Jessica Sacher, PhD
@JessicaSacher
Scientist @Stanford | Cofounder @PhageDirectory | Host of Podovirus 🎙
Does every scientist need an AI co-scientist? We sat down with @jrpenades & @CostaT_Lab, two @imperialcollege professors putting @google's new 'AI co-scientist' tool to the test. How long did it take AI to solve the mystery they'd spent a decade trying to figure out? 🧵

This is why Older Millennials are the only truly sane generation who has ever lived, or probably will ever live
Millennials are the only generation that have any sort of notion that you’re not just supposed to believe anything you see on the internet
Huh. I wonder why?
Scientists overwhelmingly recognize the value of sharing null results, but rarely publish them in the research literature go.nature.com/472poOC
This is why I stopped working on AI + spreadsheets lmao
Amazing. First really useful AI integration by Google.
I realized we hadn’t cast a wide enough net for this role originally. If you’re a student or recent grad looking to get away from the bench but want to be deeply integrated into a fast-paced research environment with a front row seat into the operations of a new type of science…
Is anyone routinely using @plasmidsaurus for lytic, tailed, dsDNA phage sequencing? How much DNA are you sending?
Zymo sent me an email for an upcoming webinar they are hosting called "Advancing Long-Read 16S rRNA Metagenomics: Workflow Innovations for Robust Results". NO!!!!! 16S rRNA amplicon work is NOT metagenomics!!!!!!!!!
George Church surprising (and inspiring!) takes from the @dwarkesh_sp pod - no law of physics stops gene delivery to every cell - genetic counseling is under-hyped and sees it similarly to gene editing - he believes that replacement theory of the brain is plausible - he’s…
Awesome new offering from Ginkgo Datapoints -- we will price match any ADME service quote you get (including from Chinese or other international vendors). We plan to have the best per-compound pricing out of the gate anyway --our automation at Ginkgo allows best in class…
We’re excited to launch a powerful new capability at Ginkgo Datapoints: high-throughput, low-cost ADME profiling—optimized for machine learning from day one. Whether you’re prioritizing small molecules or training predictive models, early access to rich ADME data can…
The first pivotal, FDA-enabling clinical trial of a longevity drug is now fully enrolled We will monitor these dogs for the next ~4 years, quantifying millions of data points across biological changes, quality of life, disease, + lifespan
1,300+ dogs. 72 clinics. One giant leap toward the first FDA-approved lifespan extension drug for dogs. The STAY study is fully enrolled!
I try not to get caught up in all the LLM hype... but is Kimi actually, genuinely a very good writer? Do we really have a contender to Sonnet and Opus' writing prowess, and it's open source, no less?
Swap your tool calling model to Kimi K2 on Groq for better results, instantly.
Kimi K2 is **INCREDIBLE** at using tools. I built a chrome extension to chat with Google Maps, but I never posted it. All the models kept screwing up. I just replaced them with Kimi K2, and watch it easily plan an epic wine and food tour around Napa Valley for my bday!…
Kimi K2 is **INCREDIBLE** at using tools. I built a chrome extension to chat with Google Maps, but I never posted it. All the models kept screwing up. I just replaced them with Kimi K2, and watch it easily plan an epic wine and food tour around Napa Valley for my bday!…
Elad Gill refers to this all the time - 1 big mega tech >> entire pharma market size. I think it has a lot to do with the structural differences. In pharma, the product comes with the expiry date (loss of patent protection) that breaks the true compounding of the asset.
Although I am very pro-automation, I often roll my eyes when I see people talk about “automating science” in biotech Any serious conversation here needs to consider the way new methods are invented and scaled
People who are passionate about automating science should consider challenging themselves to move earlier in the innovation cycle Who will be the first team to develop a 0-to-1 technique natively on a robot for the first time? Who will make a robot that can cook?
Millions of Americans are living with the damage caused by strokes and traumatic brain injuries. Today we launched a program in ARPA-H to restore function to the neocortex.
NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…
Wow... The FDA just posted an archive of Complete Response Letters from 2020-2024 open.fda.gov/apis/other/app…