David Whalley
@DavidWorley94
Postdoc at AstraZeneca UK in Synthetic Methodology Previous: @ChemCambridge @greaneygroup @astar_research @ChemistryUoN
Proud to share my first paper as corresponding author from my postdoc at @ASTRAZENECAUK. We found a way to make oxa-BCH rings from simple allyl alcohols in a fast cascade reaction, with control of substitution at every position. @ChemicalScience surl.li/xigpdh

Tom and his amides are back at it again! Check out this concept! …mistry-europe.onlinelibrary.wiley.com/doi/abs/10.100…
3.5-year PhD studentship (Sept 2025 start) available focusing on "Photocyclisations as Enabling Atom-Economical Transformations! Collaborative project led by @BathChem with 1 year at @MonashUni. bit.ly/4iAJLWA
Intermolecular Asymmetric Arylative Dearomatization of 1-Naphthols | Journal of the American Chemical Society @Cambridge_Uni @ChemCambridge @TotalSyntheses #Arylative #Dearomatization #Naphthols pubs.acs.org/doi/10.1021/ja…
We have just published a vacancy for a Postdoctoral Fellow – Biocatalysis in Drug Discovery at Astrazeneca in Gothenburg, SE: organic-chemistry.org/jobs/offers/?q… - please check and share!
Was great to see the work come to life! Congrats to the Phipps team on a great paper. Another testament to the power of cinchona alkaloids 🧪 science.org/doi/10.1126/sc…
Congrats Nick and the team!
Enantioselective Nitrene Transfer to Hydrocinnamyl & Allylic Alcohols Enabled by Exploration of Structure of Ion-Paired Rh Catalysts | JACS @ChemCambridge @Cambridge_Uni @TotalSyntheses #Nitrene #Transfer #IonPaired #Rh #Catalysis pubs.acs.org/doi/10.1021/ja…
Just accepted in @angew_chem, we report an amide linked, photocatalytic STR biaryl synthesis that can be telescoped to achieve a challenging C-N arylation of anilines. Check out @Tom__Sephton's work here! onlinelibrary.wiley.com/doi/epdf/10.10…
Smiles rearrangements at it again 💪🏻
Didn’t have a chance to do C-N coupling while I was in the @HartwigGroup, so decided to give it a try and see what it was like. Published in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Thomas Wharton: release the amides! Check out this lovely piece of work from the @SpringGroupChem group on the controlled release of amide containing molecules onlinelibrary.wiley.com/doi/10.1002/an…
Our lab website is now live + we're hiring for Fall 2024! Check out lam-lab.ca to see what we'll get up to at @chemistryatuvic, and reach out if you'd like to be part of the team! #chemtwitter #chemistryPhD #ochem
Top work from some top labmates!
Well done to Kieran, Amit & Ben for all of their hard work on an amide directed C-H amination with ion-paired Rh catalysis ✨ onlinelibrary.wiley.com/doi/10.1002/an…
Out now in Chemrxiv, we're excited to report a simple protocol for the direct synthesis of benzenes from pyridines, through an N to C switch. Congrats to Aife for her work on this project! chemrxiv.org/engage/chemrxi…
Congratulations Tom Wharton on winning the RSC Medicinal Chemistry Poster Prize at the @RSC_CBBG forum last week👏 @SpringGroupChem
Well done to Kieran, Amit & Ben for all of their hard work on an amide directed C-H amination with ion-paired Rh catalysis ✨ onlinelibrary.wiley.com/doi/10.1002/an…
Thrilled to say that from Jan 2024 I will be taking a position as a Postdoctoral Fellow at @ASTRAZENECAUK at their Cambridge Discovery Centre. Excited for this next chapter
Just accepted in @angew_chem, we report a tunable system for C4/C5 Pyridine C-H arylation using Zincke imine intermediates. Congrats to Haiwen for all his work on this solo effort! onlinelibrary.wiley.com/doi/10.1002/an…
sSPhos: A General Ligand for Enantioselective Arylative Phenol Dearomatization: Electrostatically-Directed Palladium Catalysis | Journal of the American Chemical Society @ChemCambridge @Cambridge_Uni @TotalSyntheses #Enantioselective #Dearomatization #Pd pubs.acs.org/doi/10.1021/ja…
📣 Don't miss Alexander Fanourakis & Robert J. Phipps' new @ChemicalScience Review 📣 Catalytic, asymmetric carbon–nitrogen bond formation using metal nitrenoids: from metal–ligand complexes via metalloporphyrins to enzymes 🔗 doi.org/10.1039/D3SC04…
Expectation of postdocs to move around is just unrealistic and you need to be extremely privileged to do it. It's a huge (unfair) reason why so many talented researchers are lost along the academic pipeline. science.org/content/articl…