Andrew Koutnik, Ph.D.
@AKoutnik
🔬Scientist of Metabolic Health & Human Performance 🏆Elite Performance Consultant & Diabetes Management Coach 🎙️Co-Host of In-Range with Max Domi
🧵Very-low carb (ketogenic; LCHF) vs high-carb diet (HCLF): -Ironman triathletes (n=10)🚴♂️ -"Hitting the Wall"🥵 -Homeostasis monitoring ("Keto-Adaptation")📈 Our hypothesis was wrong...again 🔍CRITICAL QUESTIONS: 1) Does adopting an LCHF diet impair strenuous time-to-exhaustion…

"Diet appears to be responsible for >90% of the obesity crisis in developed (and developing) countries!"
What are the relative impact of diet vs physical activity on the global obesity crisis? New paper out @pnas uses the DLW Database with 4000+ participants across 34 populations to investigate Obesity & Energy Expenditure Across the Economic Spectrum. Open access link below!🧵1/
Why hasn’t blood sugar control improved in Type 1 diabetes - despite cutting-edge technology advances? In this powerful episode, Dr. @AKoutnik breaks down: 🔹 The largest analysis of carb intake in T1D 🔹 Limitations of CGMs & pumps 🔹 A rare 10-year low-carb case study 🎧…
Why dont we protect farmers by subsidizing the transition to natural calorie free sugar alternatives? -Stevia -Monkfruit -Allulose
What an incredible visit with US Sugar! Florida’s sugarcane farmers are producing something truly special. Proud to support their work and the sweet success of American ag. 🇺🇸
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In universities, you don’t get canceled for being wrong. You get canceled for being right at the wrong time.
What happens when you propose dietary guidelines without evidence? You may spend 50 years giving sub-optimal advice... Example: 1st American Diabetes Association Guidelines 1971: "There no longer appears to be any need to restrict...the intake of carbohydrates in the diet of…

Interesting, watching today's stage in the Tour de France with the final hour being the climb to the top of Mount Ventoux, a very demanding hour of exercise. Yet it seemed that, certainly the lead riders (including Ben Healy) were rather restrained in what they were…
Sooner or later we are going to have to ask: What are the consequences of such high rates of carbohydrate ingestion in (almost totally) suppressing fat oxidation during exercise? In this study rates of fat oxidation after 3 hours of exercise were only 0.19 to 0.22 g/min. This is…
Sooner or later we are going to have to ask: What are the consequences of such high rates of carbohydrate ingestion in (almost totally) suppressing fat oxidation during exercise? In this study rates of fat oxidation after 3 hours of exercise were only 0.19 to 0.22 g/min. This is…
No Dose-Response to CHO with Exercise. Is this consistent? Major review forthcoming on this topic. Stay tuned. @ProfTimNoakes @PhilipPrins11
No Dose-Response to CHO with Exercise. Is this consistent? Major review forthcoming on this topic. Stay tuned. @ProfTimNoakes @PhilipPrins11
Should you consume carbs more or less frequently during exercise? Probably doesn't matter. In a new study, researchers had male cyclists ride for 3 hours at lactate threshold while ingesting 90 grams oe carbs per hour in one of two patterns: 1. 22.5 grams every 15 minutes or…
🐁 New Mouse (WITHOUT NNT) Study Suggest Ketogenic Diet Induced Oxidative Stress in Male but NOT Female 💥 🤔Interesting this doesn't seem to be the case in humans? 🔬Insight: 10 years ago I found that mouse models lacking NNT (key enzyme balancing mitochondrial ROS and…




A gesture like this during such a bad moment tells a lot about Remco. A good soul. That kid will always remember that bottle. 👍 #TDF2025
This is what the internet needs to see. 👇 @jockowillink
If I’m getting busted at a concert with my girl…it’s gonna be @BlackSabbath and the girls gonna be my wife!!!
Obesity Paradigm Shift. 👉Diet explains >90% of obesity epidemic 👉Remaining 10% -> Falling metabolic rate (not exercise)
and the other 10% explained by falling BMR NOT activity
Excited to share a milestone published in @NatureMedicine from our decade-long effort to build The Human Phenotype Project, a unique longitudinal cohort with unmatched depth of clinical and multi-omic profiling, enabling truly predictive, personalized medicine. Led together with…
If you don't regularly exercise, you are not at your full cognitive potential.