Alessandro Bartolomucci Lab

Out today @NatureAging ! Life stress can accelerate aging and shorten lifespan, but how remains unclear. We identify that hippocampal/cortical neurons acquire features of p16-dependent #senescence and DNA damage in mice exposed to chronic social stress. nature.com/articles/s4358…

Remider! Applications for the McEwen Career Development fellowship in Social Determinants of Health supported by the NIA-BSR High Priority Research Network animalsocialaging-network.org are now open! apply here animalsocialaging-network.org/funding/fellow… @BartolomucciLab @SMack_Lab @jtung5

Interested in organizing a workshop to collaborate, dialogue, and produce research relevant to Animal Models for the Social Dimensions of Health and Aging? Applications for Small/Working Group Meeting grants are now open! animalsocialaging-network.org/funding/small-… Deadline: 07.31

Reminder!!!! 📢Applications are OPEN for our Pilot awards! Individual or mentored projects available with up to $20,000 in total costs! Read the full RFA and apply at the link below! animalsocialaging-network.org/funding/pilot-… @animalsocaging

Signals of energetic stress including GDF15 and others reach the brain to influence the aging process Superb journalistic writing by @DianaMKwon With contributions by @Dr_Epel @BartolomucciLab @sturm_gav and Anthony Zannas nature.com/articles/d4158…

Reminder - funding opportunity available trough the @animalsocaging Pilot & Feasibility Awards Applications: June 1 to June 30 B. McEwen Career Development Fellowship Applications: June 15 to July 15 Small/Working Group Awards Applications: July 1 to July 31

New Study from the lab out at @GeroScienceAGE ! Mathematical models identified epigenetic biomarkers of mortality risk and an association with blood glucose levels, informing on individual aging trajectories. link.springer.com/article/10.100…

Interested in learning more about our NIA-funded network? Check out this @ScienceMagazine feature video from 2020 shortly before our network launched, then visit our website to learn more about available funding opportunities! animalsocialaging-network.org youtube.com/watch?v=lwICwI…

Indeed, very cool result that matches the co-evolutionary history of TLQP-21 and C3aR pubmed.ncbi.nlm.nih.gov/31484069/

Congratulations @arshukla for yes another fantastic study on C3aR (and C5aR) and its endogenous and synthetic ligands!!!

📣New network funding available soon!📣 The Request for Applications for our Research Network's pilot awards, small/working group awards, and the Bruce McEwen Fellowship will go live beginning on June 1, 2025. See the post below for details! @SMack_Lab @BartolomucciLab @jtung5

A couple of leadership updates! Congratulations and welcome @SMack_Lab (ASU) to our network PI team. We look forward to growing this vibrant community with you! @BartolomucciLab has also been named contact PI on the NIA R24 renewal. Subaward application details announced soon!

We're thrilled to announce that the NIA R24 grant that supports the Animal Models for the Social Dimensions of Health and Aging Research Network has been renewed through 2030! Thank you to everyone who made this renewal possible. New funding applications to be announced soon!

Congratulations Jenny!!!!!

We recently published @GeroScienceAGE the development and validation of the mouse social frailty index (mSFI) link.springer.com/article/10.100… We now report a detailed step-by-step @bioprotocolbyte resource paper describing how to conduct the mSFI. bio-protocol.org/en/bpdetail?id…

Bringing to your attention this National Academies Workshop on the neurobiology of stress and resilience across the lifespan. I’m honored to be co-chairing it with ⁦@EricJNestler⁩. A wonderful lineup of speakers & participants with lived experience. nationalacademies.org/event/43074_03…

Interesting paper in this week's issue of @ScienceMagazine (science.org/doi/10.1126/sc…) on a neural circuit mediating preference for sweet food after a meal. (1/3)

At aging-us.com we're seeking original research, reviews & perspectives on aging & age-related diseases, including: - Biology of aging - Translational & clinical research - Epidemiology & multi-morbidity Submit your best work! #AgingResearch #Longevity #AgingUS

Chronic social stress induces p16-mediated senescent cell accumulation in mice nature.com/articles/s4358… | @BartolomucciLab

Thanks to all the fantastic members and awardees of the @NIA_BSR-funded @animalsocaging Network, for a fantastic meeting - and to @UNCPopCenterfor hosting! @SMack_Lab @jtung5 @BartolomucciLab @BrianMSweis @rhernandezpach @CamilleTestard @MatthewZipple @GaganWig @IDsignals

January issue of @NatureAging out. Proud to have our paper on #stress causing DNA damage and #senescence in neurons and other organs - alongside many other excellent papers on #senescence (immune clearance, senolytics, p21high SNC etc). nature.com/articles/s4358…