Janice Mehnert, MD
@JaniceM10
AD Clinical Research;Tenured Professor;Phase I,Melanoma/Skin Cancer;ECOG Melanoma Co-Chair.Wife/mom/actress.Love Monmouth County. Tweets mine.Equity advocate.
No time like ASCO eve for an announcement. As of July 1, I will be joining the Perlmutter Cancer Center of NYU as the Associate Director for Clinical Research. I will continue my work in phase 1 trials as well as my focus on melanoma and skin cancer.
Strong work @Perlmutter_CC @NYULH_RadOnc @JaniceM10
Congratulations and thank you to our NRG top accruing sites at #NRG2025 this round! 👏👏 @IndianaUniv @UPMC @aboutKP
This important work provides an opportunity for us leaders in clinical research to be nimble and innovative. We must develop strategies to expand clinical trial offerings. As I tell my team clinical research is no longer “extra credit” - it’s state of the art cancer care.
Exciting new abilities to extend clinical trials and innovative therapies across the growing UNC Health cancer network from the mountains to the coast!
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Check out the top 5 OncLive videos under 5 minutes right here, including insights from @JaniceM10, @TaliAzen, and others! See more here: hubs.li/Q03x8tKd0
There is no greater pleasure than watching one of your mentees achieve this stellar career milestone!
Excited to share that we have been awarded $23.7 million grant from ARPA-H ADAPT program to investigate mechanisms of resistance & new therapies for IO resistant NSCLC! Honored to be PI on this with our leader @DrRaviSalgia #AritroNath cityofhope.org/city-of-hope-a…
Excited to have been a part of this work, led by Dr. Kirchhoff and Dr. Monson.
Why do some melanoma patients respond to immunotherapy while others don’t? Our new study links inherited mitochondrial DNA differences to treatment response, offering insights for personalized cancer care. ✍️ @Nature @Perlmutter_CC 🔗 Read more: nature.com/articles/s4159…
I presented data from our trial of ipi, nivo, rela and IL-6 receptor inhibitor sarilumab in metastatic melanoma. Improved response rate, and toxicity way down!Now confirming in a randomized cohort +/- sari.A patient-centered approach addressing both efficacy and tolerability.
Exciting data presented this morning by Janice Mehnert, MD (@JaniceM10) from NYU Langone Perlmutter Cancer Center. Phase II results of sarilumab in combo with ipi/nivo/rela in advanced melanoma showed a 12.1% grade 3-5 irAE rate and a 63.6% response rate at 24 weeks. #Melanoma
Amazing representation of @nyulangone @Perlmutter_CC at #ASCO25 @JSabari @JaniceM10 @PeterYuMD @kccsehak @ElaineShumMD
He departed from his new wife to serve in Africa, France and Germany. His service earned two Purple Heart awards. I am in awe when I think of the sacrifice. I was nine when he died, but I remember his stern, yet loving nature. I would give anything to see him. Thank you,Grandpa.

Congrats to Teru and @AmruteshPuranik on fine work! Mentoring this team brings me much joy.
Thank you to Teruyuki Mizutani, of @nyulangone, who stopped by during #AACR25 to discuss B-cell subtype as a biomarker for combination therapy in stage III-IV melanoma! See our site for more from the meeting! @AACR #melsm #oncology onclive.com/conference/aacr
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The moment! Transfer of @AACR presidency from one *AMAZING* leader, clinician, and human being to another. @AACRPres Dr. Pat LoRusso —> Dr. Lillian Su. Thank you, Dr. LuRusso, for your service. Look forward to working with you, Dr. Su! #AACR25
Very exciting work, Phase 3 open now at @Perlmutter_CC - first site in New York/NJ!
Extremely excited re: IMA203 - PRAME TCR T cells Ph 1 study published in @NatureMedicine! This is a transformative Rx in #melanoma for HLA-A201+ & PD1 refractory pts. Compared to TIL, easier to make, less toxic & so far ~2x response rate in heavily pre-Rx. nature.com/articles/s4159…
Our published experience below from @Perlmutter_CC in melanoma brain metastases. Outcomes of concurrent versus non-concurrent immune checkpoint inhibition with stereotactic radiosurgery for melano… pubmed.ncbi.nlm.nih.gov/40183901/
Thank you @Seamusoreilly18. I miss him terribly but I am grateful for the lessons he taught me in life and leadership.
Why mentorship matters 👇 Beautifully ✍️ & insightful tribute by @JaniceM10 @nyulangone about her mentor Jeffrey S. Weber: 1952–2024 aacrjournals.org/clincancerres/… Multiple pearls of wisdom including: How to lead The importance of being generous with ⏱️ The impact of mentoring
I enjoyed working with this team to publish our experience in skin toxicities from cancer immunotherapy. @nyugrossman Characterizing Chronic Cutaneous Immune-Related Adverse Events Following Immune Checkpoint Inhibitors pubmed.ncbi.nlm.nih.gov/40072456/
Thanks @MayoClinicHS for inviting me to talk about one of my favorite topics, neoadjuvant therapy for the treatment of melanoma.

Another important analysis led by @MattCarlino featuring contributions from our team @Perlmutter_CC. Outcomes following long-term disease control with immune checkpoint inhibitors in patients with advanced melanoma pubmed.ncbi.nlm.nih.gov/39667250/
Saved the wine generously gifted by @PAscierto to go with our seven fishes for an Italian Christmas Eve. Merry Everything to Everyone.

I always enjoy publishing with @MattCarlino and crew! Outcomes following long-term disease control with immune checkpoint in... sciencedirect.com/science/articl…
I always come back feeling refreshed. Thank you @PAscierto for your vision in forming the Bridge.
Traveling home from the 2024 #ImmunotherapyBridge and #MelanomaBridge meetings in Napoli. We came, we ate/drank ALL the food/wine, we debated, we collaborated, and we strengthened our community. I even got to debate one of my #she-roes @Chrystal_Paulos. Every year, this meeting…
Au contraire, my friend. You are standing right where you are meant to be.
Honored to be under qualified for this award. Will continue to push to reach the commitment and contribution of past recipients.