Huocong Huang
@HHuanglab
Huang Lab, UT Southwestern Medical Center. Studying fibroblast in cancer, wound and aging.
Happy to share our work on pan-cancer analysis of apCAF at an unprecedented resolution Single-cell resolution spatial analysis of antigen-presenting cancer-associated fibroblast niches biorxiv.org/content/10.110…
Happy to share our new #NIHfunded study! Led by Kath Oñate + crew of #WomenInSTEM 💪🏾💪🏻💪, we ID potential of normal mesenchyme to restrain #inflammation, epithelial identity, & #pancreaticcancer via KITL, a cue lost in transition to a CAF state. @CD_AACR aacrjournals.org/cancerdiscover…
AXL-TBK1 driven AKT3 activation promotes metastasis | Science Signaling science.org/doi/10.1126/sc… Long saga, but it is out. @enarner and a host of others pushed this through. Special thanks to Jim Lorens and his lab @UiB
Thank you Anirban ☺️
A really comprehensive fibroblast review in primary and metastatic cancers! In @trendscancer from @BiffiGiulia @marta_zaccaria_ @Pris_Cheng Wonderful job! Illustrations below highlighting (A) Cues that contribute to fibroblast heterogeneity in cancer (B) Fibroblast Cancer cell…
Scientists have identified how the redox sensor #KEAP1 promotes antiviral T cell activation and stem-like T cell responses during chronic viral infections in mice. @utswimmuno @lab_yao Read more in Science #Immunology: bit.ly/4i6n0K2