Cuylen Lab

Image-enabled cell sorting (ICS) – a next-generation cell sorting method – is helping EMBL researchers gain new insights into cellular function in health and disease, as well as to explore other innovative applications. embl.org/news/science/t…

Ki-67 shapes the nucleolus by anchoring chromatin via its amphiphilic properties biorxiv.org/content/10.110… #biorxiv_cellbio

For more detail, check out this great thread from one of the first authors @YH_YukiBio explaining the findings:

Ever wondered why nucleoli often have such complex shapes—despite behaving like liquids? If liquids tend to form spheres, why don’t nucleoli? What shapes them? We explore this in our latest preprint @embl. Great work led by Daja Schichler & @YH_YukiBio! biorxiv.org/content/10.110…

Interested in rapid imaging-based screening or sorting of rare cell populations? A new era of cell sorting has begun! Check out our latest review in @TrendCellBio on novel flow cytometers with imaging capabilities. Congrats, @terrabyte21! cell.com/trends/cell-bi…

EMBL Heidelberg researchers found how chromosomes switch from repelling each other to becoming sticky during cell division. They saw that protein Ki-67 turn chromosomes’ surface into a liquid-like glue that helps in the formation of daughter nuclei. 🔛 embl.org/news/science-t…

Extremely happy to see our story out in @MolecularCell! doi.org/10.1016/j.molc… We show how Ki-67 & pre-rRNA phase separate, gluing mitotic #chromosomes together! 🧼🧬🧲 @EMBL @EMBLHeidelberg @UniHeidelberg @ISTAustria @CuylenLab @SaricLab @EllenbergLab

Our latest paper is out today @MolecularCell! Led by a @AHA_Alberto and with important contributions from @SaricLab & @EllenbergLab! We show how chromosomes shift from being repulsive to becoming attractive during mitosis. Read all about it here: cell.com/molecular-cell…

I am extremely happy to share my @biorxivpreprint of my PhD work @EMBL! 🔬👨🏽‍🎓 A liquid-like coat mediates chromosome clustering during mitotic exit biorxiv.org/content/10.110…

Our new preprint describing how Ki-67 switches from a chromosome surfactant to a chromosome glue is online! Fantastic work lead by @AHA_Alberto @embl. Many thanks to our great collaborators from @SaricLab and @EllenbergLab. biorxiv.org/content/10.110…

The EIPOD-LinC postdoctoral programme is open for applications! Are you interested in self-designed interdisciplinary research on projects exploring life in context? Then take a look at our fellowship programme: embl.org/about/info/pos…

Excited to share our collaborative work with the Mahamid, Müller and @EllenbergLab! This has been a fantastic team effort @embl led by Herman Fung, @yukicosmos239 and @VeijoS.

Out today and freely available, a tool many in the image analysis community have been waiting for! PyImageJ: A library for integrating ImageJ and Python @EliceiriK @UWMadisonLOCI @ctrueden @CiminiLab @DrAnneCarpenter nature.com/articles/s4159…

Registration now open for the 2023 Physical Biology Circle Meeting (30/01-01/02) at #mpipks Dresden. All talk slots for #PhD students / #postdocs! Register at pks.mpg.de/cmbp23 before 15/11. (Only members of participating nodes can apply.) #biophysics #mechanics #softmatter

Job Opening!! 🔔⏰🔔 ... In a joint position with the Korbel lab @EMBL we are looking for a skilled computer scientist! Details see add below! Please spread the word and fwd to whoever might be interested! embl.org/jobs/position/…

The #KörberPrize 2022, endowed with one million euros, is awarded to the British cell biologist Anthony Hyman @mpicbg who discovered a completely new state of biological matter. Watch the awards ceremony live: koerber-stiftung.de/en/projects/ko… #cellbiology #scienceprize

One week left to apply for the postdoc position in our lab @EMBL using novel image-enabled cell sorting to study cellular phase separation. Apply here: embl.org/jobs/position/… Come and join us!

Ready for another year full of groundbreaking science? Then check out our events line-up for 2023!🤩 We're excited for brand new conferences and courses as well as tried and true classics such as #EMBLMalaria and #EESImaging 🙌🏻 👩🏾‍💻 Have a look here️: embl.org/about/info/cou…

Are you interested in cellular phase separation and like high-throughput screening and omics technologies? Exciting postdoctoral position available in our lab @EMBL. Closing date Aug 27. For more information see: embl.org/jobs/position/… Please RT!

DeepMind and EMBL-EBI have released the predicted structures of over 200 million proteins covering almost every organism that has had its genome sequenced. These are now openly available to the scientific community via the AlphaFold Database. embl.org/news/technolog…