Sean Jurgens

Excited to share our recent work on cross-biobank and pan-ancestry genetic analyses of rare variants for human disease 🧬 published last week in @NatureGenet @xxinxwang @patrick_ellinor Link: nature.com/articles/s4158…

Two new papers in @NatureGenet from @patrick_ellinor and team Expanding genetic discovery of rare, structural and common variation in atrial fibrillation Sequencing >50K cases nature.com/articles/s4158… GWAS >180K cases nature.com/articles/s4158…

Atrial fibrillation is far more heritable than generally perceived. Two new reports @NatureGenet identify many more linked genomic variants and a refined polygenic risk score @patrick_ellinor nature.com/articles/s4158… nature.com/articles/s4158…

Now on medRxiv, we explore the genetic similarity between dilated cardiomyopathy (DCM) and peripartum, alcohol-induced, and cancer therapy-related cardiomyopathies (PPCM, ALCM, CCM). Led by star trio @DimitriMaamari, @kiranbiddinger, and @JurgensSean. medrxiv.org/content/10.110…

In a new study, @MGHHeartHealth researchers and collaborators identified genetic variants associated with common cardiac rhythm disorders. The findings are published in @NatureGenet. Read more: massgeneralbrigham.org/en/about/newsr… doi.org/10.1038/s41588… @luchenweng @joeltramo @jurgenssean…

Is slow heart rate or conduction block heritable? Check out our new meta-analysis @NatureGenet incl common (~1.3m individuals) + rare (~400k) variants for bradyarrhythmias and conduction dz. Co-led w/ @LuChenWeng @joeltramo @JurgensSean @broadinstitute ! nature.com/articles/s4158…