Minguet_lab (@LabMinguet)

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Minguet_lab@LabMinguet · Nov 6, 2023

T cell friends! CAR T cell aficionados! Here a quiz for you! The TCR have four signalling chains, the CAR uses only one, which one do you think will perform best?

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Mahima Swamy@MahimaSwamy · Nov 19

Had a great visit to the Kennedy Institute at Oxford yesterday- thanks @AGerardLab for hosting me!

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Kennedy Institute of Rheumatology@KirOxford · Nov 15

On Monday 18th Nov, Dr Mahima Swamy joins us to talk about "The multiple roles of intraepithelial T lymphocytes in maintaining intestinal homeostasis". Don't miss it! Oxford Talks: talks.ox.ac.uk/talks/id/c51b1…

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Roger Federer@rogerfederer · Nov 19

Vamos, @RafaelNadal! As you get ready to graduate from tennis, I’ve got a few things to share before I maybe get emotional. Let’s start with the obvious: you beat me—a lot. More than I managed to beat you. You challenged me in ways no one else could. On clay, it felt like I…

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Minguet_lab@LabMinguet · Nov 18

Excited to read this paper on the changes in the gut upon ageing

NNiharika Duggal@Duggal_UoB · Nov 16

Our new paper on the role of Age-related loss of intestinal barrier integrity on T cell ageing is published in Ageing Cell! A massive thank you to@MsMacrophage @GAnderson808 @WvSchaik @ClaudioMauro6 and amazing team @jessicaconway_ doi.org/10.1111/acel.1…

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Minguet_lab@LabMinguet · Nov 14

Congratulations Jan! What a year, your are rocking it!

JJan Böttcher@JBoettcherLab · Nov 14

Excited to share that our story on PGE2-mediated control of NK cell metastasis surveillance in lung tissue is now published in @CellReports 🤝 Thanks to the many great colleagues who helped conduct this study! 👏Congratulations to first author @AMPedde! cell.com/cell-reports/f…

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Minguet_lab@LabMinguet · Nov 11

Interesting and important.

FFelix Drost@DrostFelix · Nov 11

1/10 PREPRINT MONDAY at the SchubertLab Benchmarking TCR-Epitope Predictors with ePytope-TCR (doi.org/10.1101/2024.1…) Short-Summary: - 18 pre-trained public methods - evaluated on 2 benchmarking datasets - for repertoire annotation & cross-reactivity prediction

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Minguet_lab@LabMinguet · Nov 12

Wow, thanks Chenqi for sharing, as always, interesting, insightful and fun to read!

CChenqi Xu@ChenqiXuSH · Nov 12

We are happy to publish a perspective @NatRevImmunol, focusing on a charge-based signaling motif BRS. Being widely present in immunoreceptors and other membrane proteins, BRS can regulate many aspects of immune responses. nature.com/articles/s4157…

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Chenqi Xu@ChenqiXuSH · Nov 12

We are happy to publish a perspective @NatRevImmunol, focusing on a charge-based signaling motif BRS. Being widely present in immunoreceptors and other membrane proteins, BRS can regulate many aspects of immune responses. nature.com/articles/s4157…

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Stefan A. Rensing@RensingStefan · Nov 8

On the way back to @UniFreiburg after the @CIBSS_UniFR review @dfg_public - after being focused on this event for months, time to be a little unfocused or shift the focus to other things.

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SFB1160@sfb1160 · Nov 5

‼️ Don't miss the next Immunity & Infection #seminar on Monday, November 11, 2024 with Prof. Dr. Christina Zielinski @sfb1160

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Lydia Lynch@lynchielydia · Oct 31

Delighted to share our paper on adipose gd T cells making IL-17 every night for homeostasis, coordinating lipid metabolism after eating @Nature Huge effort by @Akaron0884 & @BrennethS and the team and collaborators to work this out. Aaron's Tweetorial 👇 nature.com/articles/s4158…

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Minguet_lab@LabMinguet · Oct 31

Our new work led by our fantastic PhD student Jose (@j__cabezas) showing dramatic reductions in TCR-T cell cross-reactivity without modifying the TCR. Part of this work relied on SPR-based @carterra_bio to measure 163 TCR/pMHC affinities within 24 hours at 37 degrees.

JJose Cabezas-Caballero@j__cabezas · Oct 31

I am excited to share the results from my PhD project at the @Dushek lab and my first first-author manuscript! Generation of T cells with reduced off-target cross-reactivities by engineering co-signalling receptors. biorxiv.org/content/10.110… 🧵

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Minguet_lab@LabMinguet · Oct 27

Just over 2 weeks left to apply! Our highly collaborative and interdisciplinary Cluster of Excellence is looking for a new colleague with expertise in #cryoEM #structuralbiology and #signaling #facultypositions #professorship

CCIBSS@CIBSS_UniFR · Oct 8

🚨 #JobAlert: W3 Professorship in Physical Chemistry with a focus on Cryo-Electron Microscopy. Join the Faculty of #Chemistry and #Pharmacy @UniFreiburg and contribute to cutting-edge research in the Cluster of Excellence #CIBSS. Apply by Nov 12, 2024! 👉 uni-freiburg.de/stellenangebot…

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Minguet_lab@LabMinguet · Oct 23

Come work with me at the @MedUni_Wien - I have a PhD position open which investigates CAR T cell downstream signaling!

MMedUni Wien@MedUni_Wien · Oct 23

#PhDCall 2024: Optimise #CARTcells like a #lego model! 🧬⤵ In one of our PhD projects, you can optimise the signalling pathways of CAR T cells - just like a lego model! Read more and apply now! ➡ bit.ly/3ZK6bOg @ZajcCharlotte

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MedUni Wien@MedUni_Wien · Oct 23

#PhDCall 2024: Optimise #CARTcells like a #lego model! 🧬⤵ In one of our PhD projects, you can optimise the signalling pathways of CAR T cells - just like a lego model! Read more and apply now! ➡ bit.ly/3ZK6bOg @ZajcCharlotte

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Minguet_lab@LabMinguet · Oct 22

Happy to hear your thoughts about this perspective! Do you think there is still space for further improvements?

WWaggoner Lab@LabWaggoner · Oct 22

REVIEW @NatRevImmunol From TCR fundamental research to innovative chimeric antigen receptor design nature.com/articles/s4157…

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Minguet_lab@LabMinguet · Oct 21

Excellent review from the lab about CAR design 😍 Look inside 👀

MMinguet_lab@LabMinguet · Oct 21

Do you know how to design innovative CAR T cells? The TCR is an incredible inspiration and has tons to teach us! Check our latest perspective in Nat Rev Immunology: rdcu.be/dXDkG You will find a new exciting way to look at CAR T cells! @CIBSS_UniFR @BUnifr @UniFreiburg

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Minguet_lab@LabMinguet · Oct 21

Do you know how to design innovative CAR T cells? The TCR is an incredible inspiration and has tons to teach us! Check our latest perspective in Nat Rev Immunology: rdcu.be/dXDkG You will find a new exciting way to look at CAR T cells! @CIBSS_UniFR @BUnifr @UniFreiburg

LabMinguet's tweet image. Do you know how to design innovative CAR T cells? The TCR is an incredible inspiration and has tons to teach us! Check our latest perspective in Nat Rev Immunology: rdcu.be/dXDkG You will find a new exciting way to look at CAR T cells! @CIBSS_UniFR @BUnifr @UniFreiburg

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yEFIS@y_efis · Oct 17

📣 Join us for the yEFIS General Assembly on 🗓️ November 12, 2024, at 5 PM CET via Zoom. 🧑‍💻 ✨ Connect with over 850 young immunologists, meet our task force, and discover upcoming activities and opportunities. 🔗 Register now: tinyurl.com/yEFIS4thGA (limited spots available!)

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Jurgen Kuball@JKuball · Oct 18

Amazing session at ⁦@_CTGCT_⁩ with ⁦Jane Kinghorn UCL and Heiko van der Leyen in Ljubljana on how to make translational medicine in ATMP development more efficient and attractive to a next generation of researchers, regulators and investors.

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