Andrew Brack
@BrackLab
Scientist interested in preventing functional decline during aging. Program Manager at ARPA-H. Interests: Crypto, Everton FC and Boxing. Views are my own.
What if we had therapies to extend healthspan and prevent the onset of age related diseases? I’m excited to announce my first @ARPA_H program, PROSPR. The goal is to develop validated surrogate biomarkers, new clinical endpoints and therapies to collectively extend healthspan…
What if we could predict age-induced health issues before they happen? Our new PROSPR program aims to identify biochemical and physiological markers, paving the way for faster, more targeted aging research. arpa-h.gov/news-and-event…
I’m super excited about this one
ARPA-H launches groundbreaking funding opportunity to improve clinical trials arpa-h.gov/news-and-event…
F.D.A. Panel to Reassess Hormone Therapy Warnings @DrMakaryFDA the agency’s commissioner, has said too many women avoid menopause treatments because the risks have been overstated (& I agree👨⚕️) "...proponents like Dr. Makary say there’s evidence that hormone therapy — approved…
Join ARPA-H Program Manager Dr. @BonKu for a walkthrough of PARADIGM’s prototype technology! Our PARADIGM program asks, what if we could deliver advanced hospital-level care to every rural county in America? arpa-h.gov/explore-fundin…
Healing from within to restore brain health. From Alzheimer’s disease to traumatic brain injury, FRONT aims to revolutionize how we treat brain damage and restore cognitive function. 🧠 📅 Register by August 5 for FRONT hybrid Proposers' Day on August 8: arpa-h.gov/explore-fundin…
Step Aside Longevity Bros. It’s Time for the Longevity Ladies. 🔗wsj.com/health/wellnes… 🌟@jenngarrison @DenaDubal @LouiseAronson Kayla Barnes-Lentz @femalelongevity, and Ella Davar. 👉"A growing number of female scientists, entrepreneurs and influencers are edging into a…
LETS GO! A new high impact program from @ARPA_H. FRONT will restore lost function to the brain. Congrats to @Replacing_Aging and team.
NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…
How can we translate cutting-edge geroscience into medicines that will benefit humanity? This week's special episode features a live panel from the 25th Bay Area Aging Meeting, where six leading voices across academia, industry, and publishing tackled the critical challenge of…
I couldn’t agree more with @mkaeberlein here. These limitations are why we built PROSPR🖖🏻
What doesn’t work in longevity medicine today? Direct to consumer biological age and microbiome tests. Why do I say that? (1) The don’t measure what they claim to measure (2) They provide no information on precision or accuracy (3) There is no industry quality control (4) There…
The internet, mRNA vaccines, and self-driving cars all came from ARPA-style programs led by technical visionaries. Yet there’s no systematic pathway for technical visionaries to get the skills and support needed to develop such programs. Big news 👇
One of the great pleasures of working as a PM at @ARPA_H is that I get the chance to speak with all potential performers to clarify the decisions made to encourage or discourage proposals, and to take questions. It provides a layer of transparency and accountability to the…
Big news: we’re kicking off the search for ARIA’s next CEO. This is a once-in-a-lifetime opportunity to lead one of the most ambitious orgs in science and tech. 1/8
PROSPR will identify therapeutic solutions to prevent associated functional declines. The mechanisms that reverse functional declines in the elderly (rejuvenation) are likely different. Who is doing exciting work in the rejuvenation space and what are some exciting opportunities…
People should be free to choose what they do with their bodies—but freedom is only meaningful if the information is accurate, balanced, complete. Overselling benefit and downplaying risk with something as complex & irreversible as gene therapy isn't innovation — it's exploitation
During my talk I specifically called out these gene therapy clinics and they way they are operating. I suggested one improvement would be an independent body that collects and aggregates the data on both efficacy and adverse events. Afterward folks from the conference shared some…
During my talk I specifically called out these gene therapy clinics and they way they are operating. I suggested one improvement would be an independent body that collects and aggregates the data on both efficacy and adverse events. Afterward folks from the conference shared some…
Sitting here at day 2 of @LongevityDublin feeling uneasy with the presentation from TripleHelix about what they are doing with gene therapy outside of any regulation. Then the guy starts talking about SIRT1 gene therapy, and now I'm certain they don't know what they are doing.…
Join us in Crete to discuss Stem Cells. The early bird deadline has been extended to July 15th. This date will be the final deadline for abstracts being considered for short talks. aegeanconferences.org/src/App/speake…
Healthspan Effects of an Anti-Aging Vaccine on Mice The vaccine partly restored age-related NAD+ decline. @DrangowskaWay @LifespanNews lifespan.io/news/healthspa…
Important update on Alzheimer's -Need to start prevention much earlier than waiting for symptoms. nih.gov/news-events/ne… @nationallipid @society_eas @ASPCardio @escardio @atherosociety
📣 Evidence drives science, but stories drive change. We’ve got the data. The clinical trials. The potential to radically extend healthspan and prevent disease. Now we need you to speak up and get involved! If you believe in the promise of longevity science and want to help…
Now is the time for grassroots action. While headlines swirl with political turmoil and federal funding for biomedical research faces cuts, one truth remains: Americans are living longer, but not healthier. A declining healthspan doesn’t just strain families and our healthcare…
Who thinks Intrinsic Capacity should be tested in response to gero-therapeutics in large scale aging human studies?
HealthAge: evaluation of intrinsic capacity changes in humans, mice, and killifish to explore the biology of aging pubmed.ncbi.nlm.nih.gov/40518489/