Cécile Lesueur
@CecileCADS
Very happy to share that our work, with @kaydanych @Prevedel_Lab @claire_deo, developing the first chemigenetic probes and calcium sensors for photoacoustic imaging is out now on biorxiv ! biorxiv.org/content/10.110…
#GPMelt users, it was fantastic meeting so many of you at my #HUPO2024 poster!🎊 As discussed, the revised GPMelt code is now on GitLab. Also, check out the GPMelt website to dive into the model—no advanced maths required! 💻🔍 #Proteomics All links here: linktr.ee/CecileCADS
What a wonderful experience chairing a AI and Bioinformatics Approaches session in the plenary hall at #HUPO2024 yesterday! Big thanks to the organizers for giving me this opportunity, to the speakers for their excellent talks, and to Nuno Bandeira for chairing with me!
Thrilled to see my PhD work published! 🪇 Check out GPMelt, our new framework for uncovering the dark meltome of TPP datasets @savitski_lab @MagnusRattray. Discover how we’re pushing the boundaries of thermal proteome profiling! See the implementation: git.embl.de/grp-savitski/g…
EMBL scientists developed GPMelt, a method to explore proteins with unconventional melting behaviors, previously overlooked in Thermal Proteome Profiling (TPP). By embracing the full complexity of the meltome, GPMelt enables new biological discoveries. journals.plos.org/ploscompbiol/a…
Great to see our work out this week in JACS @kaydanych @Prevedel_Lab @claire_deo Hopefully just the start of a wave of photoacoustic probe development to complement existing neuroimaging tools! pubs.acs.org/doi/10.1021/ja…
Mom turn on the TV!
EMBL scientists applied molecular engineering to build photoacoustic probes to label and visualise neurons deep within brain tissue. A new paper explains how this novel approach improves what scientists can learn about brain functions. embl.org/news/science-t…
🧵1/10 We’re thrilled to share our latest paper, Bicycle, a novel approach for inferring cyclic causal relationships from observational and interventional data! This work addresses a critical gap in understanding complex biological networks.
TPP goes subcellular! We are happy to present the preprint from our lab introducing mito-TPP, an optimized TPP workflow that enables the direct application of TPP on isolated mitochondria for the direct and extensive study of the mitochondrial proteome. biorxiv.org/content/10.110…
Presented our work on photoacousitc calcium probes at @PhotonicsWest with @claire_deo @alexcook8997 and @Prevedel_Lab!
Hierarchical Gaussian process models explore the dark meltome of thermal proteome profiling experiments. biorxiv.org/cgi/content/sh… #biorxiv_bioinfo
I'm delighted to have presented our new GPMelt model @savitski_lab & @MagnusRattray for exploring the dark meltome of Thermal Proteome Profiling #TPP #GP at #EWCSProteomics. Thanks to the organizers for giving me this great opportunity!
