Brad Spellberg

Thanks to @absteward for finding the most recent Shorter is Better: TB Is Complex Study. Shows 8 week regimens are inferior to 24 week for cure. Sets a lower boundary for TB. Slides and website updated. bradspellberg.com/shorter-is-bet…

Zero humility in the uncertainty of this, which is why @Wiki_Guidelines is important

Absolutely.... clinicalmicrobiologyandinfection.com/article/S1198-… But but but the microbiome!!!

And doesn’t ASP have more adverse effects than cefazolin? It’s also a pain (literally) to administer.

I would be ecstatic if my biggest stewardship concern was between cefazolin and ASPs 😅😅😅 but alas

We’re proud to announce that LA General Medical Center has earned Magnet® designation—the gold standard for nursing excellence. First in LA County’s DHS and among few safety-net hospitals nationwide to receive this honor. instagram.com/reel/DMbQK_KNS…

This highlights why we must urgently stop using these terms.

The concept of static/cidal antibiotics is neither complex nor context-dependent; it is rather a myth It’s my honor to contribute to this letter spearheaded by @BradSpellberg

Great thread of some brilliant folks (not me) discussing GPC bacteremia What I gathered (basically): -Empirically likely no benefit of BL+Vanc -Vanc most common empiric monotherapy -BL > Vanc for MSSA -Cefazolin > other BLs for MSSA -As always, tailor to patient when possible!

Say. It. Louder. 👏🏼👏🏼👏🏼 Credit: @BradSpellberg , @austincamp

THANK YOU!!! That’s what I’ve been trying to tell people!! Vanco empirically then cefazolin if MSSA but not dual therapy on everyone.

LOL. I usually switch people FROM vanco TO linezolid rather than the other way around.