Prof Derek Connolly

Rivaroxaban demonstrated similar efficacy to warfarin in treating post-MI LVT, with >95% resolution in both groups.

While HbA1c levels <7% are recommended in DiabetesCare,¹ achieving <6.5% (48 mmol/mol) within the first year of T2D diagnosis minimize the risk of micro- and macrovascular complications.²

Today, we take the next step in Verve’s journey: the acquisition by @EliLillyandCo is now complete. From the founding of Verve in 2018 to this milestone in 2025, we have worked with urgency and conviction to advance a bold idea — that a single-course gene editing medicine could…

Our paper by @DrJayneMorgan @HelloHeartApp is now out @AJPCardio BP ⤵️ by gender & menopause status among hypertensive participants using a novel mobile health cardiovascular risk self-management program #AI #MobileApp #MedTech #healthtech #CVPrev 📎 shorturl.at/V4tgP

Physical activity in >50,000 people with Type 2 diabetes: weekend warriors were associated with reduced all-cause mortality and cardiovascular mortality c.f. sedentary individuals @AnnalsofIM acpjournals.org/doi/10.7326/AN…

🦋 GLP-1RAs not associated with increased thyroid tumour risk In >4M people with T2 diabetes across U.S. cohorts: 📉 Thyroid tumour incidence was low (0.88–1.03 per 1,000 PY) ⚖️ No increased risk vs SGLT2i, DPP-4i, or SUs across multiple comparisons diabetesjournals.org/care/article/d…

In the #POINT trial, prior statin use was linked to a📉risk of early #stroke recurrence (<7 days). Starting statins after the event did not. ➡️Early prevention starts before the stroke! tinyurl.com/2m5abjep @JacopoImberti @escardio @Fra_Vitali90 @L_Bergamaschi

In 2023 we produced a fabulous series of 8 webinars on lipid management. Here are the links for all webinars (a thread - 🧵1/5). (1) Interpretation of Lipid Profiles & Other Lipid Optimisation tests youtu.be/5zbIRZfuLg4?fe… (2) Managing statin intolerance youtu.be/NALw5t31J-E?fe…

Fantastic photo of @AstonMedicine graduates from last week Honoured to be there Can you spot me?

Delighted w our Cunsensus Document @escardio on preventing heart failure in cardiac-oncology published at #EJHF @ESC_Journals onlinelibrary.wiley.com/doi/10.1002/ej… Potential importance of SGLTi noted academic.oup.com/eurjpc/advance… W @m_piepoli @MarcoMetra @FarmakisD @DrMarthaGulati @mmamas1973

Can pharmacy do more to prevent cardiovascular disease in minority ethnic communities? I’m exploring how, through my PhD research at Aston University. Your insights could help inform approaches to CVD prevention in minority ethnic groups. For details, check the poster below:

🩺 SGLT2i associated with ⬇️ RAASi discontinuation & hyperkalaemia In >20,000 older adults (95% with diabetes, 32% with CKD, 17% with HF): jamanetwork.com/journals/jamai… #CKD #HeartFailure #Diabetes #RAASi #MedTwitter

Inclisiran isn’t just an add-on. As monotherapy, it slashes LDL-C and could reshape lipid-lowering for statin-intolerant patients. 💡🧬 jacc.org/doi/10.1016/j.… #JACC #ASCVD #cvLipids #cvPrev

In this UKBiobank study, lipid risk of CAD is most accurately reflected by the total apolipoprotein B & is largely unaffected by major particle type (VLDL, IDL/LDL), count, or size. However, elevated Lp(a) count poses a significant additive risk Apo B measurement is the future

Tirzepatide improves metabolic hypogonadism better than transdermal testosterone according to this study presented at #ENDO2025. Always happy to give my comments for MedCentral. medcentral.com/endocrinology/…

How stable is your Lp(a)? In >11,000 patients, borderline Lp(a) levels (30–50 mg/dL) often changed over time, especially in women, those with ASCVD, on statins, or with high LDL-C. 📊 Repeated testing may be key for accurate risk assessment. 🔗 Read more: tinyurl.com/4ctxp6fs

Best kind of message is when you convince an interventional cardiologist to come to #ASPC2025 #CVPrev @DrMichaelShapir @AkhilGulati

👉Managing Dyslipidemia in 2025: The Era of Precision Lipidology ☝️As we move through 2025, dyslipidemia management has clearly evolved beyond the traditional statin + ezetimibe approach. ☝️We now have an expanding armamentarium of targeted therapies addressing…

Honoured to be at the @AstonMedicine graduation ceremony today with @DrBruceKeogh to see so many young doctors & HCPs receive their degree. Wonderful to see⭐️ @DavidNichols0n, the best chief executive of @NHSEngland ever, receive an honorary doctorate. @SWBHnhs @AstonPress

#Lipoprotein(a) and Cardiovascular Risk in #Asian Populations: pubmed.ncbi.nlm.nih.gov/40492182/