 📷 Joilson Alves de Souza Leite Júnior et al @ufsoficial, Transilvania University of Brasov & @MTU_ozaledu in @SciReports ➡️ bpod.org.uk/archive/2025/7…

Transcription factors identified that control neuron development – insight for restoring damaged neurons in conditions like Parkinson's 📷@DrGloom et al @perlmannlab @karolinskainst in @Dev_journal ➡️ bpod.org.uk/archive/2025/7… with @DrJohnAnkers

Adherens junction components don't affect the polarity of cells in the fruit fly gut 📷@_CatiaACarvalho Mihoko A. Tame & Daniel St Johnston @GurdonInstitute in @J_Cell_Sci ➡️ bpod.org.uk/archive/2025/7…

A Lost Library found: Patho-DBiT – a way to profile RNA in archival formalin-fixed tissue samples 📷Zhiliang Bai, Dingyao Zhang, Yan Gao, Daiwei Zhang & Shuozhen Bao, et al @Yale @PennMedicine in @CellCellPress ➡️ bpod.org.uk/archive/2025/7… with @AntDLewis

Biochemical tools to rapidly manipulate vimentin intermediate filaments by means of chemicals or light (optogenetics) 📷 Milena Pasolli & @psychescope et al Uni Utrecht, in @JCellBiol ➡️ bpod.org.uk/archive/2025/7…

TREEtment for Heartbreak: DNA sequences called tissue regeneration enhancer elements (TREEs) from zebrafish as potential tissue repair treatment in humans 📷 David W Wolfson et al @Ken_Poss_Lab @DukeRegenerate ini @eLife ➡️ bpod.org.uk/archive/2025/7…

Ingested nutrients activate unique combinations of nerves in the mouse small intestine 📷 Candice Fung et al of TARGID @KU_Leuven in @Nature ➡️ bpod.org.uk/archive/2025/7…

Storm's Eye: Modelling the migration of cells that regenerate the eye's constantly abraded cornea Image made with @LeicaMicro microscopy 📷 Kaja Kostanjevec et al @aberdeenuni @UniLeiden in @eLife ➡️ bpod.org.uk/archive/2025/7… with @DrJohnAnkers

Uncovering the molecules and cells underlying the neuroprotective effects of exercise 📷 Luis Moreira re: Joana F. da Rocha & Michelle L. Lance et al @WrannLab @mghcvrc in @NatureNeuro ➡️bpod.org.uk/archive/2025/7… with @rooph

BMP agonist THR-123 induces new production of β-cells in mice – potential therapeutic approach for insulin-dependent diabetes 📷 Silvia Álvarez-Cubela et al @umiamimedicine in @NatureComms ➡️ bpod.org.uk/archive/2025/7…

Feedback mechanisms involving p21-activated kinase enzymes underlie excitability of a cell's actin scaffold 📹 Joe J. Tyler & Anthony Davidson et al @Cambridge_Uni in @J_Cell_Sci ➡️ bpod.org.uk/archive/2025/7…

Blood cell formation by foetal liver & later, by bone marrow, is differentially regulated by yolk sac cells 📷 @HeyBeyn et al @DanielL84885058 lab @CincyChildrens in @NatureComms ➡️ bpod.org.uk/archive/2025/7… with @AntDLewis

S1PR1 in cells of lymphatic vessels regulates formation of vessel valves & abnormal lymph node-like structures called tertiary lymphoid organs 📷 Xin Geng et al @OMRF in @JExpMed ➡️bpod.org.uk/archive/2025/7…

Crowd Control: The position & shape of cell nuclei influence organ formation (organogenesis) 📹 Lucrezia C. Ferme et al @GIMM_Institute in @ScienceAdvances ➡️bpod.org.uk/archive/2025/7… with @DrJohnAnkers