Frédéric Blanc 🇨🇵 🇪🇺
@BlancFrdric7
Professeur Gériatrie Neurogériatre. MD, PhD, HdR. CM2R @CHRUStrasbourg, #ICube @Unistra #corpsdeLewy #Alzheimer #LewyBody, free articles http://univoak.eu
🧠 𝐃𝐞𝐥𝐢𝐫𝐢𝐮𝐦 𝐓𝐨𝐝𝐚𝐲, 𝐃𝐞𝐦𝐞𝐧𝐭𝐢𝐚 𝐓𝐨𝐦𝐨𝐫𝐫𝐨𝐰? ▶️ Multiple studies now show that delirium is a major risk factor for dementia. ⁉️ It's a puzzle why delirium is hardly mentioned in the dementia literature, including as a risk factor for dementia. 🧩…
AMPAR antibodies encephalitis, with MRI hypersignal of hippocampi, amygdalae, cerebellum and #catatonia.
Anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor encephalitis presenting as catatonia | BMC Psychiatry | Full Text bmcpsychiatry.biomedcentral.com/articles/10.11…
Implications and opportunities regarding biological frameworks (of Alzheimer's disease and Parkinson's disease) in overt and prodromal dementia with Lewy bodies. Excellent coordination by Jennifer Goldman for this review article. @LBDAssoc alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…
Lecanemab in a Specialty Memory Clinic: Patients with mild dementia had a 27% rate of symptomatic ARIA; those with mild cognitive impairment or very mild dementia had a 1.8% rate. jamanetwork.com/journals/jaman…
Excellent scale for delirium: 4AT 👍
“... the committee agreed that the 4AT was the best option for most settings. It is among the most accurate of the tools reviewed, quick and simple to use, and has a broader range of evidence to support it.” — UK NICE Guideline on #Delirium, 2023
The converging paths to hippocampal sclerosis of ageing: insights from LATE-NC and vascular disease New scientific commentary by Ryan Coburn and Hugo Botha tinyurl.com/3ffhrkm7
Human Pegivirus and Parkinson's disease? Perhaps. insight.jci.org/articles/view/… Interstingly, human Pegivirus can be responsible for encephalitis next to substantia nigra... nejm.org/doi/10.1056/NE…
@BlancFrdric7
La catatonie chez la personne âgée: penser à la bipolarité, la maladie à corps de Lewy et la maladie frontotemporale (notamment). jle.com/fr/revues/gpn/…
Comment traiter les symptômes psychocomportementaux de la maladie à corps de Lewy? Un article du groupe Lewy pour les recommandations natoanles en France (SFGG, FCM, SF3PA). jle.com/fr/revues/gpn/…
L’A2mcl ouvre un nouveau Google Groups dédié aux jeunes de 15 à 25 ans confrontés à la maladie à corps de Lewy d’un proche. Comprendre et en parler, à travers un espace de parole co-animé par Yael Slama, psychologue et Djilane Sene-Roux, jeune bénévole et ex aidante.
The average pooled prevalence of apathy: 57% in dementia with Lewy bodies (DLB), 56% in Parkinson's disease dementia (PDD), 46% in DLB-MCI, and 38% in PD-MCI. High reate of apathy in synucleopathies, when cognitive impairment. alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…
Prodormal dementia with Lewy bodies, a cause of late-onset unexplained epilepsy. High interest of alpha-synuclein seed amplification assays (SAA, RT-QuIC). Well done Augustin Moreau and Benjamin Cretin form team Strasbourg DLB 👍😉 sciencedirect.com/science/articl…
Parkinson : 3 signes non moteurs pour prédire la maladie La co-occurrence de la constipation, d’1 trouble du comportement en sommeil paradoxal & de l'hyposmie multiplie par 23 le risque de diagnostic de Parkinson dans les 3 années suivantes @BlancFrdric7 jim.fr/viewarticle/pa…
🧵 FIL : Des chercheurs viennent de découvrir comment les cellules cancéreuses piratent… nos neurones 🧠 en leur piquant leurs mitochondries ⚡ pour mieux se propager dans le corps. Un papier majeur pour comprendre comment les métastases prennent le dessus 👇 #Cancer 1/ ⤵️
Subjective cognitive impairment or mild cognitive impairment dementia with Lewy bodies: if amyloid positive, more global cognitive (Mini-Mental State Examination) and functionnal (CDR) decline. Very proud of this article with the Memento cohort. alz-journals.onlinelibrary.wiley.com/doi/10.1002/da…
📢New Open🔓 Access Paper in GeroScience Cognitive and neuroimaging outcome of very prodromal dementia with Lewy bodies by Frédéric Blanc (@BlancFrdric7) & Carole Dufouil et al. rdcu.be/eqT1C #dementia #LewyBodies #alzheimersdisease #prodromal…
La demencia con cuerpos de #Lewy y su impacto en la Fase prodrómica (temprana), crea mayor disfunción y menos degeneración
"Dementia with Lewy bodies would therefore be a less degenerative and more dysfunctional disease at the prodromal stage". Very proud of this article from the Memento cohort, which includes patients with SCI and MCI. rdcu.be/enEc4
Voici la vidéo de ma prise de parole, hier après-midi, lors de la mobilisation des éligibles et des aidants contre la folie de "l'aide à mourir" (#Euthanasie). Mesdames et messieurs les députés ayez le courage de dire "Non" en votant contre ce texte de loi ! Refusez cette lourde…
"Dementia with Lewy bodies would therefore be a less degenerative and more dysfunctional disease at the prodromal stage". Very proud of this article from the Memento cohort, which includes patients with SCI and MCI. rdcu.be/enEc4