Irene Cantone

Curious to know why men and women are different? It's not only a matter of #hormones. We got into the #Human #Genetics and #Epigenetic of #SexBias in #cancer and #immunity! We discuss evidence that the activity, repair and folding of our genomes gets some of the answer! 1/3

Researchers pinpoint the genes responsible for the final three pea traits studied by Gregor Mendel more than 160 years ago go.nature.com/3EDaPpe

I’d love to hear biologists weigh in on the fundamental question: can you predict the impact of cell perturbations better by studying the natural variation in a population of healthy cells (more data), or by studying cells that have been perturbed genetically or chemically?

I’m incredibly proud to share the results of our lab’s first project, leading to the exciting discovery – Aging promotes reactivation of the Barr body at distal chromosome regions – now published in @NatureAging! 🔗 rdcu.be/ekm0I👇🧵

We are recruiting candidates to apply for the next call! Deadline to preposal is on the 5th of May! Contact me if you are interested in understanding the role of #XChromosome inactivation and #XIST in #sexdifference of #autoimmunity

To the #XchromosomeInactivation field: anyone knows Xist is a long #noncodingRNA Which publication has ruled out that there are protein coding regions within it? And how?

Let's do CRISPRa without virus and plasmids!!! Congratulations to Tobi and all the authors ! It was a really fun project, revealing some exciting results! academic.oup.com/nar/article/53…

Biologists have built one of the most detailed pictures of pregnancy's true toll on the body. Read the full story: go.nature.com/4hUpNES

A perfect example of why targeting funding or policy changes that limit studies on sex differences - especially those incorporating gender as a variable - will set health progress back, particularly for women.

MRI scans show that the brains of infants and toddlers can encode memories, even if we don’t remember them as adults. go.nature.com/4hu9Q86

Women tend to live longer than men and are often more resilient to cognitive decline as they age. Now researchers might have uncovered a source for this resilience: the second X chromosome in female cells go.nature.com/41K8Ubc

A #computational #Postdoc position is available in my lab to dive into #chromatin mediated #epigenetic mechanisms underlying #autoimmune reactions in #MultipleSclerosis! Please RT

If you have completed your PhD less than a year ago and work outside Italy, consider applying for @HFSP fellowship to join our lab! Opening coming soon!

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. go.nature.com/4i9BpEx

📢 FUNDED! I will be recruiting a computational postdoc on our favorite topic #XChromosomeInactivation role on #sexdifferences in #autoimmunity #MultipleSclerosis. If you fancy working on exceptional #singlecell #omics datasets contact me! Predoc fellow with prior experience DM

Happy #WomenInSTEM day!

We're hiring a motivated PhD student! Join @reNEW_Global & @NuclearDn to study how metabolism regulates chromatin & stem cell fate thanks to generous @MSCActions . Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu. @UCPH_health

Attention researchers from all over the world🙃The Call for Letters of Intent for the 2025 HFSP Research Grants is NOW OPEN! 📢 It's time to submit your bold, interdisciplinary research proposals and join forces with scientists worldwide! 👉 Apply now: bit.ly/VU3fU4

Grazie all’università per aver messo in evidenza il nostro recente lavoro sulle Treg e il cancro al seno! unina.it/-/66774917-la-…

📢Excited to introduce NanoCas -our new mini CRISPR system that can reach tissues previously out of reach! By shrinking CRISPR to 1/3 its normal size, we can now edit genes in muscle, heart & brain that were difficult to access before. Summary & link to paper:

1/ Pleased to share our review, published today @NatRevImmunol, highlighting how biomolecular condensates enhance the precision and flexibility of gene regulatory networks that guide fate decisions during normal and pathological immune cell development. nature.com/articles/s4157…