RaleighLab
@LabRaleigh
Genomic, biochemical, and cellular drivers of brain tumor heterogeneity and evolution. Cancer predisposition syndromes. Response and resistance to treatment.
Online now from @LabRaleigh alum @last_name_lucas (now @JohnsHopkins), an analysis of #spatial mechanisms underlying #meningioma heterogeneity and evolution: rdcu.be/dIdIV. A collaboration with @HeimbergerAmy in @NatureGenet! @NeurosurgUCSF @UCSFCancer @BrainTumorInst
New from Kanish Mirchia of @LabRaleigh and @SenaOten4 of @HerveyJumper lab, an exciting collaboration with @J_deGrootMD showing that spatial synaptic connectivity underlies oligodendroglioma evolution and recurrence. @NeurosurgUCSF @UCSFCancer @UCSF. researchsquare.com/article/rs-629…
Today is an inordinately important and special day @NeurosurgUCSF.

Very happy to share a new study from @jakeyoung11 that investigates #immune microenvironment reprogramming in #glioblastoma. Tremendous collaboration with many other investigators from @NeurosurgUCSF @BrainTumorInst @UCLAHealth. biorxiv.org/content/10.110…
In Neurosurgery, @RaminMorshedMD, @LabRaleigh, and their colleagues demonstrate that gross total resection correlates with longer local freedom from recurrence across molecular subgroups of meningioma: journals.lww.com/neurosurgery/f… @NeurosurgeryCNS @UCSFCancer @ICOMeningioma
Thanks! A great collaboration with @LabRaleigh @MichaelTMilano @wgbreen @jaydetsky @EricLehrer @HinaSaeedMD @SimonLo21054188 @MarkMishraMD @SahgalArjun @joshuapalmermd and others not on twitter.
A big congratulations to David Raleigh, MD, PhD (@LabRaleigh) on being honored with the Michael McDermott, MD Endowed Professorship! 🎉 @UCSFHospitals @UCSFMedicine @UCSFCancer @ChangLabUcsf @MWMCD
Last night was the single greatest academic honor of my career. Thank you @ChangLabUcsf @MWMCD @NeurosurgUCSF @UCSFCancer @UCSF and so many others.

My PhD work is now out at @elife! Special thanks to @LabRaleigh for making it all possible! doi.org/10.7554/eLife.…
From @LabRaleigh and @TimCaseyClyde in @eLife, a new study of craniofacial epigenetics! We have found epigenetic mechanisms in #meningioma, #schwannoma, and other neural crest tumors. Now, we're trying to understand these in neural crest development. elifesciences.org/reviewed-prepr…
I have struck again #SNO2024… only this time, I have an accomplice who makes my crime, not otherwise specified, a bit more official. And while I’m incriminating people, @last_name_lucas took the pic.

We're looking forward to connecting with our colleagues at #SNO2024! Check out the list of presentations from our team of researchers: buff.ly/3ZhTeuk @UCSFCancer @HerveyJumper @LabRaleigh @ManishKAghi @jakeyoung11 @josephcostell14 @VasuLabUCSF @Dr_PViswanath @bnamdphd
Pre #SNO24 sports tradition with @last_name_lucas continues with @HoustonRockets!!

Literally the first person to #Vote2024 at the polling place around the corner from my house in #SanFrancisco this morning. Brought my two kids and spent a long time talking about the importance of this process. No, my facial hair choices are not on the ballot.

An absolute joy to learn from @adrienne_boire from @MSKCancerCenter at @UCSFCancer today. There is no substitute for creativity and drive in this business, and Adrienne exemplifies both and so much more.

So excited to be part of this team (and to share my first publication from Genentech)! 🎉 How can you keep cell perforating proteins silent? Read on to find out! Link: rdcu.be/dYAXc
Thrilled to share our findings on NINJ1 autoinhibition, now online in @Nature. Big thanks to the amazing team @dixitvishva @Melissa_Truong @DrMCJohnson @AlexisRohou and many others. Video by the talented, twitterless Sergei Pourmal (1/3)
This week, Nov 1st at 4pm: Neuro-oncologist Adrienne A. Boire, MD, PhD, @MSKCancerCenter presents "Fortune Favors the Bold: Cancer in an Extreme Microenvironment" at our @ucsf Friday Seminar Series in Basic and Translational Research. ow.ly/v5p650TTJa3
excited to share COMET! A scalable CRISPR approach we (@carwils) developed to identify multidomain proteins that modulate transcription at specific endogenous genomic loci. @arcinstitute @ucsf doi.org/10.1101/2024.1…