Claudia Höbartner
@HoebartnerLab
Nucleic Acid Chemistry enthusiasts
Congratulations to all poster prize winners!! And many Thanks to all participants, speakers, chairs, poster presenters, and helping hands!
Congratulations to all poster prize winners at the DNG meeting, including our @FlorianWeissen1 🥇. Big thanks to @HoebartnerLab for organizing this fantastic conference. 🙏
DFG's delegation & VP Karin Jacobs visited New Dehli to honor 50 years of Indo-German Science & Technology Cooperation with @bmbf_Bund & @IndiaDST. More reasons to celebrate: Our partnership with DST for 20 years & the start of the 1st DST-DFG indo-German #IRTG.
📣Become part of the International Research Training Group 2991. 🇮🇳🌟🇩🇪 Join one of 12 PIs @Uni_WUE for a PhD in the field of "Photoluminescence in Supramolecular Matrices". ℹ️uni-wuerzburg.de/irtg2991
The power of chemical synthesis for studying #RNAmodifications by atomic mutagenesis. Check our nitrogen-deficient m6A analogues, and what they tell us about m6A recognition by proteins. just published in @J_A_C_S
Atomic Mutagenesis of N6-Methyladenosine Reveals Distinct Recognition Modes by Human m6A Reader and Eraser Proteins | Journal of the American Chemical Society @HoebartnerLab @Uni_WUE #Mutagenesis #Methyladenosine #m6A #Reader #Eraser #Proteins pubs.acs.org/doi/10.1021/ja…
Atomic Mutagenesis of N6-Methyladenosine Reveals Distinct Recognition Modes by Human m6A Reader and Eraser Proteins | Journal of the American Chemical Society @HoebartnerLab @Uni_WUE #Mutagenesis #Methyladenosine #m6A #Reader #Eraser #Proteins pubs.acs.org/doi/10.1021/ja…
A good start into the new year, check out our new paper in @JOC_OL on BN-Phenanthrene- and BN-Pyrene-Based Fluorescent Uridine Analogues in cooperation with the @HoebartnerLab Group! Congratulations to @Michi_Chemie for your first publication! doi.org/10.1021/acs.or…
Gegen den Rechtsdrift: Wir brauchen eine offene Gesellschaft! Mein Beitrag heute @faznet faz.net/1.9452332?prem…
Thrilled to receive the Hansen Family Award and deeply grateful for the honor. Thank you to @BayerFoundation and to everyone who made this possible!
Here are the winners of this year’s #Science Awards: Congrats to @HoebartnerLab for being awarded with the Hansen Family Award and @gaofir, Dr. Erin Stache, @skinniderlab and Dr. Vivi Maketa for winning the Early Excellence in Science Award. bayer-foundation.com/and-bayer-foun…
Read a News &Views about #SAMURI by @RentmeisterLab in @NatureChemistry nature.com/articles/s4155… Thank you for highlighting !
Pleased to share our latest work, which was just published in @ChemicalScience. Benzylation of biomolecules in a MAT/MTase cascade. Applied to mRNA, you affect translation and immunogenicity. Congratulations to all authors 🎉 @EnzymeNicoCorn, @RMineikaite pubs.rsc.org/en/content/art…
#SAMURI is a new #ribozyme for RNA-catalyzed labeling of RNA. It uses a new cell-permeable SAM analogue and generates a novel propargylated nucleotide in RNA. Check out the full story doi.org/10.1038/s41557… rclcu.be/dlcxN
New #ribozyme #SAMURI uses a new synthetic cofactor to make #RNA in living cells accessible for #ClickChemistry: Congrats on this publication @NatureChemistry to @HoebartnerLab @JoergLab @Helmholtz_HIRI! ➡️ go.uniwue.de/ribozyme-samuri
Still time to apply
Are you looking for a #graduate program that will launch your career in the fast-growing field of #RNA-based #medicine? 🧬🎓 @RNAmedBavaria is offering fully-funded #PhD positions (4 years) in Würzburg, Munich, or Regensburg. 👉 Apply by September 17 via rnamed.de!
Ribozyme-Catalyzed Late-Stage Functionalization and Fluorogenic Labeling of RNA (Claudia Hoebartner and co-workers) @Uni_WUE @HoebartnerLab #AngewandteVIP #openaccess thanks to #projektDEAL ow.ly/qXAX50OXTr3
Expanding the scope of RNA-catalyzed reactions @Uni_WUE. This work ow.ly/qXAX50OXTr3 #AngewandteVIPs shows how to install a formyl group in RNA using the methyltransferase ribozyme MTR1. exciting applications for site-specific fluorogenic labeling of RNA and more.
Ribozyme-Catalyzed Late-Stage Functionalization and Fluorogenic Labeling of RNA (Claudia Hoebartner and co-workers) @Uni_WUE @HoebartnerLab #AngewandteVIP #openaccess thanks to #projektDEAL ow.ly/qXAX50OXTr3
🚨Job Alert for Group Leader Position🚨 @JMU #Würzburg is recruiting a junior group leader in #RNAbiology. Start your own lab in a vibrant, international scientific #RNA and #infection environment and apply by May 31st! ➡️ imib-wuerzburg.de/fileadmin/user… @JoergLab @KiskerLab
Check out how to program alkene-alkyne [2+2] photocycloaddition for DNA interstrand crosslinking to block DNA unwinding by helicases, just published in @J_A_C_S Thanks for the great collaboration with @KiskerLab @RVZ_Wuerzburg @Uni_WUE
Programmable DNA Interstrand Crosslinking by Alkene–Alkyne [2 + 2] Photocycloaddition @Uni_WUE @HoebartnerLab @dfg_public #Programmable #DNA #Crosslinking #Alkene #Alkyne #Photocycloaddition pubs.acs.org/doi/10.1021/ja…
📢📢PhD students and postdocs: apply now for the Young Scientist Award Biochemistry 2023 of the GDCh. PIs can recommend their students/postdocs. 👇 en.gdch.de/network-struct… #GDCh_biochem; @StephanHacker2, @Intein, @klanglab, @HoebartnerLab
X-ray model of an NAD+-II #riboswitch by the Micura and Ren labs in @NAR_Open reveals how #ncRNA senses the redox state of a ubiquitous enzyme cofactor. The #aptamer stacks G6 and G42 on the plus-charged nicotinamide ring (cation-pi interaction), and rejects NAD's puckered ring.
Very grateful & deeply honored to receive the prestigious Gottfried Wilhelm #LeibnizPreis 2023 from #DFG. Big big Thank You to my incredible group, all our collaborators and everyone who made this possible. also thanks for all congrats and wishes today
Thank you very much! It is a great honor to receive the 2022 Meyerhof Medal @mpi_mr_hd. I am very grateful to my team for their outstanding work!
100 yrs after Otto Meyerhof was awarded the Nobel Prize in Physiology/Medicine. We were honoured to award Dr. Claudia Höbartner last week with the 2022 Meyerhof Medal.🎖️ Congratulations @HoebartnerLab !