Benjamin Kroeger

🍾Our paper is officially out today in @Dev_Cell. Delighted to share it with y'all: authors.elsevier.com/c/1iIEp5Sx5gtx… Thanks again to the rest of the team involved, especially @schmanning, Yoshana Fonseka, @GeorgRamm & @HarveyHippoLab Tweetorial🧵👇

First paper of our lab today @Nature by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using multi-color #single-molecule FM: we find long-range #ribosome-#polymerase communication mediated by #RNA looping! @embl doi.org/10.1038/s41586…

It took a lot of effort to figure out, but here it is: the Drosophila haltere displays wing-like dorsoventral adhesion (surprise!) and that is essential for shaping its 3D architecture in a very interesting way biorxiv.org/content/10.110…

Our new paper is out @ScienceAdvances👇 science.org/doi/10.1126/sc… 🧬Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live human cells. 🔍@katsu_s_minami et al.have developed a chromatin behavior atlas within the nucleus. 1/2

Lab’s latest: (mouse) mums grow their guts during pregnancy and lactation: cell.com/cell/fulltext/…

🧬A new imaging technique developed by the Liu Lab uses a novel DNA barcode system to track hundreds of RNA & protein molecules in single cells within thick biological samples, providing a full picture of how these structures are organized inside tissues. janelia.org/news/new-metho…

Stoked to present our latest, brilliantly led by Chris et al & Alejandro Torres-Sanchez. How tissues are patterned during development – we found that geometry-constrained ECM fractures pattern the myocardium in the vertebrate heart 1/n biorxiv.org/content/10.110…

Our new preprint is out＠bioRxiv: biorxiv.org/content/10.110… @MasaAShimazoe et al. reveal that linker histone H1 acts as a liquid-like "glue" to organize chromatin in living cells. 🎉 Fantastic collab with @rcollepardo, Charlie Phillips, @janhuemar and others—huge thanks! 🙌 1/2

Cellpose3: one-click image restoration for improved cellular segmentation Carsen Stringer & Marius Pachitariu nature.com/articles/s4159…

After a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. nature.com/articles/s4159…

I am thrilled that our work on MemGraft probes for “permanent” fluorescent labelling of plasma membranes is out in @JACS_Au! We established a concept of lipid-directed covalent labeling of plasma membranes. Open access: pubs.acs.org/doi/10.1021/ja… MemGraft probes allow cell fixation,…

Could one envision a synthetic receptor technology that is fully programmable, able to detect diverse extracellular antigens – both soluble and cell-attached – and convert that recognition into a wide range of intracellular responses, from transgene expression and real-time…

Have you ever wanted to *see* receptor activity in embryos? If so, our new preprint is for you! In it, we showcase a new live-cell biosensor for visualizing receptor tyrosine kinase activity in living embryos – pYtags! biorxiv.org/content/10.110…

A simple MiMIC-based approach for tagging endogenous genes to visualise live transcription in Drosophila Read this Techniques and Resources Article by Lauren Forbes Beadle, Catherine Sutcliffe and Hilary Ashe @TheAsheLab @OfficialUoM: doi.org/10.1242/dev.20…

This week we were happy to announce the winner of the Royal Society Publishing 2024. 'The hunt from above' by Dr Angela Albi is a stunning bird's-eye view of four sharks hunting a group of schooling fish in the crystal-clear waters of the Maldives. Find out more:…

Even our embryos are starting to feel a little festive in the Srinivas lab! We are happy to share our new bioRχiv pre-print – investigating the role of calcium in the early embryo biorxiv.org/content/10.110…

Happy fluorescence Friday from this Xenopus tadpole head highlighting migrating microglia (green) and neurons (magenta) 🐸🔬🧠 By: Micaela Lasser, Helen Willsey @goodfrognosis lab @zeiss_micro Axiozoom + apotome

APEX peroxidase is a versatile tool for proximity labeling and electron microscopy (EM) but its requirement for toxic H2O2 is a liability. We now report LaccID, a multicopper oxidase evolved from an ancestral fungal laccase that oxidizes aromatic substrates using non-toxic O2…

Thrilled to share our latest work from my postdoc with @MartinLabMIT in @Dev_Cell ! We uncovered a mechanism linking DV axial patterning with AP axis extension through patterned cell-cell adhesion. Intrigued? Dive into the details here!

#ExM has transformed how we perceive the microbial diversity all around us. Some gorgeous critters from the @EMBLHeidelberg pond - DNA red, centrin yellow, tubulin gray, images courtesy @F_Mikus. Bonus points if you can identify at least 4! Want more? biorxiv.org/content/10.110…

Excited to share our latest research in @NatureComms! Discover how SUMOylation of Warts kinase promotes neural stem cell reactivation. @GaoYang43766353 @jiaen_lin @mahekta @LukeKunYangLin1 Read the full paper here: nature.com/articles/s4146…