HeilemannLab (ππ» heilemannlab.bsky.social)
@HeilemannLab
Single-molecule biophysics lab at Goethe University Frankfurt. Super-resolution microscopy. We moved ππ» https://bsky.app/profile/heilemannlab.bsky.social
Two great days of science at the #SMLMS2022, culminating with a conference dinner on the boat on the Seine. So many great conversations π. Happy to present our choreography to show our appreciation to this event (watch the light pattern!).

bsky.app/profile/heilemβ¦ πhoping to re-connect to many of you
β¦ and perfect timing. Work by @HuaipengXing with @FrydmanLab out @Nature. PDCD5 binds virtually all open #TRiC, while closed TRiC forms clusters inside of cells. Congrats to all authors. rdcu.be/d3dmN
Open postdoctoral position in my group! jobs-sf.ukmuenster.de/job/UKM-Postdo⦠We search for a very talented student in the field of super resolution microscopy! @UK_Muenster @uni_muenster #academia #newPI
Long-term single-protein tracking up to 30 min allowed monitoring the dynamics of EGFR activation in living cells (and more)ππ»Great work by a fantastic team and great collaboration with @JulianKompa Kai Johnsson @mpi_mr_hd π @sfb1507 @goetheuni
Long-Term Single-Molecule Tracking in Living Cells using Weak-Affinity Protein Labeling (Mike Heilemann and co-workers) @HeilemannLab #openaccess onlinelibrary.wiley.com/doi/10.1002/anβ¦
Gen-AI producing fancy data augmentation for Super-resolution microscopy! Great work @AlonSaguy and team! @HenriquesLab @HeilemannLab
If robots could dream of microtubules, how would they look like? An amazing story by Alon Saguy, @ShechtmanLab and colleagues. Proud we could contribute to it onlinelibrary.wiley.com/doi/10.1002/smβ¦
Our Gentle Rhodamines is finally published @ACSCentSci. See the healthy cytoskeleton free from photodamage even after 800 frames! π¦Ύπͺ pubs.acs.org/doi/10.1021/acβ¦ Great collaboration with Julian Kompa, the Johnsson group, and Spirochrome! @JulianKompa @spirochrome @TianyanL
3 weeks to go... send us your single-molecule bacterial stories for our Cotswolds get-together!
Interested in a fully automatic analysis pipeline to quantify and classify your 2D and 3D Single-Molecule Localization Microscopy (SMLM) data in an unbiased way? Have a look at our latest work covering ECLiPSE, developed in the @Melike_Lak lab! doi.org/10.1038/s41592β¦ 1/11
Why reinvent the wheel when you can enhance it? Weβve focused on making SNAP-tag better. @SteffiKuehn developed SNAP-tag2, with an optimized substrate. Faster labeling, brighter fluorescence-this is the upgrade you've been waiting for!
Preprint alertπ¨Did you ever experience issues in labeling kinetics and fluorescence brightness, when working with SNAP-tag in live cells? Our newly developed SNAP-tag2 system might be the solution! πCheck out our latest preprint on #bioRxiv: πbiorxiv.org/content/10.110β¦ (1/4)
We see each other next year in Bonn, Germany in #SMLMS2025 hosted by @UEndesfelder and @HeilemannLab
I am chiming in: fantastic meeting, congratulations and thank you to @HenriquesLab and @MicrobeMatos & entire team! #SMLMS2024 @SMLM_Symposium Looking forward to #SMLMS2025 and working with @UEndesfelder to make it happen. The bar is high π . Hope to see you all again in Bonn!
Well done, Claudia! π
Claudia Catapano from @HeilemannLab presented her PhD work using Single Particle Tracking #SPT to study ligand-dependent membrane receptor activation π§« #SMLMS2024 @SMLM_Symposium
our next talk features @JumanaAHA and her impressive work on chromosomal homolog interactions π§¬π¬ Jumana is also a new PI hiring, start applying now π #SMLMS2024 @SMLM_Symposium
ππ» great job opportunity for a PhD/Postdoc in a new lab headed by a great young PI ππ» @miCHRIScopy. Exciting research in a great research environment!
Claudia Catapano from @HeilemannLab presented her PhD work using Single Particle Tracking #SPT to study ligand-dependent membrane receptor activation π§« #SMLMS2024 @SMLM_Symposium
SMLM community! #SMLMS2024 check out our new preprint, a searchable repository (nano-org) for biological SMLM data allowing comparisons of nanoscale organisation π¨π»βπ» ππ’. Registrations data for uploads encouraged π. Links below. nano-org.bham.ac.uk biorxiv.org/content/10.110β¦