Lydia Lynch
@lynchielydia
Professor, Princeton University. Immunologist, Irish Mammy, Optimist
Comp bio postdoc positions available! Come work with us @Princeton on computational method development and applications in regulatory genomics, genome editing, immunology and cancer, in mouse and human: pritykinlab.github.io/#jobs Please share among all those who may be interested!
We are pleased to announce that Ulrich H. von Andrian, of @HarvardMed, is AAI's 2025-2026 President! "Looking ahead to the 2025–2026 term, my vision is rooted in three guiding principles: empowerment, community, and stewardship," said Dr. von Andrian. 🔗 ow.ly/wJ3G50WjbYx
“We’re going to use Micromap to shine a light on the biology of certain types of cancers in ways that people have not been able to do before." @princetonchem professor @dmac68 and newly named Distinguished Scholar to the Ludwig Princeton Branch of @Ludwig_Cancer:…
So exciting for our Ludwig Princeton Branch to have Dave Mac Millan join us! DreamTeam 🤩
David MacMillan @MacMillan_Lab, professor of Chemistry, named Distinguished Scholar to the Ludwig Cancer Research Princeton Branch opening a new chapter for the Macmillan lab. He joins MolBio faculty Yibin Kang @yibinkang and Lydia Lynch @lynchielydia. princeton.edu/news/2025/06/1…
Even in the rain, @Princeton is beautiful. #standupforprinceton 🐅

New review on the promise of gd T cells in cancer and immunotherapy nature.com/articles/s4156…
So exciting for our Ludwig Princeton Branch to have Dave Mac Millan join us! @dmac68 @MacMillan_Lab @Ludwig_Cancer DreamTeam 🤩
David MacMillan has been named Distinguished Scholar to the Ludwig Princeton Branch of @Ludwig_Cancer, opening a new chapter in cancer research for the @MacMillan_Lab. Announcement from @PrincetonChem: bit.ly/4kVBqxc
David MacMillan has been named Distinguished Scholar to the Ludwig Princeton Branch of @Ludwig_Cancer, opening a new chapter in cancer research for the @MacMillan_Lab. Announcement from @PrincetonChem: bit.ly/4kVBqxc
Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j3xGs8
Congratulations Yu-San 🧫🧪🧬 We ❤️ gd T cells!
I am so excited to share our new publication on Nature Metabolism about the metabolic reprogramming in gdT in response to inflammation. #gdt #immunometabolism Thanks for my research team in group @Tim_Sparwasser in Germany and Princeton @lynchielydia 🙌🏻
Our paper @SciImmunology shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy success in ovarian cancer. Wonderful to collaborate with @donalb5 again, Marcia Haigis & super postdoc @_Karen__S_
Scientists have uncovered how abdominal fluid called ascites in patients with high-grade serous #OvarianCancer suppresses antitumor cytotoxicity in #NaturalKiller cells. @lynchielydia @_Karen__S @donalb5 Learn more in Science #Immunology: scim.ag/43uqCz9
A study in @Nature provides evidence in mice that cold memory can alter whole-body metabolism, suggesting that memory recall alone can influence temperature regulation and metabolic activity. go.nature.com/4jnKj26 go.nature.com/3GsY29k 🔒
Congratulations @LabVousden
Congratulations to Scientific Editor Karen Vousden, winner of the #AACR25 @AACR-G.H.A. Clowes Award for Outstanding Basic Cancer Research! Her award lecture will be held on Monday, April 28, at 5:30pm CT in Room S404.
And Tomas’s paper was another example of global collaboration 😊
Neuroscience is collaboration. The engram/metabolism combination couldn't have happened without our partners - especially @lynchielydia @lynchlab (now at @Princeton, formally @harvardmed & @tcddublin). Also @DrChristineAnnD at @ColumbiaMed, and @Clrar (now at @ujaen).
And news and views on the paper 🐭📝❄️
Neurons involved in forming memories of a cold environment communicate with the part of the brain that regulates metabolic responses to cold stress go.nature.com/4iAvW9A
Delighted to have taken part in this project that was published today led by Tomas Ryan’s lab @TJRyan_77 @tcddublin @tcdTBSI ….. mice remember cold 🐭📝❄️
Immunologists and neuroscientists collaborate to show that the experience of cold temperatures leaves a lasting impression on the brain, from today's Nature paper by the labs of Princeton's Lydia Lynch @lynchielydia and Trinity College Dubin's Tomás Ryan. molbio.princeton.edu/news/2025/cold…
Announcing the launch of the Weill Cancer Hub East, bringing together experts from @Princeton, @RockefellerUniv, Weill Cornell Medicine and @Ludwig_Cancer to innovate cancer treatment, supported by a generous donation from the Weill Family Foundation. bit.ly/420TcHv
This is a super exciting and striking finding by the @EileenWhitePhD lab on the role of CCL2 in cachexia
Autophagy Suppresses CCL2 to Preserve Appetite and Prevent Lethal Cachexia biorxiv.org/content/10.110…