Laura Edgington-Mitchell
@LauraEM_Lab
Head of the Protease Pathophysiology Lab at the Bio21 Institute, University of Melbourne.
The 13th General Meeting of the International Proteolysis Society will be held in Búsios, Brazil Oct 26-30, 2025. Training workshops will be held at the Instituto Oswaldo Cruz Oct 23-23. Register now! Links below. 1/3
Following #ASCO25, CEO @JSantini1 spoke with ONCOLife to discuss how abenacianine (VGT-309) is shining a light on #lungcancersurgery. ▶️ Watch: bit.ly/44M9vJv #Innovation #OncologyInnovation #Biotech #ThoracicSurgery
Congrats to Anna and Marc for the publication of their review article "Nuclear Roles for Canonically Lysosomal Proteases.' Check it here: tandfonline.com/doi/full/10.10… #LEMLab
#News: Phase 2B VISUALIZE study results will be presented by @PennMedicine’s Dr. Sunil Singhal at #ASCO25, demonstrating that intraoperative molecular imaging with abenacianine for injection (VGT-309) during lung surgery has the potential to improve surgical outcomes. More:…
In a medical milestone, a customized base editor was developed, characterized in human and mouse cells, tested in mice, studied for safety in non-human primates, cleared by @US_FDA for clinical trial use, manufactured as a complex with an LNP, and dosed into a baby with a severe,…
We also show that Coxiella incites the extracellular secretion of lysosomal content in a T4SS-independent manner. A wonderfully enjoyable collaboration with @LauraEM_Lab & @hayleyjnewton labs (with significant mass spec guidance from @Nick_E_Scott!) @TheDohertyInst @UniMelbMDHS
Excited to share this story from my PhD, out today in @NatureComms. We show that Coxiella removes cathepsin B to reduce lysosomal hostility and promote bacterial success. This depends on a vacuole established by effector CvpB. nature.com/articles/s4146…
We’re thrilled to welcome our 14th Snow Fellow, Dr Alisa Glukhova @gl_alisa, a structural biologist from @WEHI_research. Alisa’s work focusses on how cells communicate and what happens when those signals go wrong, leading to diseases like cancer. snowmedical.org.au
Incredibly excited to share Dr Alisa Glukhova has been awarded a prestigious @SnowMedical Fellowship - the only recipient this year! She'll receive $8M over 8 years to advance her groundbreaking #cancer research. Congrats @gl_alisa #medicalresearch 🔗 wehi.edu.au/news/wehi-canc…
Prof. Matthew Boygo, expert in chemical proteomics, to give plenary talk at MCCB 2025! Don't miss this chance to learn from a visionary. 🔗 bit.ly/4hb6pEl #RACI #ozchem #BOD1640
I am happy to share a another manuscript by @BangyanXu, a fun collaboration with Simon and @Thompson_Chem. We report some new sulfoxonium ylide activity-based probes for cysteine cathepsins. Check it out! pubs.acs.org/doi/10.1021/ac…
It's been a big week for this proud supervisor. I am so pleased to announce that @alex_ziegler8 has been awarded the Bill Sawyer Medal, which recognises outstanding achievements of Graduate Researchers in the Dept of Biochem & Pharm. Alex has had a great year and is so deserving!
Super proud of Francesca for delivering an excellent final presentation about her 3rd year project in the #LEMLab. Her actual N-terminomics data matched the quality of her cake! Quite a feat!
We are hiring! Join @VerdoesLab at the @LUMC_Leiden Immunology department to apply chemistry to pioneer the next generation cancer vaccines: linkedin.com/posts/oncode-a…
Happy to share the latest from #LEMLab's @alex_ziegler8 and @bethandersonau in collab with @RLatorre_Dr, @Nick_E_Scott and @dufourlab. We show that legumain is activated during colitis and identify protease substrates in naive and inflamed colon. doi.org/10.1002/jcp.31…
Excited to welcome Stephanie as a new graduate researcher in the #LEMLab. Thanks @ajodonoghue for the recommendation 😀
