Gaspard.kerner
@GaspardKerner
🇦🇷🇫🇷Post-doc in Alkes Price’s group, HSPH, Boston
Now published in @CellGenomics! 🧵 (1/8) cell.com/cell-genomics/… #paleogenomics #ancientDNA #selection #infection #immunity #medical #healthcare #autoimmunity #inflammation #pleiotropy #research

Excited to share our latest preprint, as part of ENCODE4, on a consensus variant-to-function (cV2F) score for functionally prioritizing variants for complex disease - led by Tabassum Fabiha and co-mentored with Alkes Price. biorxiv.org/content/10.110…
A new @Nature paper from Drs. Andrés Arias (@AriasAAS) and Anna-Lena Neehus (@ALNeehu) explores how two cousins with a #TNF deficiency experienced recurrent bouts of #tuberculosis, but are unaffected by other pathogens. 📎 go.nature.com/3ToPSlU 🗨️ bit.ly/4gi9p1g
Happy to share our CNN on aDNA genotypes to assess natural selection strength and timing ! To access the article published in Molecular Ecology Resources: doi.org/10.1111/1755-0… @Etienne_Patin @QuintanaMurci and @GaspardKerner #aDNA #paleogenomics @institutpasteur @CNRS
Absolutely stoked that my PhD work, supervised by @MonsieurRoti and @QuintanaMurci, is out @Nature! A story of adaptation to viral pressure across human populations and immune cell types. 🧵 (1/18) (TL;DR below). tinyurl.com/6de4urnr
Happy to share our @naturepaper on how past pathogen exposure, human genetics and evolutionary factors (eg Neanderthal introgression) affect population differences in immune responses to SARS-CoV-2. Led by @aquino_yann @MonsieurRoti and many others! (1/5) nature.com/articles/s4158…
Quand la #paléogénomique renseigne sur l'évolution du système immunitaire humain façonné par les microorganismes pathogènes au cours des derniers 10 000 ans, grâce à une mesure de la sélection naturelle en temps réel. bit.ly/44N9942 #oa @institutpasteur @cdf1530 @CNRS
Exciting new research by @Glaval1Laval at @QuintanaMurci! CNN on aDNA genotypes to delve into allele frequency trajectories, assessing selection strength and timing. Advancing ABC-based methods, with scripts and tutorials coming soon.Stay tuned! rb.gy/64y1p #aDNA🤠☠️
In case you missed this very interesting #SMBE2023 symposium on host-pathogen coevolution and #aDNA, the recorded video stream is now available here: vimeo.com/848507975/e5b4…
Today is the day! Come to see how humans and pathogens have co-evolved together 🧬 Great speakers will drive us into this journey! @H5P53 @pie_federica @MiriamJBravo1 @OfficialSMBE #SMBE2023
📣We're hiring! Please RT and share. #postdoc position in statistical genetics at @HarvardDBMI. Salary above normal range.
The "Host-pathogen co-evolutionary dynamics through the lens of paleogenomics" symposiums at #SMBE2023 is starting today with the poster session. Very interesting posters and great presenters are waiting for you! @MiriamJBravo1 @pie_federica @Linda_Ongaro @OfficialSMBE
Filled with immense pride and gratitude for being a part of the 2nd International Symposium on Inborn Errors of Immunity expertly organized by @casanova_lab and team. Outstanding scientific research conducted by exceptional scientists in a delightful setting #FaroeIslands

Happy to share our latest report on a new clinical manifestation in p40phox deficiency! There is still so much to learn! Great work together with @casanova_lab @BustamanteJaci1 @LevyRomain and others who are not yet on twitter. pubmed.ncbi.nlm.nih.gov/37198372/
Our genomic research of Taiwanese Austronesians is now out in @PNASNexus! We study and leverage the diversity in Taiwan to understand better the genetic profiles of early (pre-) Austronesians, who moved into and out of Taiwan. doi.org/10.1093/pnasne… 🧵: