Prof. Jamie Rossjohn
@Jamie_Rossjohn
Welsh & Australian. FAA FAHMS FLSW FMedSci FRS
Nature research paper: Dual regulation of mitochondrial fusion by Parkin–PINK1 and OMA1 go.nature.com/4bj2UJp
From Kane: Malissen et al (hubs.la/Q03s_K-k0) report that a gain-of-function mutation in CARMIL2 is sufficient to replace the contribution of CD28 to NF-κB activation & downstream effects in T cells, including in the setting of an anti-tumor response hubs.la/Q03s_HDP0
Will be delighted to welcome you in Oxford! Join us to explore where Immunology meets AI. Abstract & Hackathon deadline: 27 June Apply now — scan the QR code! #Tcells #AI #Immunology #Oxford #Hackathon
Congrats to Hien, 1st author of this study that arose from her hard work during her PhD.
Latest research from @jbiolchem “The molecular basis of T cell receptor recognition of citrullinated tenascin-C presented by HLA-DR4” by Dao et al. jbc.org/article/S0021-… @ASBMB @Jamie_Rossjohn
🌟 Announcing the 2025 Fellows of the Australian Academy of Science 🌟 We are proud to welcome 26 exceptional scientists as newly elected Fellows. Their work spans mental health, food security, theoretical physics and more—showcasing the exceptional breadth and depth of…
We’re proud to share that four Fellows of the Australian Academy of Science have been elected to the @RoyalSociety—one of the highest honours in science. Among this distinguished group is Professor Chennupati Jagadish, President of the Academy, who has been elected as a Fellow…
In collaboration with Moody lab, latest paper from @RossjohnLab describing the structure of a lipopeptide bound to a MHC-I like molecule found in chickens - hopefully this study will not ruffle too many feathers.
Mitochondria produce nucleobase ligands for T cells. Our recent paper was published today in PNAS. @Jamie_Rossjohn @Jamie_Rossjohn Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells pnas.org/doi/10.1073/pn…
Our paper @SciImmunology shows certain lipids are responsible for the immunosupression of ascites & propose blocking lipid uptake thru SCARB1 may help immunotherapy success in ovarian cancer. Wonderful to collaborate with @donalb5 again, Marcia Haigis & super postdoc @_Karen__S_
Scientists have uncovered how abdominal fluid called ascites in patients with high-grade serous #OvarianCancer suppresses antitumor cytotoxicity in #NaturalKiller cells. @lynchielydia @_Karen__S @donalb5 Learn more in Science #Immunology: scim.ag/43uqCz9
Introducing your 2025 Stawell Gift Winners! 🏆 In an edition for the ages, Bree Rizzo has stormed to victory from scratch at the Stawell Gift while Adelaide school teacher John Evans pulled off what many didn’t think was possible in one of the hottest fields in years to claim…
Your immune system gradually loses it top team players when we get older 👱➡️👵 Our study in @eBioMedicine investigates how long our good immune cells stay around – a 🧵⬇️ go.unimelb.edu.au/4sep @CvandeSandt @KatherineKedz @TheDohertyInst #Influenza #AgingResearch
Recent paper from lab describing a peptide-independent MHC-restricted T cell receptor nature.com/articles/s4146… in collaboration with La Gruta lab @MonashUni @Monash_FMNHS @RossjohnLab @NatureComms
Meet our newly appointed Deputy Directors! Prof @FZMarques (Discovery), A/Prof Nitesh Nerlekar (Clinical Research), and Prof @DominiqueCad (Health Systems) will provide strategic direction and research expertise across the translational spectrum. More: bit.ly/3DovMmX
Thank you for your support.
For three years Australia has proudly supported the brave people of Ukraine in their struggle to defend their sovereignty against the brutality of Russian aggression and in support of international law. Australia stands with Ukraine. 🇦🇺🇺🇦
From the roads of Tokyo 🇯🇵🇯🇵 Jessica Stenson has climbed to third on the Australian all-time list with a stunning 2:22:56 to finish in 10th place at the Tokyo Marathon, nailing the World Championships qualifying standard of 2:23:30! Paralympic star Madison de Rozario claimed…
A new study in mice shows that associations between LCK and #Tcell coreceptors ensures fidelity of MHCI- and MHCII-restricted T cells to #CD8 and #CD4 lineages, respectively. @Jamie_Rossjohn @PiroozZareie @NicoleLaGruta1 scim.ag/4k8yBcj
LCK-mutant mice help define the role of LCK–co-receptor association in T cell development and immune responses @SciImmunology @NicoleLaGruta1 @PiroozZareie @Jamie_Rossjohn @RossjohnLab science.org/doi/10.1126/sc…
Researchers report in a new Science study that a mantis shrimp’s dactyl club has phononic bandgaps in which stress waves of specific frequency ranges are filtered. This demonstrates that natural materials can exhibit phononic behavior that is observed in artificial…
Researchers in Science #Immunology have identified CD8+ T cells from human donors that can recognize naturally occurring influenza variants spanning more than 100 years, including the 1918 influenza A and 2024 #H5N1. @Jamie_Rossjohn @kedzierskalab scim.ag/4hpSzh1