Maciek Antoniewicz
@AntoniewiczLab
Professor @UMich. Microbiome, biotechnology, and cancer research. Quantifying metabolism, engineering metabolic pathways, adaptive evolution, systems biology.
My article on gene synthesis is in @nytimes today. Thanks to everyone I spoke to at @TwistBioscience and @Ginkgo for your help and to @winstonxyan for originally tipping me off to the topic. google.com/amp/s/www.nyti…
Happy New Year from the top of Africa! It's never too late to start living your dreams. I reached the summit of Mount Kilimanjaro at 6.55am on 1/1/2024. #Kilimanjaro #Tanzania

Five MIT faculty elected to the National Academy of Sciences for 2023: Joshua Angrist, Gang Chen, Catherine Drennan, Dina Katabi, and Gregory Stephanopoulos are recognized by their peers for their outstanding contributions to research. mitsha.re/eKXX50OmtCR
Congratulations to Harry Cai and Lauren Cordova for winning awards for outstanding posters at the Cell Culture Engineering XVIII Conference in Cancun, Mexico!

Great to meet up with past Antonieiwcz Lab members Ellie Oates (PhD, 2020), Woo Suk Ahn (PhD, 2012), Harry Cai (current) and Lauren Cordova (BS, 2015 @Lauren_CQ) at the Cell Culture Engineering XIII Conference in Cancun, Mexico (April 23-28, 2023).

13C Metabolic flux analysis of 3T3-L1 adipocytes illuminates its core metabolism under hypoxia doi.org/10.1016/j.ymbe…. Hypoxia reduces biosynthesis of mono-unsaturated fatty acids and odd-chain fatty acids from catabolism of branched chain amino acids. #flux #BCAA #metabolism

I think I have officially made it as a scientist... an external group published a genome scale model for an organism (Geobacillus sp. LC300) that I discovered and initially characterized ! 👩🔬🧪 sciencedirect.com/science/articl… @AntoniewiczLab @UDChBE
We are pleased to announce that our undergraduate Chemical Engineering (@UDChBE) program has placed second in the @usnews 2022-2023 Best Colleges rankings! udel.edu/udaily/2022/se…
Congratulations 🎉 to our new @UDChBE department chair, @MillieMSullivan! Sullivan is an expert in drug and gene delivery, biomaterials and regenerative medicine. We'd also like to thank @EMFurst who has served as chair since 2017. ow.ly/gy8j50JM6qZ #UDel #Hengineer
Congrats to @MillieMSullivan who will serve as Department Chair for @UDChBE starting July 1. She is a great scholar, educator, and leader. I am thankful for all she has already done in service to the department, and I am excited to contribute towards achieving her shared vision.
Today I decided that #directedevolution is finally ready to be run entirely by #machinelearning. No more painful experiments to get your long-dreamed-for #enzymes! Grad students and postdocs can just push a button.
13C Metabolic flux analysis of #Clostridium ljungdahlii illuminates its core metabolism under #mixotrophic growth. No catabolite repression by fructose on the use of CO2/H2. #Autotrophic #metabolism via Wood-Ljungdahl pathway remains dominant. Read more doi.org/10.1016/j.ymbe…

Our new work describing a “non-canonical” TCA cycle that is engaged in a cell-state dependent manner is out today in @Nature nature.com/articles/s4158…. Congratulations to lead authors @paigearnold2 @__btjackson @GSKGradSchool @MSKCancerCenter. A few highlights:
Coordinated reprogramming of metabolism and cell function in adipocytes from proliferation to differentiation. doi.org/10.1016/j.ymbe… Morphological and biomass composition changes in adipocytes are accompanied by significant shifts in metabolic fluxes. #flux #metabolism #13Cflux

"Be a free thinker and don't accept everything you hear as truth. Be critical and evaluate what you believe in." -- Aristotle (384 - 322 BC)
Instead of sending waste to landfills, @umich engineers are leading a renewable methane system inspired by cow stomachs, which looks to generate 40% more power from municipal waste streams at a 20% reduced cost. news.engin.umich.edu/2021/10/energy…
You are under no obligation to remain the same person you were a year ago, a month ago, or even a day ago. You are here to create yourself, continuously.
Remembering H. Scott Fogler (1939-2021). He changed the chemical engineering profession as a researcher, scholar, author, and, most importantly, a skilled and accomplished educator. che.engin.umich.edu/2021/08/24/rem…
Study hard what interests you the most in the most undisciplined, irreverent and original manner possible.
ChE @ Michigan mourns the unexpected loss of the venerable Professor Scott Fogler. He was a giant, and will be greatly missed.