Children’s Research Institute at UT Southwestern
@CRI_UTSW
Interdisciplinary, collaborative researchers seeking #RelentlessDiscovery toward treatments of tomorrow. #regeneration #StemCells #CancerBiology #Metabolism
Excited to receive an NIH K08 Clinical Investigator Award to support my research on #mitochondria #peroxisomes 😀 The $775K will be critical in helping me transition to independence as I begin looking for a place to start my lab 🙏🏻 @A_P_S_A @the_asci @AmerAcadPeds #neotwitter
A cancer breakthrough in North Texas, but how many more will we get? | Opinion dallasnews.com/opinion/editor…
.@CRI_UTSW researchers found tumors can use sugar-coated structures called GAGs to acquire vitamin E from blood, helping them resist cell death. Supported by @CPRITTexas, this discovery could lead to safer, more targeted cancer therapies and reflects the impact of Texas-backed…
Most of us love hotpot so we are back again at Shoo Loong Kan for July's lab lunch and birthday celebration! 🎂 (also socially awkward moment when all their staff sang birthday song to us 🙃) @SihanSean @YoonKimUTSW @QK15622518 @LucasaEast @Burg1ess @yipengxie_utsw
Great workshop led by @TrevorTippetts1 on best practices for poster presentations! The session offered valuable insights on how to design, structure, & deliver an effective poster presentation. It’s always a pleasure to work with @TrevorTippetts1, a postdoc fellow at @CRI_UTSW.
ONLINE NOW: Two new somatic mutation studies in #liver disease from CRI's @Zhu_Lab: 🟠@JHepatology w/ postdoc Qiyu Zeng, Ph.D. journal-of-hepatology.eu/article/S0168-… 🟠@jclinicalinvest w/ grad student Greg Mannino jci.org/articles/view/… 🔖🧵 Hao's thread ⬇️
Intro to 2 new studies from my lab on somatic mutations in liver disease. 1st is about a mutated gene that leads to improved clone fitness and organismal health (CIDEB). The 2nd is about a mutated gene that leads to improved clone fitness but worse overall health (TBX3). 1/8
Inspiring piece in @NatureCancer, "An unexpected career in cancer metabolism," highlights Dr. Ralph DeBerardinis & the pivotal moments that prompted him to pursue a career in cancer metabolism. @CRI_UTSW @HHMINEWS nature.com/articles/s4301…
Research News in @CD_AACR features @JaviGBermudez Lab's #relentlessdiscovery "Lipoprotein Uptake through Glycosaminoglycans Blocks Ferroptosis in Cancer" Read more ➡️ aacrjournals.org/cdnews/news/24…

We’re truly fortunate to have such extraordinary scientists engaging with our summer students. Thank you, Dr. Ralph DeBerardinis, for sharing the groundbreaking science you are leading at @CRI_UTSW. I’m confident that your talk inspired our students and sparked their curiosity.
Very proud to contribute! Emerging evidence links ecDNA with cold TME. But still chicken&egg as we don't know the mechanism yet. Stay tuned for new findings to come.
From the June issue: Spatial-Temporal Diversity of #ecDNA Shapes Urothelial Carcinoma Evolution & Tumor-Immune Microenvironment brnw.ch/21wTJSU By Wei Lv, Yuchen Zeng, Conghui Li, Yuan Liang, Birgitte Regenberg, Yonglun Luo, Chunhua Lin, Peng Han, and colleagues
CRI's latest #relentlessdiscovery featured in @dallasnews today: "Dallas researchers find cancer’s secret weapon to defeat death" read more ➡️ cri.utsw.edu/the-dallas-mor…

📰 NEWS: Scientists have discovered #tumours can tap a nontraditional pathway to acquire lipoproteins which enriches #cancer cells with an antioxidant shield to survive stress, according to new research 🔗Read more here: oncologynewstoday.co.uk/scientists-unc…
Congratulations to Walter Chen, M.D., Ph.D., who is the recipient of a 2025 @BWFUND Career Award for Medical Students. He is the first neonatologist to receive the prestigious award. Read more: bit.ly/3ZCTvIc
Nature research paper: Glycosaminoglycan-driven lipoprotein uptake protects tumours from ferroptosis go.nature.com/4e7u5bM
Researchers at @CRI_UTSW discovered how tumors use glycosaminoglycans to take up antioxidant-rich lipoproteins. This pathway helps cancer cells survive stress and resist cell death, pointing to a potential new target for cancer treatment. bit.ly/3T7W1Cy
Wu lab is 4 years old! Had our anniversary feast today at Dong Bo Sung (again! cause its good!) and 🎂 cake from Ecclesia Bakery @SihanSean @YoonKimUTSW @QK15622518 @LucasaEast @Burg1ess @yipengxie_utsw
Honored to get @BWFUND Career Award for my work on #mitochondria #peroxisomes and be 1st neonatologist awardee! $700K to start my lab = exciting #organelles #metabolism research to help medicine’s smallest patients! #neotwitter bwfund.org/news/bwf-annou…