Harry Orrin

Excited for the first day of the UK DNA Replication Meeting 2024! First up: all things initiation. @BiochemSoc #BiochemEvent

🚨📣 Excited to share our latest work investigating how the replisome responds to topoisomerase-DNA crosslinks 🧬🔬 cell.com/molecular-cell… Fantastic work from @rosewesthorpe and @JohannJRoske 🍄🍄🍄🍄

Online Now: Mechanisms controlling replication fork stalling and collapse at topoisomerase 1 cleavage complexes dlvr.it/TCprbz

We are excited to share new mechanistic insights into DNA replication fidelity! How does human DNA Polymerase Epsilon recognise and proofread errors made during synthesis? 🧬 Read @NatureSMB nature.com/articles/s4159…

🔬📚 Very excited to share our new paper titled "How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication"! 🧬 A #tweetorial below ⬇️ @MolecularCell @Yeeles_lab #ScienceTwitter #cryoEM #replication #DNA #polymerase #primase #MolecularBiology #replisome

.@Cambridge_Uni's Philip Zegerman will decipher the modes of action of nucleoside analogues, with the aim of discovering new effective drug combinations and tumour suppressors for improved cancer targeting [2/10]

My PhD work is published today in Molecular Cell!! 🥳 A short thread 🧵 (1/12) cell.com/molecular-cell… #phosphatase #DNAreplication #cellcycle #PP2A #originfiring

We are pleased to announce that the 2023 GSN meeting will take place at West Road Concert Hall in Cambridge on Fri 13th Jan 2023. Looking forward to seeing everyone in person again for the first time in a couple of years. Registration open now! eventbrite.co.uk/e/gsn-2023-mee…

1/ Concerning report. Smoking is biggest cause of cancer & premature death.🚬is an addiction not a choice & Govt has a duty to help. They must publish a full Tobacco Control Plan with action to reach #SmokefreeUK, which would reduce impact on NHS & economy.theguardian.com/society/2022/o…

A cracking and very helpful diagram of the breakdown of running UK appliances to help you through the energy crisis:

Liz Truss has cancelled her BBC One interview with Nick Robinson which was due to air this Tuesday evening (30th August) at 7pm. Ms Truss’ team say she can no longer spare the time to appear on “Our Next Prime Minister”. (1/2)

(1/4) Calling all local artists!🎨📢 We are currently seeking artist submissions to our Addenbrooke’s Affordable Art Sale: 14th Oct-4th Dec 2022. This exhibition is an opportunity for artists to display and sell their work and we’d love to hear from you.

❗️Another week, another PhD student has come to my office in tears as they can’t afford to live in London on £18k. And this is before the price cap increase. @UKRI_News this time - can I ask what you are doing to support the next-generation so there is a next-generation?! Pls RT

Very excited to share our latest research on immunological features of #LongCovid. Our 2+ year collaboration with @PutrinoLab with many other fantastic colleagues and patients - Mount Sinai Yale Long COVID (MY-LC) study by @sneakyvirus1 et al. 🧵(1/) medrxiv.org/content/10.110…

NEW: An Oxford study estimating the environmental impact of 57,000 food products in the UK and Ireland has been published. Researchers found that plant-based foods have the lowest environmental impacts and more nutritious foods are often more sustainable. 🧵⬇️

Upstairs writer’s room at Shakespeare & Company — windows open to the Paris night

“This grant proposal describes breeding experiments in peas. This reviewer remains unconvinced about the translational benefits. Applicant should switch to a more economically important crop like wheat. Applicant’s productivity also an issue, no paper published in last 8 years”.

Did you know that a UK PhD stipend is so little that it puts recipients below the absolute poverty line? UK PhD stipend (outside London): £16,062 Absolute poverty line (60% of 2011 median income): £16,883 No one does research for the money but surely we can do better than this?

Really looking forward to this- if you're around, would be great to see you. 🎟️Sign up here 👉 forms.gle/XUBjyew9wEZzrr… 📅22nd July 2022 📍The Cambridge Union