Bryan Welm

Here it is! Reverse Transcriptase at 42 million times the actual size! Took almost a year to build. It sits on a sculpture that represents the journey of discovery by David Baltimore and Howard Temin. Heading to ⁦@McArdleLab⁩ in few weeks.

I’m hoping to finish the Ras sculpture today! Here it is sitting on a temp stand I use for final polishing and clear coating. GDP and the Ras-targeting drug sotorasib are shown at the bottom. Entirely handmade by TIG welding steel, bronze and copper. No casting. #SciArt

A Precision Oncology-Focused Deep Learning Framework for Personalized Selection of Cancer Therapy 1. The study introduces ScreenDL, a deep learning framework that integrates tumor omic profiles and functional drug screening data to predict personalized cancer therapy responses…

Sneak peek at some of the participating artists: @hhbarrera @loliboldu @patriciabondia @jayeperview @GraphicAnja @ignotofsky @leonoramtzn @molecularmirror @munafomarzia @oreillymk @biyolokum @DrSteffi @RitterLab @foodskop @ksluka0101 @BryanWelm & many more! I am starstruck 🤩

This should be a great event to meet some amazing artist and see some inspirational #SciArt!

Sculpture of the Ras protein (G12C) bound to GDP and the drug Sotorasib (AMG510). The protein is half bronze and half steel with a copper seam between the two metals. Represents how the drug locks the protein in a unique conformation that blocks its function and cancer growth.

WE ARE HIRING! The Department of Molecular Pharmaceutics is currently hiring two tenure-track faculty positions: Assistant Professor - Molecular Pharmaceutics utah.peopleadmin.com/postings/168640 The Sung Wan Kim Endowed Chair in Drug and Gene Delivery utah.peopleadmin.com/postings/168641

In progress sculpture of the molecular surface of G12C mutant KRAS bound to the RAS targeting drug sotorasib. The sculpture is half bronze and half steel with a copper seam between them. I’m currently making bronze/brass versions of the drug and GDP to add to the sculpture.

A close up of the NR2F1 nuclear receptor sculpture for Julio Aguirre-Ghiso @JAguirreGhiso

Sculpture of the androgen receptor protein (AR). The sculpture is of the AR ligand binding domain with the anti-androgen drug enzalutamide, which is used for the treatment of prostate cancer. Made from steel, brass and bronze. #SciArt

Incredibly saddened about the loss of a dear friend and colleague last week. Yoko was a pioneer in breast cancer PDX and enabled our later development of PDX organoids. Please consider donating. Fundraiser by Alana Welm : Dr. Yoko DeRose memorial fund gofund.me/03157aa2

Doing some final welds on a bronze of a T cell killing a migrating cancer cell. Nice colors in the nucleus from the heat. I added steel to the bronze under the T cell so the immune cell will be removable, via magnets. #SciArt

ICYMI, the 10th installment of The Art of Basic Science is out and celebrates several purveyors of science + art including @BryanWelm @biyolokum @RitterLab @molecularmirror @beatascienceart maryoreilly.substack.com/?utm_source=na… #sciart

A couple great resources for people interested in #Sciart. Mary O’Reilly’s newsletter: maryoreilly.substack.com/?utm_source=na… And the Lasker Foundation Art of Science archives: laskerfoundation.org/category/the-a…

This week at #SABCS23: The @AACR will recognize Drs. Kornelia Polyak and @AlanaWelm for their significant contributions to breast cancer research. Learn more in SABCS Meeting News: bit.ly/3Rttrvx @LabPolyak #BCSM

Looking forward to presenting new sculptures of proteins and cells at #cellbio2023 today at 3:10p in subgroup “Science and Art: Bridging Two Creative Universes”, in room 254A. The full session is from 1-3p and has presentations from amazing scientist and artist! #SciArt

I like to make any biology pieces and I do have a soft spot for RNA biology ☺️. Thank you @1guramritsingh for giving me the opportunity to make this translating #ribosome and its #mRNA!

‼️🚨Kick off your weekend with an intro to a new, journal-free system for publishing—developed by and for scientists—that we’re piloting with our friends in immunology. Feeling intrigued? fed-up? skeptical? rebellious? Come watch the pitch! 😎 zoom.us/meeting/regist…

Here’s the nearly finished sculpture of the Src protein kinase. All the metal work is done, but it sits on a temp plywood base. Thinking about using a medium colored wood. Maybe lacewood? (I’m not a woodworker, ideas welcome!) The sculpture is bronze and steel.