Alexandre Dumoulin @axonsalex.bsky.social

Finally out! 🥳We added a lot of rescue experiments. We now show that Arl13b needs to locate to commissural neurons primary cilium for proper rostral turning of axons. We also further characterized Shh retrograde transport to the soma of comm. neurons. journals.biologists.com/dev/article/do…

This time-lapse captures 17h of axonal growth from a chick dorsal root ganglion explant, seen through the actin cytoskeleton using live imaging. I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours!😉 #neuroscience

Come and join the Williams lab @OfficialUoM @FBMH_UoM @The_MRC We are using single-cell Multiomics and in vivo CRISPR approaches to understand the molecular mechanisms underlying lineage segregation from the neural plate border 🐣jobs.manchester.ac.uk/Job/JobDetail?…

I’m very excited to finally present something we’ve been working on for the past couple of years – a spatial proteome map of primary cilia, released in @ProteinAtlas today. Amazing teamwork led by @jn_hansen Check out our preprint doi.org/10.1101/2024.1…

The punishment for science misconduct is …. nothing. All these men are still running labs / paid professors.

Baby you’re a fiiiiirework!!! Explanted Xenopus neural crest cell, microtubules (green) and actin (magenta). Imaging in frogs rocks- this is done room temp, no incubation, no problem. 🐸🔬✨ By Micaela Lasser, Helen Willsey @goodfrognosis Lab @zeiss_micro LSM980 fast airyscan

Time-lapse recording of floorplate cytonemes (green) interacting with axons (magenta). 1 image taken every second for 10 min (played at 30 fps). Cytonemes love interacting with axons! 💚#FluorescenceFriday

Retinoic acid, an essential component of the roof plate organizer, promotes the spatiotemporal segregation of dorsal neural fates Read this #OpenAccess Research Article by @DinaRekler, Shai Ofek, Sarah Kagan, Gilgi Friedlander & @ChayaKalcheim @HebrewU: journals.biologists.com/dev/article/15…

Everyone will run into something like this in their career if they keep their eyes open. What will you do? thetransmitter.org/science-and-so…

Monday morning, after the third ☕️, an excellent time to complete the @Actionuni1 survey

The Vollum Institute is accepting applications for multiple faculty openings. We are interested in individuals whose research focuses on molecular and cellular neuroscience, genetics, neurodevelopment or signal transduction. #sciencejobs #neurotwitter academicjobsonline.org/ajo/jobs/28203

Hold on to your hats! The winners of the 2024 #NikonSmallWorldInMotion competition have finally been revealed, and they're sure to blow you away. View the full video gallery here: bit.ly/47t3L8A

Lineage tracing of signaling pathway-responding cells to find out new developmental relationships during myogenesis 😎 Hope you’ll enjoy it ! biorxiv.org/content/10.110…

AXON2025 is gearing up! If you're passionate about neural circuit development, this is the must-attend event of next year — set in an extraordinary, non-conventional location🚢that you won’t want to miss! #AXON2025 @JeroenPasterk

Those neurons were cultured in a microfluidic chamber slide to separate axons (right-hand side) from the somata (left-hand side). #FluorescenceFriday

Chicken commissural neurons stained for neurofilament-M (Cyan) and the primary cilium marker Arl13b (red). happy #FluoresenceFriday !

To find out more about this work, we caught up with first author, Alexandre Dumoulin, and corresponding author, Esther Stoeckli, Professor @UZH_en: journals.biologists.com/dev/article/15…