Simon Stern
@DrSStern
Consultant Haematologist. Interested in haemato-oncology in general and multiple myeloma in particular.
🚨 NEWS 🚨 @EU_Commission grants approval to subcutaneous daratumumab monotherapy for the treatment of high-risk smoldering #MultipleMyeloma; based on data from the phase III AQUILA study. This approval represents the first authorized treatment in this indication. Read more:…
Just out! Current Risk stratification of all Plasma Cell Disorders. MGUS, SMM, Myeloma, Amyloidosis. We paid Open Access fees so you can download and read freely! Lots of Tables. Bookmark. @ZanwarSaurabh @myelomaMD @LeukemiaJnl Link: nature.com/articles/s4137…
Thanks to @Myeloma_Doc for highlighting a further publication from the iTIMM study, led by @ProfMessiou @royalmarsdenNHS. MRD detected by whole body MRI clearly predictive of PFS post ASCT. @MyMKaiser
#Myeloma Paper of the Day: Residual disease assessed w/ whole body MRI per MY-RADS protocol linked to shorter PFS (median 24 vs. 42 months) and OS (median 47 months vs. NE) in newly diagnosed or at first relapse patients undergoing first ASCT: pubmed.ncbi.nlm.nih.gov/40675973/. #mmsm
Phillies debut the “Coldplay Kiss Cam”. Wait for it…
Two specific situations where belantamab can have a major impact are 1) Relapsed high tumor burden myeloma that is refractory to other myeloma drugs and where CART or bispeicifics will be too risky. Here even a few doses of belantamab to control myeloma can open up other…
Persuasive data. Lenalidomide often added for cycles 2 & 3 onwards after starting with DVD or D-CVD. Can't be done in the UK (yet). #mmsm Early daratumumab therapy improves renal outcomes in newly diagnosed patients with myeloma admitted with AKI ashpublications.org/bloodadvances/…
Do we need maintenance therapy for everyone in quadruplet era? particularly relevant for older adults with CEPHEUS and IMROZ results. lucky me that I got to write this with @End_myeloma 😃 onlinelibrary.wiley.com/doi/full/10.10… @McMasterU
Nelson Mandela's World Cup moment was 30 years ago on Tuesday. Inequality hasn't shifted in South Africa but the magic of that day endures. My column for @ObserverUK observer.co.uk/news/sport/art…
Somewhat strange to hear @bbcnickrobinson haranguing an NHS Consultant for being on “over £100,000” and claiming to channel the feelings of ordinary people. His salary in 2024 was between £345,000 - £349,000. For presenting radio programs. Which never saved anyone’s life?
Breaking: Big news for smoldering myeloma. The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended the approval of a new indication for DARZALEX®(daratumumab) subcutaneous (SC) formulation as monotherapy for the treatment…
1/2 Many people living with myeloma experience symptoms for months or even years before receiving a diagnosis. By sharing this post, you can help raise awareness and make sure more people recognise the warning signs sooner ⚠️ #MyelomaAwarenessWeek #MyelomaWarningSigns
CONGRESS | #EHA2025 | PRESENTATION Shaji Kumar @myelomaMD @MayoClinic presents results from the phase II RedirecTT-1 trial of talquetamab + teclistamab in patients with RRMM with EMD. Tal + Tec led to an ORR of 78.9% and a ≥CR rate of 54.4%; efficacy exceeded standard therapies,…
This is the worst cover of Penny Lane, I have ever heard.
Really important session by Come Bommier discussing burnout amongst haematologists #EHA2025 @EHA_Hematology
Theatre in the round for an excellent debate on R-CHOP v R-Pola-CHP for diffuse large B-cell lymphoma at #EHA2025
Very innovative for #EHA2025 to run a session on Space Haematology. @AryaRoopen very enlightening on the risks and potential treatment of VTE on a space station.
