Todd M. Brusko
@Bruskolab
Professor - Director at the UFDI- Father, immunologist, proponent of evidence-based policy. All opinions are my own.
Pleased to contribute to this exciting work on how HLA shapes the T cell receptor repertoire - TCR2HLA: calibrated inference of HLA genotypes from TCR repertoires enables identification of immunologically relevant metaclonotypes biorxiv.org/content/10.110…
Super cool thread on how tech interfaces with biology to provide novel insights.
1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too…
Yes. Writing is not a second thing that happens after thinking. The act of writing is an act of thinking. Writing *is* thinking. Students, academics, and anyone else who outsources their writing to LLMs will find their screens full of words and their minds emptied of thought.
Urge the U.S. Senate to Support T1D Research Funding - Breakthrough T1D www2.breakthrought1d.org/site/Advocacy?…
Excited to present this today at #ENDO2025 with Drs. Dirk Homann and Al Powers who organized. Swing by and join the discussion.
Michels et al integrate and summarize information about the pathogenesis of T1D, highlight gaps in current knowledge, and propose future activities that may lead to additional approaches to treat the underlying autoimmunity and β-cell defects in #diabetes. doi.org/10.1210/clinem…
A new grant from the American Diabetes Association's Innovative Translational Clinical Science program was awarded to Dr. Ashby Walker, Director of Community and Population Health for the UFDI. This grant will allow the highly successful ECHO Diabetes program to grow into a…
Happening today! Come out to hear about spatial transcriptomics in T1D as Miguel defends his dissertation.
Epic day on the water yesterday. Hogfish, flounder, Black Sea bass and white grunts…topped off with fresh homemade smoked mullet dip. Hope everyone enjoyed the 4th!
TrialNet screens families of people with T1D & offers clinical studies testing ways to slow down & prevent disease progression. Our free at-home screening kits can be shipped anywhere in the US & Canada.
Type 1 diabetes (T1D) knows no boundaries—but access to screening and post-diagnostic care does. [1,2] Adolescents and young adults in rural communities are at greater risk of delayed diagnosis of T1D, often presenting with life-threatening diabetic ketoacidosis (DKA). [2]…
Take a look at our UFDI spotlights today at the @AmDiabetesAssn 85th Scientific Sessions! #ADASciSessions
Strong work by @UFEndocrinology at #ADASciSessions #ADA2025 1 consensus report review on MASLD 3 oral presentations 8 poster presentations! Key take aways: 1. Screen all high risk patients with FIB-4 More ⬇️
 Today’s speaker lineup at the @AmDiabetesAssn 85th Scientific Sessions features Alexandra E. Cuaycal, PhD, Srilaxmi Kalavalapalli, MS, MBA, and Anu Sharma, MD, presenting key research on type 1 diabetes, liver fibrosis, and type 2 diabetes outcomes. @AnuSharma1025 @UFHealth…
🚨NEW - In vivo CAR T cell generation to treat cancer and autoimmune disease @capstantx direct delivery of mRNA-encoded CARs to CD8+ T cells in mouse & NHP models shows tumor control not only in blood, but also tissue. Immune reset seen at B cell recovery science.org/doi/10.1126/sc…
T follicular helper cells can play unconventional immunoregulatory roles, such as supporting cytotoxic #Tcell responses and producing effector-like cytokines to shape #Bcell fates, according to a new Review. Read more in Science #Immunology: scim.ag/3SQqyoq
🎉 We're heading to Boston to celebrate 25 years of FOCIS! Don't miss out — registration for the FOCIS 2025 Annual Meeting closes Monday, June 16. Beat the price increase and register this weekend! 👉 Register now zurl.co/zBK3h #FOCIS2025 #Celebrating25Years
Excited to share a preprint reporting on the cellular and molecular immune profile of human T1D from @DiabetesnPOD. Aberrant immune regulation and enrichment of stem-like CD8+ T cells in the pancreatic lymph node during type 1 diabetes development biorxiv.org/content/10.110…
🚨New work from our lab with important clinical implications. Thanks to our collaborators in @TheHPAP. Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes | bioRxiv biorxiv.org/content/10.110…