Daniel Fehrenbach
@DJFehrenbach
Postdoctoral Fellow at Indiana University School of Medicine Studying the role of immune activation in Takotsubo Cardiomyopathy and hypertension
I'm excited to announce that my K99/R00 was funded studying the role of ROCK2 in Immune Mechanisms of Takotsubo Cardiomyopthy! Thank you to everyone who has helped along the way!
Great work by @EmilyCBurns and the Mattsonites at @AUG_University @DasingerJh @AbaisBattad @SDWalton44 on a great set of studies published now in JASN @asnpublications! #hypertension #immune #kidney #CD14 #oxidativestress
Your data is lying to you. Here’s how technical artifacts distort biology—and how to see the truth. 👇 1/ Beautiful t-SNE? Shiny heatmap? Look closer. Technical artifacts can fake whole cell types. Here’s where the ghosts hide.
It’s a wrap. Another @APSPhysiology Summit #2025 with great friends and great science! @Jean_Wassenaar @DJFehrenbach
Continuing the tradition of a morning conference run at the @APSPhysiology #APS2025 in Baltimore with @Jean_Wassenaar!
This is a must-read for everyone involved in metabolomics. Personally I love this article because I no longer have to write a long paragraph when I say 'please don't use pathway analysis' during peer review 🤣 nature.com/articles/s4225…
#ACC25 Sim-pub 🚨📢 FRESH-UP RCT 🥤 504 outpatients w HF Liberal fluid intake vs fluid restriction ≤1.5L/d At 3-months, no difference in health status (KCCQ-OSS) or safety events (mortality/hospitalization/IV LD use), but 📈 thirst distress in fluid restriction arm Led by…
One of the most important trials at @ACCinTouch #ACC25 ! Compared fluid restriction to liberal approach in #HeartFailure. Why? This affects individuals w/HF EVERY DAY! ✨No benefit of Fluid Restriction ✨No HARM for liberal fluid intake ✨Improved QOL in liberal fluid intake
The first report on macrophage-driven inflammation of the cardiac innervating superior cervical ganglion occurring in Takotsubo syndrome. @Karin_A_Ziegler @TU_Muenchen ahajournals.org/doi/full/10.11…
Of >105,000 participants with 30-year follow-up, only 9.3% achieved healthy aging (age 70, w/o any chronic diseases). Their diet was significantly associated with this outcome🧵 @NatureMedicine
Canada healthcare is horrifying “Today on how f*cked is Canadian healthcare: I need an MRI to see if I have a f*cking brain tumor. Go ahead guess when it is? Go ahead, guess. It's in 2026” “My MRI to see if I have a brain tumor is in 2026. It's March 2025 right now” “If you…
Cardiovascular disease is responsible for 30% of deaths in women each year—more than all cancers combined. Yet, heart disease in women is often missed or dismissed. This #WomensDay, inform yourself about heart disease and speak up about your heart health 👇 #ListenToHerHeart
Female cardiomyocytes show higher expression of fatty acid oxidation genes, leading to greater reliance on fat for energy. A key insight into cardiac sex differences! @yoshiko96821 @MayaTalukdar ahajournals.org/doi/full/10.11…
We recently collaborated with @TheChungLab @karlalambaren and Noah Trac to review recent developments on T Cell-Targeting Nanotherapies for Atherosclerosis. Check it out @BioconjChem! @CVimmunology @USCBiomedEng @IUSMDeptMed #nanoparticle #micelle pubs.acs.org/doi/full/10.10…
Excited to share our newest article by co-first authors @Jean_Wassenaar and @smartdunc on the role of IL-33/ST2 in #heart disease.
Targeting the interleukin-33/ST2 pathway has beneficial effects in hypertensive heart disease Read the new #JACCBTS Research Letter by Drs. @Jean_Wassenaar, Madhur & colleagues: jacc.org/doi/10.1016/j.… @CVimmunology @smartdunc
Join us for an excellent webinar for trainees and get the inside scoop on how to excel at poster presentations for Summit 2025! #APS @APSPhysiology
Indiana University Indianapolis has officially received R1 status, cementing our place as one of the nation's premier urban research universities. 🏆 As Indy's only R1 institution, IU Indianapolis is poised to recruit top-tier faculty and talented students - driving innovation,…
Congrats, @Jvanbeusecum. Looks like an amazing resource!
@OPalygin and I are proud to announce the @ResearchMUSC Kidney Translational Research Center! We have established excellent directors, scientists and trainees collecting bio specimens in the realm of renal, vascular, and immunological fields. medicine.musc.edu/departments/do…
Review in the Jan 31st issue of @CircRes by Kohutek et al "The #BoneMarrow Niche in #Cardiometabolic Disease: Mechanisms and Therapeutic Potential" at ahajrnls.org/3PZ6oa2 @AmandaDoran @CVimmunology @DJFehrenbach
Our latest review, spearheaded by @AmandaDoranLab, on the Bone Marrow Niche in Cardiometabolic Disease is out in @CircRes @AHA_Research @IUSMDeptMed @VUMCResearch @HHP_UH @CVimmunology @HeatherCaslin @brettheimlich @JonathanBrownMD @FerrellLabVUMC ahajournals.org/doi/10.1161/CI…