Frontiers in Science

Hospital pharmacists could soon craft advanced personalized medicines for rare disease patients directly at the bedside. Read more in the article in Frontiers in Science, by authors Mariona Estape Senti, Alexandre Ceccaldi, Raymond Schiffelers, and more ⬇️

The development of mRNA technology is reshaping rare disease treatment. NANOSPRESSO leverages decades of mRNA innovation to enable bedside creation of personalized nucleic acid treatments for rare diseases, even in low-income regions. Read the article in Frontiers in Science ⬇️

🎥 Missed the recent #FrontiersForum webinar on NANOSPRESSO—a new platform that could allow hospitals to create personalized, nucleic acid therapies for rare disease patients right at their bedside? You can watch the recording now ➡️ youtube.com/watch?v=jnaip7…

Many rare diseases stem from errors in our genes, causing cells to make too many, too few, or dysfunctional proteins. Read the explainer on how nucleic acid therapeutics could help treat these conditions ⬇️

Medicines for rare diseases are often out of reach due to high costs and access barriers. NANOSPRESSO could enable local, in-hospital production and boost patient access to treatment. Read the explainer of a new article in Frontiers in Science to find out more ⬇️

Rare diseases affect 300 million people, but treatment options remain limited. Inspired by the convenience of coffee pods, the new NANOSPRESSO project enables hospital pharmacists to ‘brew’ personalized nanomedicines on site. Find out more on the Frontiers in Science hub ⬇️

At today's #FrontiersForum Deep Dive, Prof Raymond Schiffelers led an expert panel discussion on NANOSPRESSO—an inexpensive, portable manufacturing device that could bring equitable, affordable precision medicine for rare diseases within reach. Video coming soon!

Approaches such as NANOSPRESSO could improve the lives of persons living with a rare disease by making advanced, targeted treatments more effective, inclusive, and patient-centered. - Alexandra Heumber Perry and Debra Bellon of Rare Diseases International, in @FrontPolicyLabs ⬇️

A new platform that produces nucleic acid nanomedicines to order for individual patient needs—tailored like espresso capsules—could empower hospitals and revolutionize how we make novel therapies. Hear more at this #FrontiersForum webinar—register now! ➡️ fro.ntiers.in/iH7n

NANOSPRESSO isn’t just technically feasible—it’s also positioned to navigate regulatory hurdles, using exemptions allowing hospital pharmacies to compound personalized therapies for individual patients. Read the viewpoint by Olga Khorkova & Claes Wahlestedt of @univmiami ⬇️

Could an inexpensive, portable manufacturing device bring equitable, affordable precision medicine for rare diseases within reach? Hear from our Frontiers in Science article authors on the new NANOSPRESSO platform at this #FrontiersForum webinar. Register ⬇️

Successful use of personalized RNA therapies in hospitals depends on sterility, good manufacturing practice, and clear regulations, according to Prof Horacio Cabral of @UTokyo_News_en. Read his viewpoint on a recent article on the NANOSPRESSO platform in Frontiers in Science ⬇️

How can precision medicine be more patient-centered and equitable? By shifting from traditional drug pipelines to collaborative care ecosystems, using models like NANOSPRESSO, say Dr Daniel Petersheim and Prof Christoph Klein of @LMU_Muenchen. Read their editorial ⬇️

The NANOSPRESSO project aims to treat rare diseases by enabling hospital pharmacists to assemble cartridges of bespoke medicine in-house, boosting treatment access. Explore the hub of expert articles from Mariona Estape Senti, Raymond Schiffelers, @schoenbuchhase, & more ⬇️

Millions of patients with rare diseases lack treatments due to high drug costs and small markets. NANOSPRESSO offers a solution: onsite, affordable nucleic acid therapeutic production in hospitals. Register for this #FrontiersForum webinar to hear more ➡️ fro.ntiers.in/iH7n

Prototype Device May Enable On-Site Gene Therapy A new device to locally manufacture personalized medicines could boost access to #genetherapy at a fraction of the cost @UMCU_Intl #rarediseases #biomanufacturing hubs.li/Q03tWt360

How gene therapy device could create personalised medicines for rare diseases 🔗Read more trib.al/DqFNJ6U

Explore a new point-of-care model for affordable, on-demand personalized nucleic acid nanomedicines that could revolutionize the treatment of rare diseases. Register for this #FrontiersForum webinar to hear from our Frontiers in Science article authors ➡️ fro.ntiers.in/iH7n

Our approach is unique. Each lead article includes extra content for all walks of life—making science accessible to all. Hubs include: 🧠 Expert views 📋 Policy angles 🎥 Explainer, infographic & video 🧒🏽 Kids’ version 🗞️ Press materials Explore: frontiersin.org/journals/scien…

A woman arrives in ER with fever. Hours later, she’s in septic shock—losing limbs, fingers, and kidney function. Protocols as they currently are may not have saved her. A viewpoint article explores this fictional case and how predictive medicine could transform sepsis care ⬇️