Dr. Bianca Introini

❄️🌈 Now out in Nature Methods: nature.com/articles/s4159… Couldn’t be happier!

Difference between diffusion and flow? If you drip paint into a river it locally dissolves by diffusion. It goes downstream driven by flow. We quantify flow through #nuclearpores in response to rapid nuclear size changes. @MPIbp #TEAMTOMO @MolecularCell cell.com/molecular-cell…

Feeling festive? The Smart Biology team reveals our most viewed animations of 2024. Press like if our top 10 picks make your holiday brighter! To start it off at #10, the dinosaur hiding in the rough endoplasmic reticulum. #Biology #3D #Education #Animation🎄🎬

Why are some chromosomes like #21 in Down syndrome more error-prone in mammalian eggs? 🤔 Our new study in @NatureComms reveals why acrocentric chromosomes often mis-segregate, causing aneuploidy and miscarriages. (1/9) nature.com/articles/s4146…

The study of KIF4A-mediated human condensin I activation is out! Congrats to @cutts_dr, L. Aragon, @DamlaTetiker !

🎄It’s Beginning to Look a Lot Like Christmas... Under the Microscope!🔬 Why buy Christmas trees when you can "grow" one using micropatterning ( @AlveoleLab ) and @AllenInstitute 's cells with LaminB1 "ornaments"? Happy #FluorescenceFriday !

… and perfect timing. Work by @HuaipengXing with @FrydmanLab out @Nature. PDCD5 binds virtually all open #TRiC, while closed TRiC forms clusters inside of cells. Congrats to all authors. rdcu.be/d3dmN

Find our fresh peer-reviewed report on “Molecular Architecture of Synaptic Vesicles” here: pnas.org/doi/10.1073/pn… We analyzed synaptic vesicles in neurons and in isolation to describe molecules on their surface. 🧠💥🔬

DNA during cell death and cell division. #CellBiology #microscopy

Chinese scientists at Shanghai Jiao Tong, working with MIT, engineered a new desalination device. It turns seawater into drinkable water at a rate higher than any other device. The system is passive, & solar-powered. A system the size of a small suitcase meets the daily needs of…

Thrilled to share our new work @biorxivpreprint: biorxiv.org/content/10.110… Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live cells. We reveal genome chromatin is essentially replicated from regions with greater nucleosome motions. 1/2

Each month an #egg is ovulated from the #ovary, starting the journey of reproduction. But how does ovulation occur?🥚 Our latest work in @NatureCellBio led by @LastChrisThomas and @Tabea_Marx, describes the control of #ovulation using live imaging. bit.ly/3Ya8dEL (1/7)

Did you know that nuclear pore complexes can turn up outside the nuclear envelope? Studying these, @JennySachweh, Bernhard Hampoelz and others uncover that the surrounding cellular milieu determines NPC composition via the nuclear transport system itself. #teamtomo #NPC A 🧵

Transplacental SARS-CoV-2 protein ORF8 binds to complement C1q to trigger fetal inflammation Uninfected fetal tissues exposed to the SARS-CoV-2 cytokine ORF8 through an infected mother have higher rates of inflammation embopress.org/doi/full/10.10…

My babies are on the cover of The EMBO Journal! I couldn't be happier and prouder of this journey alongside with my colleagues and collaborators, which has led to this amazing publication. Enjoy it once again!😌 @MishaKudryashev @MPIbp

Issue 20 kick-starts our metabolism review series with @JohannesMeiser & @FrezzaLab Structure of the type I-F Cas8-HNH system Fitness cost of spurious phosphorylation Resource: i-motif distribution in the human genome Cover: @MishaKudryashev and colleagues embopress.org/toc/14602075/4…

First experiment with #MDanalysis in #MolecularNodes Does anyone have any advice for cleaning simulations for particles moving too quickly? Some phospholipids are a bit glitchy. NhaA equilibrium dataset from Ian Kenney and Shoji Fan figshare.com/articles/datas… #Blender3D #sciart