Lignani Lab

Today is #WorldBrainDay, a global campaign promoting brain health for all ages. At UCL, we're spotlighting some of the groundbreaking research that's shaping the future of brain health and wellbeing. 🧵

2/ Prof Gabriele Lignani of the @LignaniLab_UCL is leading an international team of researchers to develop a new generation of cell-state gene therapies for neuropsychiatric disorders. ucl.ac.uk/brain-sciences…

Our new pre-print "AAV delivery of RNA editing machinery rescues SUDEP and seizure phenotype in a mouse model of Dravet Syndrome" is out! 🧬📷biorxiv.org/content/10.110… @Dr_RKarda @GOSHCharity @DravetUK @DSFeu @UCL_IfWH @_BSGCT

Are you an academic or clinician based in SE England? Interested in joining a new epilepsy network? Let us know - Hub login required tinyurl.com/2ezkvmxe

🚨 New Epilepsy Network in the South East! Four Theme Leads based in SE England are proposing a South East Epilepsy Network for clinicians & academics — potential outcomes: new collaborations, clinical guidelines, a trial registry, all with strong early career researcher…

Postdoc opportunity to study cortical oscillations. It comes with unknown pleasures. Spread the word! url.td/RMdJi

This #EpilepsyWeek, we're excited to welcome world-leading experts to the inaugural Epilepsy Research Institute Conference (22–23 May). We’ll be spotlighting the cutting-edge research driving change in #epilepsy – explore the full programme here: epilepsy-institute.org.uk/conference2025…

Thrilled to share that our latest work on #DravetSyndrome is now out as a preprint! 🚀 This project, brilliantly led by @ClaraZourray and co-supervised by Serena Barral, brought together an incredible team. A huge thanks to everyone involved! shorturl.at/NdC79

What is the next frontier in brain therapy? Small molecules act everywhere; our work targets brain regions with mm precision. Next frontier? Targeting microscale - neuronal connections, ensembles. Here, we test AAV9.retro for noninvasive transduction of neuronal projections.

Please consider applying for the 2025 Gordon Conference on Inhibition and the preceding Gordon Research Seminar on Inhibitory Cascades in the CNS.  grc.org/inhibition-in-……Great lineup

We are pleased to share our new Researcher Directory, featuring the Theme Leads of our six strategic research themes. This directory will be developed to include many more researchers working in #epilepsy and details of key methods used. We hope this will be a valuable resource…

Why academia is sleepwalking into self-destruction. My editorial @Brain1878 If you agree with the sentiments please RT. It's important for all our sakes to stop the madness academic.oup.com/brain/issue/14…

UCL researchers will receive £8.1m in @ARIA_research funding to embark on cutting edge research to help overcome neurodegenerative diseases. @UCLPALS @UCLIoN bit.ly/4g9MN1H

Calling any trainees and early career researchers interested in epilepsy and new drug development - places still remain on this summer's Advanced Epilepsy Course, held in San Servolo near Venice, Italy! ilae.org/congresses/21s…

🚨I’m super excited to announce the teams we’re funding as part of our Precision Neurotechnologies programme.🚨 They’ll work on the next-gen tech that’ll allow us to understand + treat a wider range of brain disorders than ever before. Read more below (1/3)

The Epilepsy Research Institute is pleased to share that three of our theme leads have been awarded significant funding from @ARIA_research. These awards will support potentially transformative projects designed to address some of the most pressing neurological and…

I am looking forward to working with @LignaniLab_UCL and others on this @ARIA_research neurotechnologies grant. A ~$2.5m contribution to our lab's work that will help us make next generation noninvasive brain therapies for specific brain circuits. news.rice.edu/news/2025/rice…

📢Thrilled to announce that our international team has been awarded a prestigious research grant! We aim to tackle some of the most complex neurological diseases using cutting-edge technologies! @roschkoenig @Newrotrash @JerzySzablowski @mikhailshapiro @ARIA_research @UCLIoN

Deadline extend to 19th January!

🚨 Neuropixels Postdoc Opportunity at UCL! 🚨 🌟 Join a cool project to explore epilepsy & neurological disorders with cutting-edge tech. 📍 Based in a friendly, supportive London lab with a great PI. 💡 Great science, and fun team! Apply by Jan 8th. 🔗 tinyurl.com/ycxwhtfs