AltisBiosystems
@AltisBioInc
Go with your gut—transform drug discovery with advanced human gut models for faster, precise insights into inflammation, toxicity, and ADME studies.
Why We Had to Build a Gut–Immune Co-Culture Model (And What It Means for IBD Research) Most gut models leave out the immune system. But if you're studying inflammatory diseases like #IBD… that's half the story gone. So we built something new—and human.👇
1/ 📝 “Developing IBD Counsellors in Low- and Middle-Income Countries: Bridging Gaps in Patient Care” In many low- and middle-income countries, patients with IBD face delayed diagnoses, fragmented care, limited specialist access, and overwhelming stigma.
It's promising to see scientists from @National_Ag_Lib, @DeptofDefense, & @NIH team up explore breaking down barriers to animal-free research. This paper includes suggestions for what academics, funders, & even IACUC members need to move the needle. altex.org/index.php/alte…
Diverticulitis, an inflammatory condition of diverticula, affects roughly 180 per 100 000 people annually in the US. This Review summarizes current evidence and treatment of diverticulitis. ja.ma/4m8t9qf @beccabrownmd
🔬 Endpoints in IBD: From Symptoms to Systems Biology Treat-to-Target in IBD is evolving—and so are the endpoints that define success. Here’s what we aim for: ✅ Clinical Remission 🧾 PROs (Patient-Reported Outcomes) 🔬 Mucosal, Histologic & Transmural Healing 📉 Biomarker…
🚨In case you missed it: Altis' new SLAS Discovery study highlights a gut-immune co-culture model using RepliGut® + THP-1 macrophages. Reproducible inflammation. Real therapeutic insights. 🔗 hubs.ly/Q03xls5W0 #IBD #RepliGut #DrugDiscovery #MPS #SLASDiscovery #invitro
🚨 New Publication Alert! We developed a human gut–immune co-culture model that mimics inflamed intestinal conditions for IBD research. ✅ RepliGut® colon + THP-1 macrophages ✅ Distinguishes anti-TNF vs JAK inhibitors ✅ Reproducible, HTS-compatible hubs.ly/Q03xls5W0
Mayo Clinic Talks—Check out our #IBD podcasts—here’s the first one on diagnosis @DavidBruiningMD open.spotify.com/episode/2ThgCW…
😴 Kids with IBD often suffer from fatigue—but there’s hope! ✅ Sleep tracking and sleep hygiene counseling improved fatigue scores in this RCT of youth with IBD. 🛏️ Simple steps = better sleep & less fatigue. 🔗 doi.org/10.1002/jpn3.7… #pediatrics #IBD #pedsgi
🚨 New Publication Alert! We developed a human gut–immune co-culture model that mimics inflamed intestinal conditions for IBD research. ✅ RepliGut® colon + THP-1 macrophages ✅ Distinguishes anti-TNF vs JAK inhibitors ✅ Reproducible, HTS-compatible hubs.ly/Q03xls5W0
Don't miss @NKleinstreuer's recent conversation with @NIHDirector_Jay!
.@NIHDirector_Jay and Dr. @NKleinstreuer talk about NIH’s shift toward human-focused research and how NIH will no longer issue NOFOs exclusively for animal models. Watch the latest episode of The Director’s Desk to hear more: youtube.com/watch?v=iSvk6i…